Zobrazeno 1 - 10
of 18
pro vyhledávání: '"S M, Chuva De Sousa Lopes"'
Autor:
X. Fan, M. Bialecka, I. Moustakas, E. Lam, V. Torrens-Juaneda, N. V. Borggreven, L. Trouw, L. A. Louwe, G. S. K. Pilgram, H. Mei, L. van der Westerlaken, S. M. Chuva de Sousa Lopes
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
In the ovary, follicular degeneration occurs after folliculogenesis, with one dominant follicle reaching maturity every month. Here, by performing single cell RNA-seq of adult human follicles, the authors identify subclasses of granulosa and theca ce
Externí odkaz:
https://doaj.org/article/a7401d07ed204ad8a215860ccf7392d9
Autor:
A Christodoulaki, H He, M Zhou, A Cardona Barberán, C De Roo, S M Chuva De Sousa Lopes, M Baetens, B Menten, A Van Soom, P De Sutter, S Weyers, A Boel, D Stoop, B Heindryckx
Publikováno v:
Human Reproduction.
STUDY QUESTION Can spindle transfer (ST) overcome inferior embryonic development of in vitro matured ovarian tissue oocytes (OTO-IVM) originating from testosterone-treated transgender men? SUMMARY ANSWER ST shows some potential to overcome the embryo
Autor:
P Stamatiadis, G Cosemans, A Boel, B Menten, P De Sutter, D Stoop, S M Chuva de Sousa Lopes, F Lluis, P Coucke, B Heindryckx
Publikováno v:
Human Reproduction, 37(8), 1760-1773. OXFORD UNIV PRESS
STUDY QUESTION What is the role of transcriptional-enhanced associate (TEA) domain family member 4 (TEAD4) in trophectoderm (TE) differentiation during human embryo preimplantation development in comparison to mouse? SUMMARY ANSWER TEAD4 regulates TE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185db8cde6b809c0b3cba81558d9a8a3
https://hdl.handle.net/1887/3563156
https://hdl.handle.net/1887/3563156
Autor:
Paul Coucke, Petra De Sutter, Bieke Bekaert, Björn Heindryckx, Björn Menten, Annekatrien Boel, S M Chuva de Sousa Lopes, Panagiotis Stamatiadis, Dominic Stoop, Mina Popovic
Publikováno v:
Human Reproduction. 36
Study question Can clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing result in the correction of a single base pair substitution that causes male infertility? Summary answer CRISPR/Cas9 administration during intracy
Autor:
D Stoop, Annekatrien Boel, Björn Menten, G Cosemans, Panagiotis Stamatiadis, Frederic Lluis, P. De Sutter, F. Van Nieuwerburgh, S M Chuva de Sousa Lopes
Publikováno v:
Human Reproduction. 36
Study question What is the main pathway regulating trophectoderm (TE) differentiation during pre-implantation development in mouse versus human embryos? Summary answer TEAD4 is acting upstream of CDX2 and is involved in TE differentiation, as TEAD4-n
Autor:
Paul Coucke, D Stoop, P. De Sutter, Ramesh Reddy Guggilla, F. Van Nieuwerburgh, Björn Heindryckx, S M Chuva de Sousa Lopes, Mao-Xing Tang, Annekatrien Boel, Bieke Bekaert, Björn Menten, G Cosemans, Panagiotis Stamatiadis, Mina Popovic
Publikováno v:
None
STUDY QUESTION What is the role of POU class 5 homeobox 1 (POU5F1) in human preimplantation development and how does it compare with the mouse model? SUMMARY ANSWER POU5F1 is required for successful development of mouse and human embryos to the blast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872f1a86a8c5a728777275d58698030c
https://hdl.handle.net/1887/3280153
https://hdl.handle.net/1887/3280153
Autor:
Dieter De Coninck, A. Van Soom, Mina Popovic, E Sutherland, Björn Heindryckx, J Van de Sompele, M Van der Jeught, Laurentijn Tilleman, G Duggal, P. De Sutter, S M Chuva de Sousa Lopes, Jasin Taelman, Pieter Mestdagh, Sylvie Lierman, Björn Menten, Dieter Deforce, F. Van Nieuwerburgh, Luc Peelman, Sharat Warrier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
NATURE COMMUNICATIONS
Nature Communications, 8
Nature Communications
NATURE COMMUNICATIONS
Nature Communications, 8
Until recently, human embryonic stem cells (hESCs) were shown to exist in a state of primed pluripotency, while mouse embryonic stem cells (mESCs) display a naive or primed pluripotent state. Here we show the rapid conversion of in-house-derived prim
Autor:
Jon D. Laman, Nieske Brouwer, Susanne M. Kooistra, Laura Kracht, Sharon Eskandar, Jelmer R. Prins, Sicco A. Scherjon, S M Chuva de Sousa Lopes, Bart J. L. Eggen, Malte Borggrewe
Publikováno v:
Science, 369(6503), 530-+. AMER ASSOC ADVANCEMENT SCIENCE
Science, 369(6503), 530-537. AMER ASSOC ADVANCEMENT SCIENCE
Science, 369(6503), 530-537. AMER ASSOC ADVANCEMENT SCIENCE
The development of microglia Microglia are the brain's immune cells, and they play important roles in health and neurodegenerative disease. Kracht et al. performed single-cell analysis of human microglial gene expression and chromatin accessibility a
Autor:
Mina Popovic, P. De Sutter, Annelies Dheedene, Lien Dhaenens, Björn Menten, Monika Bialecka, Jasin Taelman, Björn Heindryckx, S M Chuva de Sousa Lopes
Publikováno v:
Human Reproduction, 34(4), 758-769
STUDY QUESTION What is the accuracy of preimplantation genetic testing for aneuploidies (PGT-A) when considering human peri-implantation outcomes in vitro? STUDY ANSWER The probability of accurately diagnosing an embryo as abnormal was 100%, while th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e25621d26532431b76d9e3658e58ff7
https://hdl.handle.net/1887/120527
https://hdl.handle.net/1887/120527
Autor:
Hailiang Mei, Vanessa Torrens-Juaneda, Monika Bialecka, Eric Lam, Ioannis Moustakas, N. V. Borggreven, L. A. Louwe, L. van der Westerlaken, S M Chuva de Sousa Lopes, Gonneke S. K. Pilgram, Xueying Fan, L. Trouw
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS
Nature Communications, 10
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
NATURE COMMUNICATIONS
Nature Communications, 10
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The ovary is perhaps the most dynamic organ in the human body, only rivaled by the uterus. The molecular mechanisms that regulate follicular growth and regression, ensuring ovarian tissue homeostasis, remain elusive. We have performed single-cell RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c281b8ff8d7fd5763ea511f754f307fc
https://hdl.handle.net/1887/120067
https://hdl.handle.net/1887/120067