Zobrazeno 1 - 10
of 23
pro vyhledávání: '"S M, D'Ambrosio"'
Publikováno v:
Cell Biology and Toxicology. 9:385-403
The use of normal adult liver hepatocytes in cell culture for biochemical, toxicological and pharmacological studies has been greatly limited owing to the loss of replicative capacity and differentiated liver function. This is contrary to the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6f5d026f349a58582e2eb5a46384da
https://doi.org/10.1007/bf00754467
https://doi.org/10.1007/bf00754467
Autor:
S M, D'Ambrosio, R E, Gibson-D'Ambrosio, G, Wani, B, Casto, G E, Milo, G J, Kelloff, V E, Steele
Publikováno v:
Anticancer research. 21(5)
Aberrant expression of Ki67, p53 and RARbeta are characteristic of many tumor types including those of the oral cavity. Chemopreventive agents may act by modulating their expression to more normal levels.The effects of 21 chemopreventive agents on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c7f28dfc4d33c8c6390fee826c37dc3
https://pubmed.ncbi.nlm.nih.gov/11848477
https://pubmed.ncbi.nlm.nih.gov/11848477
Publikováno v:
Environmental and molecular mutagenesis. 37(1)
Chronic exposure of hepatocytes to reactive nitrogen species (RNS) following liver injury and inflammation leads not only to functional and morphological alterations in the liver but also to degenerative liver diseases and hepatocellular carcinoma. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9185d7cdc2a3b74381392012cdb0dc4
https://pubmed.ncbi.nlm.nih.gov/11170241
https://pubmed.ncbi.nlm.nih.gov/11170241
Publikováno v:
Anticancer research. 20(4)
Squamous cell carcinoma (SCC) of the oral cavity is a multistep process, progressing through a series of discrete, irreversible and complementary alterations in genes that control cell growth, death, and differentiation. In the premalignant state, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ddedde5973c5ea6a9c57ad15e114566
https://pubmed.ncbi.nlm.nih.gov/10953285
https://pubmed.ncbi.nlm.nih.gov/10953285
Autor:
G, Wani, S M, D'Ambrosio
Publikováno v:
Anticancer research. 17(6D)
In tumors, resistance to chemotherapeutic drugs that alkylate the O6 position of guanine correlates with the levels of the DNA repair protein, O6-alkylguanine DNA alkyltransferase (AGT). The expression of AGT gene in human breast tumors was evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::545dc797c61d4514ee2e377f798c634b
https://pubmed.ncbi.nlm.nih.gov/9494526
https://pubmed.ncbi.nlm.nih.gov/9494526
Publikováno v:
Molecular medicine (Cambridge, Mass.). 3(4)
BACKGROUND: The overexpression or amplification of tumor suppressor and proto-oncogenes are important factors in the progression of breast cancer. Recent attention has focused on the cyclin genes, whose involvement in signal transduction pathways reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9585c94c961a2cea293f20f30a6e0048
https://pubmed.ncbi.nlm.nih.gov/9131589
https://pubmed.ncbi.nlm.nih.gov/9131589
Publikováno v:
Cancer letters. 112(1)
6-Phenylhexyl isothiocyanate (PHITC) enhances esophageal tumorigenesis induced by the carcinogen N -nitrosomethylben-zylamine (NMBA) in rats while its shorter chain analog, phenethyl isothiocyanate (PEITC), inhibits NMBA-induced esophageal tumorigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4590f1849f29a1a60b0efd6f280bc03
https://pubmed.ncbi.nlm.nih.gov/9029177
https://pubmed.ncbi.nlm.nih.gov/9029177
Publikováno v:
Basic life sciences. 53
The capacity of a cell to repair damage is the first step in preventing the deleterious consequences of DNA structural alterations induced by the exposure to mutagenic carcinogens. Mammalian cells, having complex genetic organization, have evolved so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e69c6948b418d9611ff02395b50fa36e
https://pubmed.ncbi.nlm.nih.gov/2282047
https://pubmed.ncbi.nlm.nih.gov/2282047
Publikováno v:
Basic life sciences. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6561b7be2ef8ecb8e572343f3f18a39a
https://pubmed.ncbi.nlm.nih.gov/2282046
https://pubmed.ncbi.nlm.nih.gov/2282046
Publikováno v:
Cancer research. 43(12 Pt 1)
DNA excision repair was measured in cell cultures derived from human fetal brain, intestine, kidney, liver, and skin following ultraviolet (UV) irradiation and N-ethyl-N-nitrosourea (ENU) treatment. Cells in early passages were exposed to 5 or 10 J o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48f500a78ff1353adb37346593df6894
https://pubmed.ncbi.nlm.nih.gov/6640535
https://pubmed.ncbi.nlm.nih.gov/6640535