Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S M, Poucher"'
Publikováno v:
The Journal of Physiology. 510:643-650
1. Male cats were anaesthetized with alphaxalone-alphadolone and breathed spontaneously following tracheotomy, Using coloured microspheres, muscle blood flow was measured at rest and during two periods of contraction elicited by simultaneous stimulat
Autor:
M C, Stephenson, E, Leverton, E Y H, Khoo, S M, Poucher, L, Johansson, J A, Lockton, J W, Eriksson, P, Mansell, P G, Morris, I A, MacDonald
Publikováno v:
NMR in biomedicine. 26(11)
The measurement of tissue lipid and glycogen contents and the establishment of normal levels of variability are important when assessing changes caused by pathology or treatment. We measured hepatic and skeletal muscle lipid and glycogen levels using
Publikováno v:
The Journal of Physiology. 427:19-29
1. A number of metabolites have been proposed to control the vascular tone of skeletal muscle during exercise. The present study was designed to investigate the role of adenosine in this response by determining the effect of the adenosine receptor an
Autor:
S M, Poucher, S, Freeman, S J G, Loxham, G, Convey, J B, Bartlett, J, De Schoolmeester, J, Teague, M, Walker, A V, Turnbull, A D, Charles, F, Carey, S, Berg
Publikováno v:
British journal of pharmacology. 152(8)
Studies in cultured hepatocytes demonstrate glycogen synthase (GS) activation with glycogen phosphorylase (GP) inhibitors. The current study investigated whether these phenomena occurred in vivo using a novel GP inhibitor.An allosteric GP inhibitor,
Autor:
P L, Greenhaff, S P, Campbell-O'Sullivan, D, Constantin-Teodosiu, S M, Poucher, P A, Roberts, J A, Timmons
Publikováno v:
British journal of clinical pharmacology. 57(3)
Peripheral vascular disease (PVD) is generally accepted to result in the failure of skeletal muscle blood flow to increase adequately at the onset of muscular work. There are currently no routine pharmacological interventions towards the treatment of
Autor:
Paul L, Greenhaff, S P, Campbell-O'Sullivan, D, Constantin-Teodosiu, S M, Poucher, P A, Roberts, J A, Timmons
Publikováno v:
Biochemical Society transactions. 30(2)
The oxygen deficit at the onset of submaximal exercise represents a period when the energy demand of contraction cannot be met solely by mitochondrial ATP generation, and as a consequence there is an acceleration of ATP re-synthesis from oxygen-indep
Autor:
S. M. Poucher, F. Karim
Publikováno v:
The American journal of physiology. 273(4)
The role of β- and α-adrenoceptors in the total vascular capacitance responses to changing pressure in vascularly isolated carotid sinuses of anesthetized and atropinized dogs was investigated. A change in vascular capacitance was determined by mea
Autor:
F Karim, S M Poucher
Publikováno v:
The Journal of physiology. 434
1. The effect of direct electrical stimulation of the renal efferent nerves upon renal haemodynamics and function was studied in greyhounds anaesthetized with chloralose and artificially ventilated. The left kidney was neurally and vascularly isolate
Publikováno v:
The Journal of Physiology. 417:295-305
1. In dogs anaesthetized with chloralose and artificially ventilated, the carotid sinuses were vascularly isolated and perfused with arterial blood. Mean aortic pressure was held constant at 111 +/- 2 mmHg (mean +/- S.E.M., n = 18) by means of a pres
Publikováno v:
The Journal of Physiology. 392:451-462
1. Dogs were anaesthetized with chloralose and artificially ventilated. The carotid chemoreceptors were stimulated by changing the perfusion of vascularly isolated carotid sinus regions from arterial to venous blood. The mean carotid sinus pressure a