Zobrazeno 1 - 10
of 14
pro vyhledávání: '"S M, Hart"'
Autor:
S. W. Mittelstadt, S. M. Hart
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 28:253-256
Moxifloxacin has been shown to induce QT prolongation in both clinical and preclinical models. However, the ability to observe this effect at clinically relevant concentration in normal conscious dogs has not been reported. The purpose of this study
Autor:
L, Buluwela, J, Pike, D, Mazhar, T, Kamalati, S M, Hart, R, Al-Jehani, H, Yahaya, N, Patel, N, Sarwar, N, Sarwarl, D A, Heathcote, O, Schwickerath, F, Phoenix, R, Hill, E, Aboagye, S, Shousha, J, Waxman, N R, Lemoine, A, Zelent, R C, Coombes, S, Ali
Publikováno v:
Gene Therapy. 12:452-460
Estrogen receptor alpha (ERalpha) is a ligand-inducible transcription factor that acts to regulate gene expression by binding to palindromic DNA sequence, known as the estrogen response element, in promoters of estrogen-regulated genes. In breast can
Publikováno v:
Blood. 80:1502-1510
The Ig idiotype of B-cell lymphoma can be used as a tumor-specific target. Prior trials with monoclonal anti-idiotype antibodies alone and combined with alpha-interferon have shown significant antitumor activity. In some patients, idiotype-negative t
Publikováno v:
Anaesthesia and intensive care. 37(6)
Electroencephalogram depth of anaesthesia monitors are increasingly being used, with the aim of reducing awareness during anaesthesia. Most literature concentrates on the ability of these monitors to predict when a patient is likely to be aware. This
Publikováno v:
Experimental hematology. 25(12)
Overexpression of a 110-kD protein (lung resistance-related protein [LRP]) may predict a poor response to chemotherapy in patients with acute myeloid leukemia (AML) and ovarian carcinoma. The LRP gene has recently been mapped to chromosome 16, close
Publikováno v:
Laboratory animal science. 47(3)
Two studies, designed to mimic a single-dose, cross-over pharmacokinetic protocol, were conducted to gain a better understanding of the rat's response to multiple, frequent blood sampling. Parameters evaluated included body weight, clinical signs of
Publikováno v:
Cancer research. 57(5)
The double-stranded RNA (dsRNA)-activated protein kinase (PKR) is one of many genes induced by IFN. The PKR sequentially undergoes autophosphorylation and activation on binding to dsRNA. Previous studies have shown that PKR may be an important factor
Publikováno v:
Leukemia. 8(12)
A semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) was used to investigate and compare transcription levels of the human multidrug resistance gene (MDR1) and the recently described multidrug resistance-associated protein (MR
Autor:
C E, Johnson, S M, Hart
Publikováno v:
American journal of hospital pharmacy. 50(11)
The stability of baclofen in an extemporaneously compounded oral liquid formulation for 35 days was studied. A suspension was prepared by grinding commercially available 20-mg baclofen tablets and adding Glycerin, USP, to form a paste. Simple Syrup,
Autor:
Catherine G. M. Flynn, S. M. Hart
Publikováno v:
Irish journal of medical science. 162(10)
Percutaneous tracheostomy (PCT) facilitates easy, bedside insertion of a tracheostomy tube. The percutaneous approach to tracheostomy is used in some parts of the world. This is the first report of a PCT method, in Ireland. The percutaneous technique