Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S M, Bandiera"'
Autor:
E G Hrycay, S M Bandiera
Publikováno v:
Current Drug Metabolism. 10:1151-1183
The present review focuses on the expression, function and regulation of mouse cytochrome P450 (Cyp) enzymes. Information compiled for mouse Cyp enzymes is compared with data collected for human CYP enzymes. To date, approximately 40 pairs of ortholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1a6be100a3d3cf38d7f06cf7fe3bbd
https://doi.org/10.2174/138920009790820138
https://doi.org/10.2174/138920009790820138
Publikováno v:
Biochemical pharmacology. 62(9)
The present study investigated the effect of dietary zinc deficiency during the developmental period on hepatic cytochrome P450 (CYP) expression in postpubertal male rats. Twenty-one-day-old weanling male Wistar rats were randomly assigned to one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0731a5540a6e38b51b971bea5fd1adee
https://pubmed.ncbi.nlm.nih.gov/11705462
https://pubmed.ncbi.nlm.nih.gov/11705462
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(12)
To examine the effect of neonatal administration of tamoxifen on adult expression of hepatic cytochrome P-450 (CYP) enzymes and steroid 5alpha-reductase, male and female Sprague-Dawley rats were injected s.c. with tamoxifen (20 microg) or peanut oil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25f418a47e7b12fa132e49601bab7f23
https://pubmed.ncbi.nlm.nih.gov/10570019
https://pubmed.ncbi.nlm.nih.gov/10570019
Autor:
W, Tang, R A, Stearns, S M, Bandiera, Y, Zhang, C, Raab, M P, Braun, D C, Dean, J, Pang, K H, Leung, G A, Doss, J R, Strauss, G Y, Kwei, T H, Rushmore, S H, Chiu, T A, Baillie
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(3)
The nonsteroidal anti-inflammatory drug diclofenac causes a rare but potentially fatal hepatotoxicity that may be associated with the formation of reactive metabolites. In this study, three glutathione (GSH) adducts, namely 5-hydroxy-4-(glutathion-S-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b96ad3ee02ebc70a64ca18b2eab52cae
https://pubmed.ncbi.nlm.nih.gov/10064567
https://pubmed.ncbi.nlm.nih.gov/10064567
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(10)
This biochemical and pharmacokinetic investigation was undertaken to evaluate the effects of androgen administration during puberty on sex-dependent cytochrome P450 (CYP or P450) enzyme expression in adult female rats. Hepatic testosterone 2alpha-hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24761acef8d6bece1f1465de4c0c90d2
https://pubmed.ncbi.nlm.nih.gov/9763410
https://pubmed.ncbi.nlm.nih.gov/9763410
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(2)
We previously reported that in vivo cimetidine inhibits hepatic microsomal enzyme activities mediated by cytochrome P450 (CYP)2C11 and at least one other CYP enzyme but does not inhibit CYP2A1-, CYP2B- or CYP3A-mediated activities in adult male rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0087f9fa2649ee491e85102b08243701
https://pubmed.ncbi.nlm.nih.gov/9454789
https://pubmed.ncbi.nlm.nih.gov/9454789
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(8)
The purpose of this study was to investigate the impact of prepubertal ovariectomy and postpubertal administration of testosterone on inducibility of rat hepatic CYP2B1 and CYP2B2 by phenobarbital. Intact adult male and female Sprague-Dawley rats wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59dbc9d55bce344db48bea9276d75e2e
https://pubmed.ncbi.nlm.nih.gov/9280408
https://pubmed.ncbi.nlm.nih.gov/9280408
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 260(3)
Cimetidine is considered to be a general inhibitor of cytochrome P-450 enzymes, but there is indirect evidence that certain cytochrome P-450 enzymes are not inhibited by cimetidine. The purpose of this study was to determine whether cimetidine, when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96887db763f8a1743a6bb3028d308f84
https://pubmed.ncbi.nlm.nih.gov/1545403
https://pubmed.ncbi.nlm.nih.gov/1545403
Autor:
L. E. Hart, K. M. Cheng, P. E. Whitehead, R. M. Shah, R. J. Lewis, S. R. Ruschkowski, R. W. Blair, D. C. Bennett, S. M. Bandiera, R. J. Norstrom, G. D. Bellward
Publikováno v:
Journal of toxicology and environmental health. 32(3)
A great blue heron colony located near a pulp mill in British Columbia failed to fledge young in 1987, with a concurrent sharp increase in polychlorinated dibenzo-p-dioxin (PCDD) and polychlorinated dibenzofuran (PCDF) levels in their eggs. In 1988 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37a4858fbec8b7ff0c3705ee9623304
https://pubmed.ncbi.nlm.nih.gov/2002515
https://pubmed.ncbi.nlm.nih.gov/2002515
Autor:
G. D. Bellward, R. J. Norstrom, P. E. Whitehead, J. E. Elliott, S. M. Bandiera, C. Dworschak, T. Chang, S. Forbes, B. Cadario, L. E. Hart, K. M. Cheng
Publikováno v:
Journal of toxicology and environmental health. 30(1)
As part of the Canadian Wildlife Service monitoring of great blue herons in British Columbia, eggs were collected from three colonies with low, intermediate, and high levels of PCDD and PCDF contamination: Nicomekl, Vancouver, and Crofton, respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cccf63542a36820e8d0d672bae7ec6
https://pubmed.ncbi.nlm.nih.gov/2348479
https://pubmed.ncbi.nlm.nih.gov/2348479