Zobrazeno 1 - 10
of 17
pro vyhledávání: '"S L Giardina"'
Autor:
John C. Roder, T. Bino, Stephen K. Anderson, David M. Segal, S. L. Giardina, R. R. S. Kantor, John R. Ortaldo, J. L. Frey
Publikováno v:
The Journal of Experimental Medicine
In an attempt to identify a molecule in target recognition by CD3- large granular lymphocytes (LGL), we have generated a rabbit antiidiotypic (anti-ID) serum against a monoclonal antibody (mAb 36) that reacted with the cell membrane of K562. Flow cyt
Publikováno v:
The Journal of Immunology. 145:1719-1726
This study was designed to examine the expression and function of IL-2R on murine macrophages. We used a model system of murine macrophage cell lines (ANA-1 and GG2EE) that was established by infecting normal murine bone marrow-derived cells with the
Publikováno v:
Blood. 87(6)
The role of a 150-kD SR-cyclophilin (NK-TR1) in monocyte differentiation was investigated. Using an antipeptide monoclonal antibody, we have detected NK-TR1 in human peripheral blood monocytes and HL-60 cells. Unstimulated monocytes showed a low intr
Autor:
S L, Giardina, S K, Anderson, T J, Sayers, W H, Chambers, G A, Palumbo, H A, Young, J R, Ortaldo
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(1)
We have shown that NK-TR1, a protein containing a cyclophilin-like domain, is associated with a receptor/triggering molecule on the surface of human large granular lymphocytes (1). In the present study, we have further defined the role of NK-TR1 in t
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(6)
This study was designed to examine the expression and function of IL-2R on murine macrophages. We used a model system of murine macrophage cell lines (ANA-1 and GG2EE) that was established by infecting normal murine bone marrow-derived cells with the
Autor:
S L Giardina, N Pritikin, David W. Golde, RK Oldham, J Sklar, Kenneth A. Foon, Robert W. Schroff, ML Cleary, CS Woodhouse
Publikováno v:
Blood. 66:1017-1021
Immunoglobulin gene rearrangement analysis and somatic cell hybridization techniques were used to examine the malignant cell population in an unusual patient with hairy cell leukemia and macroglobulinemia (N Engl J Med 296:92, 1977). Although previou
Publikováno v:
The Journal of Immunology. 140:4403-4412
Rat mAb have been raised to mouse liver-derived large granular lymphocytes (LGL). One of these mAb (4D11) binds specifically to mouse LGL and appears to recognize a non-allelic determinant on NK-active cell populations. The Ag recognized by 4D11 is e
Autor:
S L Giardina, R W Schroff, T J Kipps, C S Woodhouse, P G Abrams, H C Rager, A C Morgan, K A Foon
Publikováno v:
The Journal of Immunology. 135:653-658
We developed murine anti-idiotype monoclonal antibodies for each of four patients with B cell-derived leukemias and lymphomas. Idiotypic immunoglobulin was isolated from mouse X human tumor-cell hybridomas or from patients' serum and was used to immu
Publikováno v:
The Journal of Immunology. 140:3528-3533
A murine mAb, STEGI 1, was generated against a 30-kDa raf protein purified from an Escherichia coli expression vector. Immunoblot analysis confirmed that this antibody recognized the original immunizing protein as well as a 44- to 48-kDa protein from
Publikováno v:
The Journal of Immunology. 132:1611-1613
Human-murine hybridomas, generated by fusion of human CLL cells with non-Ig-secreting murine myeloma NS-1, and secreting the IgM kappa expressed on the CLL cell surface, were grown in the peritoneal cavity of doubly pristane-primed nude mice to produ