Zobrazeno 1 - 10
of 46
pro vyhledávání: '"S M, Colegate"'
Autor:
P. R. Dorling, S. M. Colegate
Publikováno v:
Handbook of Plant and Fungal Toxicants ISBN: 9780429281952
Complete hydrogen saturation of the indolizine system produces the indolizidine (octahydroindolizine) heterocyclic ring system. Swainsonine, the first water-soluble, polyhydroxylated indolizidine to be reported, was first isolated from, and named aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a50d6898abc14a62c01d7dc90f5d24
https://doi.org/10.1201/9780429281952-1
https://doi.org/10.1201/9780429281952-1
Autor:
M. F. Comber, J. R. Cannon, Melvyn V. Sargent, Alicia M. Aguinaldo, J. A. Armstrong, N. G. Marchant, S. M. Colegate
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a1005d1737fc32fc8c31fe0aedf5125
https://doi.org/10.1002/chin.199633244
https://doi.org/10.1002/chin.199633244
Publikováno v:
Phytochemistry. 31:2123-2126
Tepanone, (2E)-1-phenyl-3-(2-hydroxy-3,4,6-trimethoxyphenyl)prop-2-enone was isolated from roots and stembark of Ellipeia cuneifolia. The structure was deduced from spectroscopic data and confirmed by synthesis of the methylated derivative, methyltep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0bb9da899ceca843de6f19051a40261
https://doi.org/10.1016/0031-9422(92)80377-q
https://doi.org/10.1016/0031-9422(92)80377-q
The aim of this study was to determine the minimum single, intra-duodenal dose of tunicamycins that would significantly alter serum biochemistry (liver enzymes, albumin, total protein and total bilirubin) but would not induce overt clinical signs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88bf4036d1920285fbe097b50e24947e
https://doi.org/10.1079/9781845932732.0242
https://doi.org/10.1079/9781845932732.0242
To find out the toxic effect of Cynosurus echinatus related Drechslera biseptata on cattle, cultures of D. biseptata isolated from outbreaks of acute bovine liver disease (ABLD) were preserved and tested on cultured rat hepatocytes. Results showed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a8e03dcd5e4cd024e09cdc95be189d5
https://doi.org/10.1079/9781845932732.0107
https://doi.org/10.1079/9781845932732.0107
Autor:
N. Anderton, Y. Cao, C. Darcy, M. Ford, J. Greenwood, A. Knill, A. Michalewicz, P. L. Stewart, S. Wilson, S. M. Colegate
Eight studies were conducted to determine the weight-related effects and feed intake levels for rats and sheep given tunicamycin (TMs) as single parenteral doses or exposed to different levels of dietary TMs for varying lengths of time: 75 and 300 µ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baad31778e7a6ea53704c8a42704ee8f
https://doi.org/10.1079/9781845932732.0235
https://doi.org/10.1079/9781845932732.0235
The solid phase extraction of the aqueous acid solubles of methanolic extracts of Echium plantagineum provided an alkaloidal fraction that was analysed using high pressure liquid chromatography (HPLC) coupled to ion trap, electrospray ionization mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd55fdc6c15184a51d95dfc6329792b1
https://doi.org/10.1079/9781845932732.0481
https://doi.org/10.1079/9781845932732.0481
Autor:
J. G. Allen, M. Retallick, M. Kowalski, S. M. Colegate, E. J. Speijers, T. Doran, W. Michalski
The effects of corynetoxins (from Lolium rigidum) and tunicamycins on hepatocyte viability and morphology were indistinguishable providing further evidence that these 2 related toxins have equivalent bioactivity and continue to support use of the tun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74271fa4a9eb41a27d1a47cd78eee435
https://doi.org/10.1079/9781845932732.0504
https://doi.org/10.1079/9781845932732.0504
An experiment was conducted to produce antibodies that could be used in an ELISA format to detect the parent pyrrolizidine alkaloids and their N-oxides of H. europaeum simultaneously. The cross-reactivity of various pyrrolizidine alkaloids and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f9e068d669bc244a7d20a55e5fa935a
https://doi.org/10.1079/9781845932732.0476
https://doi.org/10.1079/9781845932732.0476
To further investigate the effects of tunicamycins (TMs) at the molecular level, a toxicogenomic approach was developed to examine the differential gene expression between cultured rat hepatocytes exposed to TMs at low levels and untreated cultured h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9b6fd9c9c615d15a0c2e196f622554d
https://doi.org/10.1079/9781845932732.0253
https://doi.org/10.1079/9781845932732.0253