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pro vyhledávání: '"S M, Gagné"'
Publikováno v:
Biochemistry. 36(15)
The structural transition in troponin C induced by the binding of two calcium ions involves an "opening" of the structure, an event that triggers skeletal muscle contraction. We have solved the solution structure of a mutant (E41A) of the regulatory
Autor:
T L, Pauls, I, Durussel, J A, Cox, I D, Clark, A G, Szabo, S M, Gagné, B D, Sykes, M W, Berchtold
Publikováno v:
The Journal of biological chemistry. 268(28)
Rat parvalbumin (PV), an EF-hand type Ca(2+)-binding protein, was expressed in Escherichia coli and mutated by replacing a Phe at position 102 with a unique Trp in order to introduce a distinct fluorescent label into the protein. Mass spectroscopy an