IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding

Autor: R B Adams, S M Planchon, J K Roche

Publikováno v: The Journal of Immunology. 150:2356-2363

The single cell-thick intestinal epithelium forms a crucial barrier between the host and environment, and is modeled in vitro by a monolayer of polarized, highly differentiated T84 epithelial cells impermeable to most macromolecules because of functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27ca27f93e039315dd6360c004bcb9df
https://doi.org/10.4049/jimmunol.150.6.2356

Regulation of intestinal epithelial barrier function by TGF-beta 1. Evidence for its role in abrogating the effect of a T cell cytokine

Autor: S M, Planchon, C A, Martins, R L, Guerrant, J K, Roche

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 153(12)

Maintenance of the integrity of the single-cell-thick intestinal epithelium as an in vivo barrier between environmental Ags and mucosal immunocytes is pivotal for health. The T cell cytokine IFN-gamma consistently disrupts this epithelial barrier in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::00b535882358bacacfeac3bf30e5be90
https://pubmed.ncbi.nlm.nih.gov/7989770

Enhanced Chemodynamic Therapy Mediated by a Tumor-Specific Catalyst in Synergy with Mitophagy Inhibition Improves the Efficacy for Endometrial Cancer.

Autor: Gong X; Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China.; Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, P. R. China., Wang J; Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China., Yang L; Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China., Li L; Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China., Gao X; Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China., Sun X; Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China., Bai J; Biomedical Instrument Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China., Liu J; State Key Laboratory of Chemical Engineering, School of Chemical Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China., Pu X; State Key Laboratory of Chemical Engineering, School of Chemical Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China., Wang Y; Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China.; Shanghai Municipal Key Clinical Specialty, Female Tumor Reproductive Specialty, Shanghai, 200030, P. R. China.

Publikováno v: Small (Weinheim an der Bergstrasse, Germany) [Small] 2023 Aug; Vol. 19 (33), pp. e2301497. Date of Electronic Publication: 2023 Apr 22.

Elucidation of Protonation Cooperativity of a STING‐Activating Polymer.

Autor: Wang, Maggie, Bennett, Zachary T., Singh, Parnavi, Feng, Qiang, Wilhelm, Jonathan, Huang, Gang, Gao, Jinming

Publikováno v: Advanced Materials; 12/21/2023, Vol. 35 Issue 51, p1-10, 10p

Rapid Interference-free Analysis of β-Lapachone in Clinical Samples Using Liquid Chromatography-Mass Spectrometry for a Pharmacokinetic Study in Humans.

Autor: Kim BK; Department of Molecular Medicine, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, 41944, Korea.; Clinical Omics Institute, School of Medicine, Kyungpook National University, Daegu, 41944, Korea., Gwon MR; Department of Molecular Medicine, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, 41944, Korea.; Clinical Omics Institute, School of Medicine, Kyungpook National University, Daegu, 41944, Korea., Kang WY; Department of Molecular Medicine, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, 41944, Korea., Lee IK; Department of Internal Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, 41944, Korea., Lee HW; Department of Molecular Medicine, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, 41944, Korea., Seong SJ; Department of Molecular Medicine, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, 41944, Korea.; Clinical Omics Institute, School of Medicine, Kyungpook National University, Daegu, 41944, Korea., Cho S; Clinical Omics Institute, School of Medicine, Kyungpook National University, Daegu, 41944, Korea. chosi1@gmail.com., Yoon YR; Department of Molecular Medicine, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, 41944, Korea. yry@knu.ac.kr.; Clinical Omics Institute, School of Medicine, Kyungpook National University, Daegu, 41944, Korea. yry@knu.ac.kr.

Publikováno v: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry [Anal Sci] 2021 Aug 10; Vol. 37 (8), pp. 1105-1110. Date of Electronic Publication: 2020 Dec 25.