Výsledky vyhledávání - "S M, Curristin"

Regulation of cystic fibrosis transmembrane conductance regulator (CFTR) gene transcription and alternative RNA splicing in a model of developing intestinal epithelium

Autor: C, Montrose-Rafizadeh, D L, Blackmon, A, Hamosh, M M, Oliva, A L, Hawkins, S M, Curristin, C A, Griffin, V W, Yang, W B, Guggino, G R, Cutting

Publikováno v: The Journal of biological chemistry. 267(27)

Transcriptional and post-transcriptional regulation of CFTR (cystic fibrosis transmembrane conductance regulator) gene expression was studied in HT29 cells. It is known that the abundance of CFTR mRNA increases during differentiation of pluripotent H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48d4502bf15faedcbeafd7ae0c0e0ffe
https://pubmed.ncbi.nlm.nih.gov/1382071

Zobrazit plný text záznamu

Extensive posttranscriptional deletion of the coding sequences for part of nucleotide-binding fold 1 in respiratory epithelial mRNA transcripts of the cystic fibrosis transmembrane conductance regulator gene is not associated with the clinical manifestations of cystic fibrosis

Autor: S. M. Curristin, Chin-Shyan Chu, Ronald G. Crystal, Bruce C. Trapnell, G. R. Cutting

Cystic fibrosis (CF) is a recessive hereditary disorder, requiring both parental cystic fibrosis conductance transmembrane regulator (CFTR) genes to carry mutations for clinical disease to manifest, i.e., only 50% of normal CFTR gene expression is re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc83ba685f355b69347c73c77618ee14
https://europepmc.org/articles/PMC329931/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání