Zobrazeno 1 - 4
of 4
pro vyhledávání: '"S L, Koprak"'
Publikováno v:
The Journal of Immunology. 144:1418-1424
The structurally related immunosuppressive macrolides FK-506 and rapamycin (RAP) were previously shown to inhibit T cell stimulation through different mechanisms. FK-506 acts similarly to cyclosporin A (CsA) and prevents IL-2 production and IL-2R exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c307bc60c4b83a57803310943b28ffa
https://doi.org/10.4049/jimmunol.144.4.1418
https://doi.org/10.4049/jimmunol.144.4.1418
Publikováno v:
The Journal of Immunology. 144:251-258
FK-506 and the structurally related macrolide rapamycin (RAP) were investigated in comparison with cyclosporin A (CsA) for their immunosuppressive effects on murine T cells. All three agents suppressed the proliferation of splenic T cells triggered b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc047e7efdeabe52480934662bffb750
https://doi.org/10.4049/jimmunol.144.1.251
https://doi.org/10.4049/jimmunol.144.1.251
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(1)
FK-506 and the structurally related macrolide rapamycin (RAP) were investigated in comparison with cyclosporin A (CsA) for their immunosuppressive effects on murine T cells. All three agents suppressed the proliferation of splenic T cells triggered b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4340ae3766c821b2aa5f00f721440fa
https://pubmed.ncbi.nlm.nih.gov/1688572
https://pubmed.ncbi.nlm.nih.gov/1688572
Autor:
P L, Durette, J, Boger, F, Dumont, R, Firestone, R A, Frankshun, S L, Koprak, C S, Lin, M R, Melino, A A, Pessolano, J, Pisano
Publikováno v:
Transplantation proceedings. 20(2 Suppl 2)
In order to establish whether CyP is the pharmacologically relevant CsA receptor, the CyP binding v immunosuppressive activity was measured for an extensive, structurally varied group of CsA analogues. Overall, CyP binding was found to parallel immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b7f46afd071e272afe79e724a494967
https://pubmed.ncbi.nlm.nih.gov/2966482
https://pubmed.ncbi.nlm.nih.gov/2966482