Zobrazeno 1 - 10
of 58
pro vyhledávání: '"S Labaume"'
Autor:
Bertrand Arnulf, S. Labaume, Jean-Paul Fermand, Yurdagul Uzunhan, Marie-Olivia Chandesris, L. Repellini, A. Crinquette, Bouchra Asli, Jean Soulier, Claire Fieschi, Karine Chemin, Marion Malphettes, Jean-Christophe Bories
Publikováno v:
British Journal of Haematology. 136:609-614
The t(4;14)(p16;q32) translocation, found in 15% of multiple myeloma (MM) cases, indicates a poor prognosis. Plasma cells (PC) with t(4;14) ectopically express the fibroblast growth factor receptor 3 (FGFR3) tyrosine kinase receptor, which has potent
Publikováno v:
Blood. 83:2206-2210
We previously showed that clonal blood B cells from patients with macroglobulinemia spontaneously differentiate in vitro to plasma cells. This process is dependent on an interleukin (IL)-6 autocrine pathway. We investigate here whether all-trans-reti
Autor:
P, Rousselot, S, Labaume, J P, Marolleau, J, Larghero, M H, Noguera, J C, Brouet, J P, Fermand
Publikováno v:
Cancer research. 59(5)
Recent data have renewed the interest for arsenic-containing compounds as anticancer agents. In particular, arsenic trioxide (As2O3) has been demonstrated to be an effective drug in the treatment of acute promyelocytic leukemia by inducing programmed
Publikováno v:
Leukemialymphoma. 30(3-4)
The effects of all trans retinoic acid (ATRA) on human myeloma cells growth were studied in vitro and in vivo using immunodeficient mice engrafted with malignant plasma cells. ATRA inhibited the in vitro proliferation of plasma cells originating from
Publikováno v:
Clinical and experimental immunology. 104(1)
SUMMARY We previously showed that IL-6 is an autocrine growth factor for two human myeloma cell lines, RPMI 8226 and U266. We investigated here the in vitro and in vivo effects of all-trans retinoic acid (RA) on the growth and survival of these two c
Publikováno v:
Clinical Lymphoma and Myeloma. 9:S138
Autor:
S. Labaume, J. L. Preud'homme
Publikováno v:
Annals of the New York Academy of Sciences. 254:254-261
Publikováno v:
Blood. 56:1136-1140
In a patient with plasma cell leukemia and a kappa type Bence Jones protein in serum and urine, the immunofluorescence study of blood plasma cells showed intracellular gamma and kappa chain determinants. Biosynthesis experiments showed the production
Publikováno v:
Seminars in hematology. 21(4)
Publikováno v:
Leukemia research. 5(4-5)
Philadelphia chromosome and surface IgM were studied at the individual cell level in blood lymphocytes from 18 patients with chronic myelocytic leukemia using an assay that combines surface immunofluorescence and Q-banding. After stimulation by polyc