Zobrazeno 1 - 10
of 25
pro vyhledávání: '"S L Adamson"'
Publikováno v:
Developmental Dynamics. 239:1888-1900
Missense mutations in the Fibroblast Growth Factor Receptor 2 (FGFR2) have been identified in human craniosynostotic syndromes such as Crouzon (CS) and Pfeiffer (PS). FGFR2 has two major isoforms, IIIb and IIIc, generated through alternative splicing
Developmental changes in respiratory, febrile, and cardiovascular responses to PGE2 in newborn lambs
Autor:
S. L. Adamson, T. C. Tai
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 278:R1460-R1473
PGE2 has centrally mediated respiratory, febrile, and cardiovascular effects that markedly differ between fetal and adult life. We hypothesized that the transition from fetal to adult responses to PGE2 occurs in the newborn period. Thus effects of an
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 75:135-142
L'indomethacine, un inhibiteur de synthese des prostaglandines, transforme la respiration foetale normalement intermittente en une respiration quasi continue. Si l'indomethacine agit dans le cerveau, nous emettons l'hypothese qu'elle stimulerait la r
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 270:H16-H23
Endothelin-1 produced by umbilicoplacental tissues may regulate fetal placental perfusion. To investigate its site of action, we measured segmental resistance in this bed in unanesthetized fetal sheep near term during fetal endothelin-1 infusion. A 1
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 268:H558-H568
Aortic hemodynamics were examined in eight conscious newborn sheep. Flow and pressure in the thoracic aorta and pressure in the distal abdominal aorta were measured under control conditions and during pressure changes caused by bottle feeding or duri
Publikováno v:
Brain Research. 652:28-39
Perinatal changes in plasma prostaglandin E2 (PGE2) act at the level of the fetal brainstem to modulate respiratory activity. In-vitro receptor autoradiography was used to determine whether PGE2 binding sites (putative receptors) are located in brain
Autor:
B. L. Langille, S. L. Adamson
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 263:H824-H832
Upper descending thoracic aortic pressures recorded from near-term fetal sheep resembled those recorded in mature animals, but diastolic thoracic aortic flows were much greater than those reported for adults. Furthermore, the pressure wave was not am
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 259:H1247-H1253
We have examined aortic growth and aortic hemodynamics in lambs in the perinatal period. Morphometry of histological cross sections indicated that abdominal aortic circumference decreased by 31% between 131 days of gestation and 2-3 wk postpartum. In
Publikováno v:
Physiological genomics. 10(2)
A new multifrequency (19-55 MHz) ultrasound biomicroscope with two-dimensional imaging and integrated Doppler ultrasound was evaluated using phantoms and isoflurane-anesthetized mice. Phantoms revealed the biomicroscope's lateral resolution was betwe
Publikováno v:
Pediatric research. 47(3)
We hypothesized that placental resistance was elevated and transfer reduced in cotyledons from intrauterine growth-restricted (IUGR) fetuses. We perfused 10 cotyledons from term, normally grown fetuses, six from preterm, normally grown fetuses with n