Zobrazeno 1 - 10 of 18 pro vyhledávání: '"S M, Foord"'
1
Amylin receptor phenotypes derived from human calcitonin receptor/RAMP coexpression exhibit pharmacological differences dependent on receptor isoform and host cell environment
Autor: N, Tilakaratne, G, Christopoulos, E T, Zumpe, S M, Foord, P M, Sexton
Publikováno v: The Journal of pharmacology and experimental therapeutics. 294(1)
Receptor activity modifying proteins (RAMPs) constitute a group of three proteins, designated as RAMP1, 2, and 3, which are able to effect functional changes in some members of the G protein-coupled receptor family. Thus, RAMP1 or RAMP3 can modify th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::51733048b5ec26bdbad2a67f0dd97b38
https://pubmed.ncbi.nlm.nih.gov/10871296
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2
GR196429: a nonindolic agonist at high-affinity melatonin receptors
Autor: I J, Beresford, C, Browning, S J, Starkey, J, Brown, S M, Foord, J, Coughlan, P C, North, M L, Dubocovich, R M, Hagan
Publikováno v: The Journal of pharmacology and experimental therapeutics. 285(3)
N-[2-[2,3,7,8-tetrahydro-1H-furo(2,3-g)indol-1-yl]ethyl]acetamide (GR196429) is a novel, nonindolic melatonin receptor agonist. GR196429 had high affinity for human mt1 (pKi 9.9) and MT2 (pKi 9.8) receptors expressed in Chinese hamster ovary cells an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cbd3fec0f94bcc104ac36de58a8b0d42
https://pubmed.ncbi.nlm.nih.gov/9618428
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3
Characterization of [3H]-prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virus
Autor: F H, Marshall, K, Patel, K, Lundstrom, J, Camacho, S M, Foord, M G, Lee
Publikováno v: British journal of pharmacology. 121(8)
1. The human prostaglandin EP4 receptor has been expressed by use of the Semliki Forest virus system. 2. In cell membranes [3H]-prostaglandin E2 ([3H]-PGE2) bound to a high affinity site with a Kd of 1.12 +/- 0.3 nM and a Bmax of 3.1 +/- 0.3 pmol mg-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d172ea95ec35d4b920e6d4f39976ea8
https://pubmed.ncbi.nlm.nih.gov/9283702
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5
Exaggerated Circadian Variation in Basal Thyrotropin (TSH) and in the Dopaminergic Inhibition of TSH Release in Pathological Hyperprolactinemia: Evidence Against a Hypothalamic Dopaminergic Defect
Autor: John R. Peters, M. D. Rodriguez-Arnao, Reginald Hall, A. Gomez-Pan, Carlos Dieguez, Robert G. Newcombe, S. M. Foord, Maurice F. Scanlon, C. Edwards
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 57:975-980
In order to delineate more accurately the dopaminergic control of anterior pituitary function in normal subjects and in patients with pathological hyperprolactinemia, we investigated the nature of the circadian variation in the dopaminergic inhibitio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120ea612b5bcbb9b4fce2af2967f0abe
https://doi.org/10.1210/jcem-57-5-975
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6
THE INFLUENCE OF OESTROGENS ON THE SENSITIVITY OF PRL, TSH AND LH TO THE INHIBITORY ACTIONS OF DOPAMINE IN HYPERPROLACTINAEMIC PATIENTS
Autor: R. Hall, R. Valcavi, John R. Peters, S. M. Foord, P. J. Evans, P. E. Harris, C. Dieguez, Maurice F. Scanlon
Publikováno v: Clinical Endocrinology. 23:139-146
SUMMARY The effects of oestrogen priming on the response of serum PRL, LH and TSH to dopamine (DA) infusion have been studied in hyperprolactinaemia. Seven hyperprolactinaemic females (aged 22–57 years; basal PRL 911–5130 mU/1, normal >420 mU/1),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa31ba4a8cae4751363410e9b69d03b
https://doi.org/10.1111/j.1365-2265.1985.tb00208.x
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7
RELATIONSHIPS BETWEEN THE CIRCADIAN RHYTHMS OF TSH, PROLACTIN AND CORTISOL IN SURGICALLY TREATED MICROPROLACTINOMA PATIENTS
Autor: S. M. Foord, John R. Peters, C. Dieguez, C. Edwards, P. E. Harris, Maurice F. Scanlon, J. Salvador, D. W. Wilson, R. Hall
Publikováno v: Clinical Endocrinology. 22:265-272
Pharmacological doses of glucocorticoids inhibit TSH release both in vivo and in vitro and since the circadian rhythms of TSH and cortisol show a reciprocal relationship, the hypothesis has been advanced that changes in cortisol levels may be a prima
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b441a9cb226b277431ab8aee4c583e
https://doi.org/10.1111/j.1365-2265.1985.tb03239.x
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8
Growth hormone responses to growth hormone-releasing factor (1–29) in euthyroid, hypothyroid and hyperthyroid rats
Autor: Randolph W. Hall, A. Gomez-Pan, S. M. Foord, V. Jordan, P. E. Harris, Carlos Dieguez, Maurice F. Scanlon, M. D. Rodriguez-Arnao
Publikováno v: Journal of Endocrinology. 109:53-56
In order to investigate whether the impaired GH secretion associated with hypothyroidism and hyperthyroidism is due to a hypothalamic or a pituitary disorder, we have studied plasma GH responses to GH-releasing factor (1–29) (GRF) in euthyroid, hyp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523c9ee3361606fba6a2d3156d376912
https://doi.org/10.1677/joe.0.1090053
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9
Alpha 1-adrenoreceptors and alpha 1-adrenoreceptor-mediated thyrotropin release in cultures of euthyroid and hypothyroid rat anterior pituitary cells
Autor: Maurice F. Scanlon, S. M. Foord, C. Dieguez, John R. Peters, Reginald Hall
Publikováno v: Endocrinology. 117(2)
TSH responses to adrenergic agonists have been measured in 3-day monolayer cultures of euthyroid and hypothyroid male rat anterior pituitary (AP) cells. Responses were qualitatively similar in that (-)epinephrine and (-)norepinephrine had the same ED
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e732ed974e16afd995501f518ec669
https://pubmed.ncbi.nlm.nih.gov/2990855
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10
Thyrotropin regulates thyrotroph responsiveness to dopamine in vitro
Autor: John R. Peters, Reginald Hall, Gerald Shewring, C. Dieguez, S. M. Foord, Maurice F. Scanlon
Publikováno v: Endocrinology. 118(4)
The effect of conditioned vs. fresh culture medium on the dopaminergic inhibition of TSH and PRL secretion by primary cultures of male rat anterior pituitary cells has been studied. In the presence of conditioned medium (that had been in contact with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238de3b077015e57db12c95c8bf9bd04
https://pubmed.ncbi.nlm.nih.gov/3004910
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