Zobrazeno 1 - 10
of 174
pro vyhledávání: '"S M, Bromidge"'
Publikováno v:
Synthetic Communications. 23:487-494
The controlled addition of nucleophiles to (trimethylsilyl) ethynyl ketones provides a facile route to β-ketoacetals, β-alkoxy-α,β-unsaturated ketones or vinylogous amides depending on the choice of reaction conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f310a386f4522c6de82adea5ecb963b2
https://doi.org/10.1080/00397919308009803
https://doi.org/10.1080/00397919308009803
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d6e860122f0d30be999315be6f8b85
https://doi.org/10.1002/chin.199414064
https://doi.org/10.1002/chin.199414064
Autor:
W D, Hirst, J A, Minton, S M, Bromidge, S F, Moss, A J, Latter, G, Riley, C, Routledge, D N, Middlemiss, G W, Price
Publikováno v:
British journal of pharmacology. 130(7)
SB-258585 (4-Iodo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzen esulphonamide) is a high affinity ligand at 5-HT(6) receptors. It displays over 100 fold selectivity for the 5-HT(6) receptor over all other 5-HT receptors tested so far. SB-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee675bb6fc0eb47608d85ac710828b99
https://pubmed.ncbi.nlm.nih.gov/10928963
https://pubmed.ncbi.nlm.nih.gov/10928963
Autor:
J J, Hagan, G W, Price, P, Jeffrey, N J, Deeks, T, Stean, D, Piper, M I, Smith, N, Upton, A D, Medhurst, D N, Middlemiss, G J, Riley, P J, Lovell, S M, Bromidge, D R, Thomas
Publikováno v:
British journal of pharmacology. 130(3)
The novel 5-HT(7) receptor antagonist, SB-269970-A, potently displaced [(3)H]-5-CT from human 5-HT(7(a)) (pK(i) 8.9+/-0.1) and 5-HT(7) receptors in guinea-pig cortex (pK(i) 8.3+/-0.2). 5-CT stimulated adenylyl cyclase activity in 5-HT(7(a))/HEK293 me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2fba9af73cfc119fddf16ee0f070d70
https://pubmed.ncbi.nlm.nih.gov/10821781
https://pubmed.ncbi.nlm.nih.gov/10821781
Autor:
D R, Thomas, P J, Atkinson, M, Ho, S M, Bromidge, P J, Lovell, A J, Villani, J J, Hagan, D N, Middlemiss, G W, Price
Publikováno v:
British journal of pharmacology. 130(2)
Binding of the 5-HT(7) receptor antagonist radioligand [(3)H]-SB-269970 to human 5-HT(7(a)) receptors expressed in HEK293 cell membranes (h5-HT(7(a))/293) and to guinea-pig cerebral cortex membranes, was characterized and compared with [(3)H]-5-CT bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb9bed005eacd21675947e60545ca6bf
https://pubmed.ncbi.nlm.nih.gov/10807680
https://pubmed.ncbi.nlm.nih.gov/10807680
Autor:
J M, Loudon, S M, Bromidge, F, Brown, M S, Clark, J P, Hatcher, J, Hawkins, G J, Riley, G, Noy, B S, Orlek
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(3)
The finding that ascending cholinergic systems are severely degenerated in Alzheimer's disease has driven the search for a cholinomimetic therapy. Adverse effects observed with cholinesterase inhibitors and high-efficacy muscarinic agonists led us to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b42546b9eda390cfeee3e533081b65e
https://pubmed.ncbi.nlm.nih.gov/9399977
https://pubmed.ncbi.nlm.nih.gov/9399977
Autor:
Dorababu, Atukuri1 (AUTHOR)
Publikováno v:
Polycyclic Aromatic Compounds. 2023, Vol. 43 Issue 3, p2250-2268. 19p.
Publikováno v:
Chemischer Informationsdienst. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad9642f0d3704ab0aa48c5658b6c9e9c
https://doi.org/10.1002/chin.198549290
https://doi.org/10.1002/chin.198549290
Autor:
Srinivasulu, A.1,2 (AUTHOR), Vani, D.1,2 (AUTHOR), Kumar, G. Sathish1 (AUTHOR), Shantharjun, B.1,2 (AUTHOR), Chahal, Kapil1,2 (AUTHOR), Sridhar, Balasubramanian2,3 (AUTHOR), Reddy, K. Rajender1,2 (AUTHOR) rajender@iict.res.in
Publikováno v:
Advanced Synthesis & Catalysis. 4/12/2022, Vol. 364 Issue 8, p1415-1421. 7p.
Autor:
Kim, Doyoung1,2 (AUTHOR), Lee, Jieon1,3 (AUTHOR), Kwag, Rina1,4 (AUTHOR), Kim, Hyunbin1,3 (AUTHOR), Oh, Hyunji1,2 (AUTHOR), Moon, Bongjin2 (AUTHOR), Kim, Hak Joong4 (AUTHOR), Seong, Jihye1,3 (AUTHOR), Jeon, Byungsun1 (AUTHOR), Kang, Taek1 (AUTHOR) tkang@kist.re.kr, Choo, Hyunah1,3 (AUTHOR) hchoo@kist.re.kr
Publikováno v:
Bulletin of the Korean Chemical Society. Jan2022, Vol. 43 Issue 1, p73-77. 5p.