Výsledky vyhledávání - "S L, Streicher"

Characterization of methyltransferase and hydroxylase genes involved in the biosynthesis of the immunosuppressants FK506 and FK520

Autor: Sheng-Jian Cai, Randall R. Miller, Haideh Motamedi, Ali Shafiee, S L Streicher, Byron H. Arison

Publikováno v: Journal of Bacteriology. 178:5243-5248

FK506 and FK520 are 23-membered macrocyclic polyketides with potent immunosuppressive and antifungal activities. The gene encoding 31-O-demethyl-FK506 methyltransferase, fkbM, was isolated from Streptomyces sp. strains MA6858 and MA6548, two FK506 pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbceb5319819ef1bd63adb6a7dc5d26
https://doi.org/10.1128/jb.178.17.5243-5248.1996

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The genetic and biochemical basis of polyketide metabolism in microorganisms and its role in drug discovery and development

Autor: C R, Hutchinson, C W, Borell, M J, Donovan, F, Kato, H, Motamedi, H, Nakayama, R L, Rubin, S L, Streicher, R G, Summers, E, Wendt-Pienkowski

Publikováno v: Planta medica. 57(7)

The possibilities for the design of new drug screening and development strategies directed to a specific objective on the basis of genetic engineering of microorganisms is discussed from two points of view. Firstly, results of work on genetic hybrids

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::14efde18e95a49133300027f889ac527
https://pubmed.ncbi.nlm.nih.gov/1956956

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The genetic and biochemical basis of polyketide metabolism in microorganisms and its role in drug discovery and development

Autor: H. Nakayama, M. J. Donovan, Haideh Motamedi, R. L. Rubin, Richard G. Summers, C R Hutchinson, S. L. Streicher, Evelyn Wendt-Pienkowski, W. L. Wessel, F. Kato, C. W. Borell

Publikováno v: Planta medica. 57

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f976d833c6f6ffcd33a1664b9f3768
https://pubmed.ncbi.nlm.nih.gov/17226221

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Genetic control of glutamine synthetase in Klebiella aerogenes

Autor: Robert A. Bender, Boris Magasanik, S L Streicher

Publikováno v: Journal of Bacteriology. 121:320-331

Mutations at two sites, glnA and glnB, of the Klebsiella aerogenes chromosome result in the loss of glutamine synthetase. The locations of these sites on the chromosome were established by complementation by episomes of Escherichia coli and by determ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a2e5e0610921f56946589be2cc6198
https://doi.org/10.1128/jb.121.1.320-331.1975

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X-ray diagnosis of closed traumatic injuries of the facial skull

Autor: I. I. Kamalov, S. L. Streicher

Publikováno v: Kazan medical journal. 69:111-114

X-ray diagnosis of closed traumatic injuries of the facial skull is a difficult task due to the complexity of its anatomical structure. Improvement of technique and technique of X-ray examination changes the former idea about the nature of facial cra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1eea208d9cf8a74ebd78c8d3e21d1bb4
https://doi.org/10.17816/kazmj97209

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Comparative Biochemistry of Nitrogen Fixation

Autor: S L Streicher, R C Valentine

Publikováno v: Annual Review of Biochemistry. 42:279-302

INTRODUCTION 279 ELECTRON TRANSPORT CHAINS LINKING NITROGENASE ......... 280 ELECTRON DONORS 280 Pyruvate, HI, and formate 281 Pyridine nucleotides 283 Photosynthetic donors 284 ELECTRON CARRIERS 285 Ferredoxins 285 Flavodoxins 289 NITROGENASE 290 AM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1af75d53a7a74e7c37dadf1541c6d2b
https://doi.org/10.1146/annurev.bi.42.070173.001431

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Characterization of suppressible mutations in the viomycin phosphotransferase gene of the Streptomyces enteric plasmid pVE138

Autor: Gary P. Roberts, S L Streicher, R B Goldberg, M J Paradiso

Publikováno v: Journal of Bacteriology. 169:1325-1327

The viomycin phosphotransferase gene (vph) is expressed and confers resistance to viomycin in both Streptomyces spp. and members of the family Enterobacteriaceae. We report the isolation of UGA (opal) and UAG (amber) mutations in the vph gene of shut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a6d09c5b35dff299fbd0d3bad2cde7
https://doi.org/10.1128/jb.169.3.1325-1327.1987

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Glutamine synthetase of Klebsiella aerogenes: properties of glnD mutants lacking uridylyltransferase

Autor: F Foor, S L Streicher, Boris Magasanik, S G Rhee, R J Cedergren

The glnD mutation of Klebsiella aerogenes is cotransducible by phage P1 with pan (requirement for pantothenate) and leads to a loss of uridylytransferase and uridylyl-removing enzyme, components of the glutamine synthetase adenylylation system. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c127e99a5f229140612b0f176feb2c
https://europepmc.org/articles/PMC222287/

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Purification of glutamine synthetase from a variety of bacteria

Autor: S L Streicher, B Tyler

Publikováno v: Journal of bacteriology. 142(1)

We have developed two procedures which allow the very rapid purification of glutamine synthetase (GS) from a diverse variety of bacteria. The first procedure, based upon differential sedimentation, depends upon the association of GS with deoxyribonuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321c4d777483982ddbf886f81381e235
https://pubmed.ncbi.nlm.nih.gov/6102984

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