Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S M, Burris"'
Publikováno v:
The Journal of laboratory and clinical medicine. 120(5)
Mild thrombocytopenia is common in alcoholic individuals. Ethanol appears to impair platelet production primarily by affecting the maturing megakaryocyte compartment. We recently showed that guinea pigs have an unusually large number of elongated pla
Publikováno v:
American journal of veterinary research. 53(11)
The effects of furosemide and pentoxifylline on blood flow properties in horses were investigated. Hematologic and rheologic changes were examined in 4 horses before and 3 minutes after administration of epinephrine (1 mg, IV). The next day, hemorheo
Publikováno v:
The Journal of laboratory and clinical medicine. 115(6)
Elongated cylindric and beaded platelet forms are infrequently observed in the circulation, and have been termed "proplatelets," as presumed precursors to discoid platelets. Some 15% of the blood platelets obtained from the guinea pig by cardiac punc
Publikováno v:
The Journal of laboratory and clinical medicine. 96(4)
The intrusion of micromolar amounts of calcium into the calcium-poor interior of the human erythrocyte initiates a series of cataclysmic changes in cellular metabolism and morphology. These include (1) cellular shrinkage (elevated mean cell hemoglobi
Micropipette aspiration of human platelets: influence of rewarming on deformability of chilled cells
Publikováno v:
The Journal of laboratory and clinical medicine. 107(3)
Recent studies using micropipette elastimetry have shown that the circumferential microtubule supporting the discoid form of resting platelets has a direct influence on the resistance of the cell to deformation. However, the findings did not resolve
Publikováno v:
Blood. 73(6)
Platelet release has been alternatively viewed as a fragmentation of platelet territories demarcated within the cytoplasm of mature megakaryocytes or as a later event involving segmentation of proplatelet pseudopodia extended from the cell. The mecha
Publikováno v:
American journal of veterinary research. 50(1)
We evaluated the deformability of bovine platelets and contrasted the effects of pharmacologic and thermal perturbations on cytoskeletal structure of human and bovine platelets. Platelets were aspirated into micropipettes (0.7 to 0.8 micron in diamet
Publikováno v:
The American journal of pathology. 125(2)
The discoid shape of human blood platelets is supported by a circumferential microtubule (MT) organized in many loops or coils. A recent study reported from the authors' laboratory demonstrated that significant numbers of MT rings could be isolated f
Publikováno v:
Blood. 58(1)
The relationship of altered deformability of irreversibly sickled cells (ISC) to their morphological and physiologic characteristics was evaluated in this study. ISC obtained by differential centrifugation and density gradient sedimentation were sepa
Publikováno v:
Blood. 63(5)
Previous reports have suggested that platelets from patients with Bernard-Soulier's syndrome (BSS) are not giant cells. Rather, they are normal-sized in suspension, but spread out on glass slides more readily than control cells, yielding the impressi