Zobrazeno 1 - 10
of 48
pro vyhledávání: '"S M, Deyev"'
Autor:
O. V. Shlepova, M. A. Shulepko, V. O. Shipunova, M. L. Bychkov, I. D. Kukushkin, I. A. Chulina, V. N. Azev, E. I. Shramova, V. A. Kazakov, A. M. Ismailova, Y. A. Palikova, V. A. Palikov, E. A. Kalabina, E. A. Shaykhutdinova, G. A. Slashcheva, E. A. Tukhovskaya, I. A. Dyachenko, A. N. Murashev, S. M. Deyev, M. P. Kirpichnikov, Z. O. Shenkarev, E. N. Lyukmanova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
α7-Type nicotinic acetylcholine receptor (α7-nAChR) promotes the growth and metastasis of solid tumors. Secreted Ly6/uPAR-Related Protein 1 (SLURP-1) is a specific negative modulator of α7-nAChR produced by epithelial cells. Here, we investigated
Externí odkaz:
https://doaj.org/article/68ca419785d04cd79f6b4a41671b974e
Publikováno v:
Бюллетень сибирской медицины, Vol 21, Iss 4, Pp 6-12 (2023)
Aim. To determine informative prognostic criteria for assessing the HER2 / neu status in primary breast cancer using 99mTc-DARPinG3.Materials and methods. The study included 10 patients with breast cancer (T1-4N0-2M0) before systemic therapy, who und
Externí odkaz:
https://doaj.org/article/2dd19183a22944f5adfe4037be6d64d7
Publikováno v:
Бюллетень сибирской медицины, Vol 21, Iss 3, Pp 132-139 (2022)
HER2-positive breast cancer occurs in 15–20% of breast cancer patients and is associated primarily with a poor prognosis of the disease and the need for highly specific targeted therapy. Despite the clinical importance of determining HER2/neu, trad
Externí odkaz:
https://doaj.org/article/141f865557d04efd9bc5529ae83e4e99
Autor:
O. D. Bragina, V. I. Chernov, A. A. Medvedeva, R. V. Zelchan, M. S. Larkina, S. M. Deyev, V. M. Tolmachev
Publikováno v:
Сибирский научный медицинский журнал, Vol 40, Iss 4, Pp 35-43 (2020)
Epidermal growth receptor HER2/neu is still of great interest, the overexpression of which is most often observed in patients with breast cancer and accounts for 15–20 % of cases. Present methods of HER2/neu determination have a number of significa
Externí odkaz:
https://doaj.org/article/109451c7793b49958642cfab5ea001b7
Autor:
R. S. Kalinin, V. O. Shipunova, Y. P. Rubtsov, V. M. Ukrainskay, A. Schulga, E. V. Konovalova, D. V. Volkov, I. A. Yaroshevich, A. M. Moysenovich, A. A. Belogurov, G. B. Telegin, A. S. Chernov, M. A. Maschan, S. S. Terekhov, V. D. Knorre, E. Khurs, N. V. Gnuchev, A. G. Gabibov, S. M. Deyev
Publikováno v:
Doklady Biochemistry and Biophysics. 508:17-20
Abstract The development of CAR-T specific therapy made a revolution in modern oncology. Despite the pronounced therapeutic effects, this novel approach displayed several crucial limitations caused by the complications in pharmacokinetics and pharmac
Autor:
I. V. Balalaeva, L. V. Krylova, M. A. Karpova, A. A. Shulga, E. V. Konovalova, E. L. Guryev, S. M. Deyev
Publikováno v:
Doklady Biochemistry and Biophysics. 507:330-333
Autor:
I V, Zelepukin, I N, Ivanov, A B, Mirkasymov, K G, Shevchenko, A A, Popov, P N, Prasad, A V, Kabashin, S M, Deyev
Publikováno v:
Journal of Controlled Release
Journal of Controlled Release, 2022, 349, pp.475-485. ⟨10.1016/j.jconrel.2022.07.007⟩
Journal of Controlled Release, 2022, 349, pp.475-485. ⟨10.1016/j.jconrel.2022.07.007⟩
Bismuth-based compounds are considered to be the best candidates for computed tomography (CT) imaging of gastrointestinal (GI) tract due to high X-ray absorption. Here, we report the introduction of polymer-coated bismuth oxychloride (BiOCl) nanoshee
Publikováno v:
Acta Naturae. 14:4-15
This review examines the evolution of the radionuclide diagnosis of HER2-positive breast cancer using various compounds as a targeting module in clinical practice: from full-length antibodies to a new group of small synthetic proteins called alternat
Autor:
V O, Shipunova, S M, Deyev
Publikováno v:
Acta Naturae. 14:54-72
The use of traditional tools for the targeted delivery of nanostructures, such as antibodies, transferrin, lectins, or aptamers, often leads to an entire range of undesirable effects. The large size of antibodies often does not allow one to reach the
Autor:
E. I. Shramova, M. V. Shilova, G. M. Proshkina, Victoria O. Shipunova, Alexey A. Schulga, S. M. Deyev
Publikováno v:
Russian Journal of Bioorganic Chemistry. 46:1156-1161
In this work for the first time we demonstrate the possibility of ribonuclease barnase delivery to HER2-positive human cancer cells in a liposomal form. The principle of loading liposomes with ribonuclease is based on the electrostatic interaction of