Zobrazeno 1 - 10
of 12
pro vyhledávání: '"S L, Walsh"'
Autor:
Warren W. Wakarchuk, James C. Richards, Adèle Martin, S L Walsh, Derek W. Hood, Melissa J. Schur, Elke K. H. Schweda, Andrew D. Cox, Mary E. Deadman, E R Moxon
Publikováno v:
Scopus-Elsevier
A genetic basis for the biosynthetic assembly of the globotetraose containing lipopolysaccharide (LPS) of Haemophilus influenzae strain RM118 (Rd) was determined by structural analysis of LPS derived from mutant strains. We have previously shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b4d5c00a5a9b6e777c599b060a227e
https://doi.org/10.1093/glycob/11.11.957
https://doi.org/10.1093/glycob/11.11.957
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 75:631-633
Hereditary haemochromatosis (HH) is a genetic disorder in which abnormal iron handling leads to excessive iron accumulation in systemic tissues. Magnetic resonance imaging studies suggest excess iron deposition in the basal ganglia of patients with H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabeddc2d801659986873438fb984df5
https://doi.org/10.1136/jnnp.2003.027441
https://doi.org/10.1136/jnnp.2003.027441
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(1)
Preclinical studies have demonstrated that kappa-opioid agonists can attenuate the neurochemical and behavioral effects of cocaine that are related to its reinforcing efficacy, suggesting that kappa-agonists may serve as pharmacotherapies for cocaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba3f6fcba527c1450fb1ac689b6af84f
https://pubmed.ncbi.nlm.nih.gov/11561074
https://pubmed.ncbi.nlm.nih.gov/11561074
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(2)
levo-alpha-Acetylmethadol (LAAM) and methadone are full mu-opioid agonists used to treat opioid dependence. Current labeling indicates that LAAM is less potent than methadone. Clinical studies have not determined the relative potency of these drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe3a8bd0cc5504ed9de70dd17e3a1580
https://pubmed.ncbi.nlm.nih.gov/10215673
https://pubmed.ncbi.nlm.nih.gov/10215673
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(1)
Levo-alpha-acetylmethadol (LAAM) is a long-acting opioid agonist approved for use as a maintenance treatment for opioid dependence. Previous clinical studies report that the onset of the effects of LAAM is slower after parenteral administration than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d4eb1a72af6c3960913b378c788e8a1
https://pubmed.ncbi.nlm.nih.gov/9535996
https://pubmed.ncbi.nlm.nih.gov/9535996
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(2)
Levo-alpha-acetylmethadol (LAAM) currently is approved as an opioid maintenance treatment. This double-blind study was designed to characterize withdrawal suppression and opioid blockade produced by two different LAAM maintenance doses. Outpatient op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4c53871e8e4243e4d4567c489060345
https://pubmed.ncbi.nlm.nih.gov/9580575
https://pubmed.ncbi.nlm.nih.gov/9580575
Autor:
T, Eissenberg, G E, Bigelow, E C, Strain, S L, Walsh, R K, Brooner, M L, Stitzer, R E, Johnson
Publikováno v:
JAMA. 277(24)
To compare the clinical efficacy of different doses of levomethadyl acetate hydrochloride (known as LAAM) in the treatment of opioid dependence.A randomized controlled, double-blind, parallel group, 17-week study.Outpatient facilities at Johns Hopkin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94f32e9b31f7e4c4c6878aef6a19d1c5
https://pubmed.ncbi.nlm.nih.gov/9200635
https://pubmed.ncbi.nlm.nih.gov/9200635
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 279(2)
This study evaluated the effects of i.v. cocaine, hydromorphone and their combination, and assessed the ability of oral naltrexone, an opioid antagonist, to modulate these effects. Volunteers with cocaine and heroin abuse histories (n = 8) participat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::045ab1137f8ccccb6d5b7dd3f6071b4c
https://pubmed.ncbi.nlm.nih.gov/8930154
https://pubmed.ncbi.nlm.nih.gov/8930154
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 278(2)
One purpose of this study was to characterize the acute effects of the partial mu-opioid agonist buprenorphine administered to human subjects undergoing maintenance treatment with ascending doses of morphine. A second purpose was to examine the devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f8e19a746b82915f0b308ddee9073e9
https://pubmed.ncbi.nlm.nih.gov/8768738
https://pubmed.ncbi.nlm.nih.gov/8768738
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(1)
Buprenorphine, a mixed opioid agonist-antagonist, is being investigated as a treatment for opioid dependence. This study compared the acute subjective and physiological effects of sublingual buprenorphine to those of p.o. methadone over a wide range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fce647cd55e928d911d164c260e82a61
https://pubmed.ncbi.nlm.nih.gov/7542336
https://pubmed.ncbi.nlm.nih.gov/7542336