Zobrazeno 1 - 10
of 61
pro vyhledávání: '"S M, Rida"'
Autor:
S. M. Rida, Fawzia A. Ashour, Mostafa M.M. El-Miligy, Ehab M El-Bassiony, Mona H. Badr, Ashraf M Omar, Maha A El-Demellawy
Publikováno v:
Future Science OA
Aim: Simultaneous inhibition of hepatitis C virus (HCV) and hepatocellular carcinoma (HCC) may enhance anti-HCV effects and reduce resistance and side effects. Results/methodology: Novel hybrid derivatives were designed and synthesized to exhibit dua
Publikováno v:
Arzneimittelforschung. 62:63-74
Novel benzimidazoles, benzothiazoles and benzofurans incorporating pyrazole moiety have been synthesized and screened for their antiangogenic activities, by testing their ability to inhibit human umbilical vein endothelial cell (HUVEC) proliferation,
Publikováno v:
Medicinal Chemistry Research. 21:1107-1119
In an effort to etablish new candidates with improved antineoplastic, anti-HIV-1 and antimicrobial activities, the synthesis of some new triazino and triazolo[4,3-e]purine derivatives is described: 6,8-dimethyl-1,4-dihydro-1,2,4-triazino[4,3-e]purine
Publikováno v:
Letters in Organic Chemistry. 6:282-288
Publikováno v:
Archiv der Pharmazie. 340:185-194
In search of novel purine antimetabolites, a series of 8-substituted methylxanthine derivatives was prepared in order to explore their in vitro anticancer, anti-HIV-1 and antimicrobial activities. The target compounds include: 8-[(3-substituted-4-oxo
Publikováno v:
Archives of Pharmacal Research. 29:16-25
A novel series of 1-(1-benzofuran-2-yl-ethylidene)-4-substituted thiosemicarbazides (2a-d) along with some derived ring systems: substituted-2,3-dihydro-thiazoles (3a-c, 4a-f) and thiazolidin-4-ones (5a-d and 6a-d), were synthesized. In addition, cya
Autor:
Soad A.M. El-Hawash, Mona M. El-Semary, Manal Shalaby, Fawzia A. Ashour, Mona H. Badr, S. M. Rida
Publikováno v:
European Journal of Medicinal Chemistry. 40:949-959
In an effort to establish new candidates with improved antineoplastic, anti-HIV-1 and antimicrobial activities we report here the synthesis and in vitro biological evaluation of various series of 2-substituted benzoxazoles: 2-[(Arylhydrazono, arylide
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 127:1203-1207
A convenient and simple synthesis of 5-mercapto-3-phenyl-2-thioxo-2,3-dihydrothiazolo-[4,5-d]pyrimidin-7(6H-one(2) and its 5,7-dichloro (3), 5,7-diazido (4), 5,7-diamino (5), 5,7-dimerapto (6), 5,7-dimethylthio (7), and 6-methyl-5-methylthio (8) deri
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 127:1209-1214
Publikováno v:
Archiv der Pharmazie. 328:325-328
2-[(4-Oxo-4,5-dihydrothiazol-2-yl)methyl]-1H-benzimidazole (2) was prepared through the reaction of 2-cyanomethyl-1H-benzimidazole (1) with thioglycolic acid. The syntheses of its arylidene 3 and diazo-coupled compounds 5 and the cyclization of the a