Zobrazeno 1 - 10
of 13
pro vyhledávání: '"S L, Lahrichi"'
Publikováno v:
Journal of Medicinal Chemistry. 42:3175-3182
In an earlier report we identified specific modifications and substitutions of corticotropin releasing factor (CRF) that led to the discovery of antagonists with extended duration of action as compared to that of astressin {cyclo(30-33)[DPhe(12),Nle(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af07011f8e7067277b16badf38c2cfb
https://doi.org/10.1021/jm9902133
https://doi.org/10.1021/jm9902133
Autor:
J. Gulyas, Anne Z. Corrigan, Jean Rivier, S L Lahrichi, Wylie Vale, A. G. Craig, Steven C. Koerber, Catherine Rivier
Publikováno v:
Journal of Medicinal Chemistry. 41:5002-5011
We hypothesized that covalent constraints such as side-chain to side-chain lactam rings would stabilize an alpha-helical conformation shown to be important for the recognition and binding of the human corticotropin-releasing factor (hCRF) C-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1e9545ba540cca38ace8e9d83f77dd
https://doi.org/10.1021/jm980350k
https://doi.org/10.1021/jm980350k
Autor:
Arnold T. Hagler, John S. Porter, Anne Z. Corrigan, Jean Rivier, Guangcheng Jiang, S L Lahrichi, Lila M. Gierasch, Steven C. Koerber, Catherine Rivier, Josep Rizo, Wylie Vale
Publikováno v:
Human Reproduction. 11:133-147
To whom correspondence should be addressedWhile the clinical significance of gonadotrophin-releasing hormone (GnRH)agonists is well recognized, the potential use of GnRH antagonists in humansawaits the availability of potent analogues with no untowar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c21bddb113256904b5670739071fdb
https://doi.org/10.1093/humrep/11.suppl_3.133
https://doi.org/10.1093/humrep/11.suppl_3.133
Autor:
B. Braun, Jean Rivier, Nicolas Chartrel, Mauro Vallarino, S L Lahrichi, Hubert Vaudry, David Waugh, Francoise Collin, J M Conlon
Publikováno v:
The Journal of Comparative Neurology. 364:324-339
Urotensin II (UII) is traditionally regarded as a product of the neurosecretory cells in the caudal portion of the spinal cord of jawed fishes. A peptide related to UII has been recently isolated from the frog brain, thereby providing the first evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ca5acae3105af4a4a76c89b90e0aa0f
https://doi.org/10.1002/(sici)1096-9861(19960108)364:2<324::aid-cne10>3.0.co
https://doi.org/10.1002/(sici)1096-9861(19960108)364:2<324::aid-cne10>3.0.co
Autor:
Steven C. Koerber, J. Gulyas, Marilyn H. Perrin, Wylie Vale, A Corrigan, A. G. Craig, S L Lahrichi, Jean Rivier, Steven W. Sutton, Catherine Rivier
Publikováno v:
Proceedings of the National Academy of Sciences. 92:10575-10579
Predictive methods, physicochemical measurements, and structure activity relationship studies suggest that corticotropin-releasing factor (CRF; corticoliberin), its family members, and competitive antagonists (resulting from N-terminal deletions) usu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412c992b9b3eabf73664aefa31165868
https://doi.org/10.1073/pnas.92.23.10575
https://doi.org/10.1073/pnas.92.23.10575
Autor:
S. C. Koerber, Antonio Miranda, Wylie Vale, Jean Rivier, S L Lahrichi, A Corrigan, J. Gulyas, Arnold T. Hagler, Catherine Rivier, A. G. Craig
Publikováno v:
Journal of Medicinal Chemistry. 37:1450-1459
Corticotropin releasing factor (CRF) is a 41-peptide amide which stimulates the release of ACTH (Vale et al. Science 1981, 213, 1394). CRF has been postulated to assume an alpha-helical conformation upon binding to its pituitary receptor (Hernandez e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de9ce85d4f95483f5d53e67f4ee046e
https://doi.org/10.1021/jm00036a010
https://doi.org/10.1021/jm00036a010
Autor:
R. Scott Struthers, S L Lahrichi, Laura A. Cervini, Steven C. Koerber, Catherine Rivier, Jean Rivier, Dean A. Kirby, Guangcheng Jiang, Michel Ibea, John S. Porter
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a295a5f80a82d18fc783b20a24f99bed
https://doi.org/10.1002/chin.200022171
https://doi.org/10.1002/chin.200022171
Autor:
Jean Rivier, John S. Porter, Dean A. Kirby, S L Lahrichi, R. Scott Struthers, Laura A. Cervini, Steven C. Koerber, Catherine Rivier
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::789afa720af616db2cde228e740456ce
https://doi.org/10.1002/chin.200022172
https://doi.org/10.1002/chin.200022172
Autor:
Jean Rivier, Anne Z. Corrigan, Antonio Miranda, Charleen Miller, A. G. Craig, Steven C. Koerber, S L Lahrichi, Catherine Rivier, J. Gulyas, Wylie Vale, Steve Sutton
Publikováno v:
American Peptide Symposia ISBN: 0792351606
CRF [1] is involved in a wide spectrum of central nervous system (CNS)-mediated effects, suggesting that this peptide plays an important role within the brain, especially in response to stressful stimuli [2]. Systematic SAR investigations have result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bae35d2fb028b68a99fe89816299109f
https://doi.org/10.1007/0-306-46862-x_321
https://doi.org/10.1007/0-306-46862-x_321
Autor:
N, Chartrel, J M, Conlon, F, Collin, B, Braun, D, Waugh, M, Vallarino, S L, Lahrichi, J E, Rivier, H, Vaudry
Publikováno v:
The Journal of comparative neurology. 364(2)
Urotensin II (UII) is traditionally regarded as a product of the neurosecretory cells in the caudal portion of the spinal cord of jawed fishes. A peptide related to UII has been recently isolated from the frog brain, thereby providing the first evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e740e28f2ca91ec3da90e12a9a6f7bc6
https://pubmed.ncbi.nlm.nih.gov/8788253
https://pubmed.ncbi.nlm.nih.gov/8788253