Zobrazeno 1 - 10
of 31
pro vyhledávání: '"S L Wagner"'
Publikováno v:
Journal of Biological Chemistry. 270:22827-22830
The Alzheimer's disease related protein, amyloid beta-protein precursor (A beta PP), contains a domain homologous to Kunitz-type serine protease inhibitors (KPI). The recombinant KPI domain of A beta PP is a potent inhibitor of coagulation factors XI
Publikováno v:
Journal of Biological Chemistry. 269:30966-30973
The 4-kDa beta-amyloid peptide (A beta), a major constituent of parenchymal amyloid deposits in Alzheimer's disease, is derived from larger amyloid precursor proteins (APP). We have examined the metabolism of APP in Madin-Darby canine kidney cells st
Autor:
S L Wagner, Brian J. Cummings, W E Van Nostrand, Carl W. Cotman, Dennis D. Cunningham, Joseph H. Su, James W. Geddes
Publikováno v:
Neuroscience. 48:763-777
Using a monoclonal antibody raised against purified, native, human protease nexin-2/amyloid precursor protein, which recognizes an amino terminal epitope on the amyloid precursor protein and detects all major isoforms of amyloid precursor protein, we
Publikováno v:
Journal of Biological Chemistry. 265:9591-9594
Protease nexin-2 (PN-2) is a protease inhibitor that is synthesized and secreted by a variety of extravascular cells including human fibroblasts. It forms sodium dodecyl sulfate-stable complexes with trypsin, the epidermal growth factor binding prote
Publikováno v:
Neuron. 43(5)
The amyloid hypothesis of Alzheimer's disease (AD) maintains that the accumulation of the amyloid beta protein (Abeta) is a critical event in disease pathogenesis. A great deal of both academic and commercial research has focused on the mechanisms by
Publikováno v:
The heart surgery forum. 4(1)
Our purpose was to determine if complete revascularization could be successfully performed off bypass in the majority of coronary artery bypass graft (CABG) patients.Using a metabolic protocol and the Medtronic Octopus stabilizer device (Medtronic, I
Autor:
E R, Peskind, J, Leverenz, M R, Farlow, R K, Ito, S A, Provow, R S, Siegel, M, Cleveland, C H, Morgan, M R, Pandian, S, Corbin, D, Nochlin, G D, Schellenberg, M A, Raskind, S L, Wagner
Publikováno v:
Alzheimer disease and associated disorders. 11(4)
The authors compared concentrations of soluble beta-amyloid protein precursor (s beta PP) in cerebrospinal fluid (CSF) in 45 patients diagnosed with probable Alzheimer disease (AD) and 26 normal older control volunteers. Soluble beta-amyloid protein
Autor:
S L, Wagner
Publikováno v:
Occupational medicine (Philadelphia, Pa.). 12(2)
Organophosphate and carbamate insecticides are the most common forms of pesticide poisoning. They present with a distinctive clinical syndrome that is, nevertheless, sometimes difficult to recognize. Early treatment is important, and specific antidot
Autor:
S L, Wagner
Publikováno v:
Journal of AOAC International. 78(1)
Publikováno v:
The Journal of biological chemistry. 269(49)
The 4-kDa beta-amyloid peptide (A beta), a major constituent of parenchymal amyloid deposits in Alzheimer's disease, is derived from larger amyloid precursor proteins (APP). We have examined the metabolism of APP in Madin-Darby canine kidney cells st