Endotoxin induces downregulation of tumor necrosis factor receptors on circulating monocytes and granulocytes in humans

Autor: Stephen F. Lowry, C. C. Braxton, K. Barbosa, T van der Poll, Steven E. Calvano, L. L. Moldawer, S. M. Coyle, Ashwini Kumar

Publikováno v: Blood, 86(7), 2754-2759. American Society of Hematology

Leukocytes rapidly lose their surface receptors for tumor necrosis factor (TNF) after exposure to various stimuli in vitro. To assess the effect of endotoxin on cellular TNF receptors in humans in vivo, binding of biotinylated TNF to circulating mono

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4e15bd8beee72ba4aa6139ce5af362
https://doi.org/10.1182/blood.v86.7.2754.2754

Parenteral nutrition alters monocyte TNF receptor activity

Autor: S. M. Coyle, C. C. Braxton, Stephen F. Lowry, T. van der Poll, M. Roth, Steven E. Calvano, W. J. Montegut

Publikováno v: Journal of surgical research, 59(1), 23-28. Academic Press Inc.

The route of nutrient provision has been reported to influence some aspects of the host inflammatory response in both patient populations and normal subjects. The tumor necrosis factor receptor system is a complex regulatory mechanism that modulates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41e8c2b0c6d553e52e307f8a43538d8
https://doi.org/10.1006/jsre.1995.1127

Approaching the millennium. How can Catholic healthcare best celebrate the 'Year of the Lord's Favor'?

Autor: S M, Coyle

Publikováno v: Health progress (Saint Louis, Mo.). 80(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7506357bd27648fd0132a59117ee7f6c
https://pubmed.ncbi.nlm.nih.gov/10345102

Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans

Autor: T, van der Poll, S M, Coyle, M, Levi, P M, Jansen, M, Dentener, K, Barbosa, W A, Buurman, C E, Hack, J W, ten Cate, J M, Agosti, S F, Lowry

Publikováno v: Blood. 89(10)

To determine the role of tumor necrosis factor (TNF) in lipopolysaccharide (LPS)-induced inflammation, 12 healthy subjects received an intravenous injection with LPS (2 ng/kg) preceded by infusion of either a recombinant human dimeric TNF receptor ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0957419fef8939b8184454404b0ee401
https://pubmed.ncbi.nlm.nih.gov/9160678

Epinephrine exerts anticoagulant effects during human endotoxemia

Autor: S. F. Lowry, S. M. Coyle, W. A. Buurman, Marcel Levi, J W ten Cate, T van der Poll, M. Dentener, C. E. Hack, P. M. Jansen, C.C. Braxton

Publikováno v: Journal of Experimental Medicine, 185, 1143-1148. Rockefeller University Press
The Journal of Experimental Medicine
Journal of experimental medicine, 185(6), 1143-1148. Rockefeller University Press

To determine the effect of a physiologically relevant elevation in the plasma concentrations of epinephrine on the activation of the hemostatic mechanism during endotoxemia, 17 healthy men were studied after intravenous injection of lipopolysaccharid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9075f05cde4b02e817197018b89ea9
https://dare.uva.nl/personal/pure/en/publications/epinephrine-exerts-anticoagulant-effects-during-human-endotoxemia(1b5d9947-9db4-414b-9588-d48b682e67ad).html