Zobrazeno 1 - 10
of 18
pro vyhledávání: '"S L, Hazen"'
Autor:
T. Bosdet, Zeneng Wang, A. Koochin, J. Branov, G. Horvath, S. L. Hazen, H. D. Vallance, A. Rosen-Heath
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 15, Iss, Pp 130-133 (2018)
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports
Oral supplementation with l-carnitine is a common therapeutic modality for mitochondrial disorders despite limited evidence of efficacy. Recently, a number of studies have demonstrated that a gut microbiota-dependent metabolite of l-carnitine, trimet
Autor:
T. Kawamoto, S. G. Cho, T. Glant, B. Dzhambazov, G. Schwartzman, Takehiko Sato, L. Jiang, R. Mattsson, P. G. Oliveira, T. Chiba, M. Zafarullah, I. Chinen, M. Bokarewa, M. Sakuramoto, B. Yadav, Y. Yu, M. Sugihara, Y. Ishida, J. Tong, H. Idborg, S. Best, A. Hellvard, K. M. Hamel, Y. Yoshikai, J. Ryu, M. Kuhne, G. Fernahl, Yoshi Okamoto, K. Matsumoto, T. Yamamura, H. Park, A. Akitsu, H. Akiyama, M. Kawano, T. Baba, Y. Wang, M. J. Park, K. S. Park, A. Morinobu, X. Fan, E. Jang, J. Smolen, H. Dun, Y. Takasaki, Q. Shao, M. Oyama, J. J. Inglis, M. Yanagida, F. Makino, Q. Wei, D. Kamimura, Z. Wang, Y. Shi, S. Im, Y. Miyamoto, M. Yoshioka, T. Warita, G. Schabbauer, T. Hirano, K. Takatsu, H. Ishigame, L. Morawietz, A. Ma, M. Itakura, S. Cuzzocrea, H. Akiba, H. Kurata, B. Niederreiter, W. Kuon, M. Attar, Y. Usui, Seiji Kanazawa, M. Inui, Ranjeny Thomas, D. Klaczkowska, Y. Hu, K. Tokoyda, T. Nakahama, J. Kim, R. Arakaki, T. Okamoto, B. Ma, T. Izawa, H. Liang, P. Mydel, M. Ruutu, K. Nakano, Y. Tanaka, K. Hanami, K. E. McNamee, A. Oyamada, E. J. Jeon, C. Rintisch, S. L. Hazen, Y. Arima, S. Y. Min, C. D. Surh, Y. Miyazaki, S. Asano, L. Spahiu, M. Brisslert, Y. O. Jung, S. Blüml, E. H. Weiss, A. Pizzolla, J. Saegusa, C. Ra, K. Saito, S. Wang, J. Ma, J. Sieper, S. Yu, C. Ohlsson, Y. Okuyama, W. Lee, Q. Li, J. Y. Lym, X. Wang, P. Anand, X. Yang, D. Ichikawa, L. Bäckdahl, M. Kadowaki, R. Rodeghero, M. Ikeda, T. Kataoka, J. Y. Jhun, J. Tian, S. Li, M. Erlandsson, A. Pitsillides, F. E. McCann, M. Vestberg, B. Y. Yoon, A. Chiba, K. Gustafsson, A. Mirshafiey, T. Sugoh, M. Yamagishi, J. Taguchi, B. Cong, P. Daloze, H. Nagase, P. Leclerc, Y. Hayashi, T. Kishimoto, D. Goto, W. Cho, G. Bou-Gharios, N. Nguyen, S. A. Alzabin, K. Okumura, T. Nakayama, R. M. Xavier, R. O. Williams, H. Ogura, L. Dahlberg, K. Hagenow, M. Kanamoto, B. Shan, P. Stenberg, M. Seipel, L. Song, Y. Cao, T. Masuzawa, Z. Su, H. Xu, Y. Okayama, C. A. Lowell, J. Chen, Saparna Pai, I. Matsumoto, K. Masuda, M. L. Cho, Y. Yoshiga, K. Mikecz, K. Wing, S. Tanaka, P. A. Vo, P. Strzyz, R. Katori, R. Tajima, S. Morimoto, S. Kim, A. Kimura, H. Tagita, C. Larsson, K. Gelderman, S. Ito, P. D. Doodes, K. Misaki, T. Sumida, T. Fukui, H. Y. Kim, K. Yamaoka, W. Zhao, H. Fujii, J. Jiang, J. Van Ziffle, T. G. Batsalova, S. Kumagai, S. Y. Lee, J. Ito, S. Koyasu, R. Holmdahl, M. K. Park, P. Jakobsson, H. Chen, J. S. Park, H. J. Oh, L. Bian, U. Norin, J. G. Ryu, J. Tuncel, F. Saadat, J. Youn, K. Redlich, L. Lu, N. Ishimaru, S. Miyake, M. Horikoshi, S. Liu, Y. Iwakura, R. Di Paola, M. Bonelli, A. Finnegan, H. Shimada, T. Kondo, M. Kimura, M. Korotkova, M. Hultqvist, K. Miyashita, Y. Abe, M. Tanaka, T. Negoro, J. Im, P. Scapini, S. Segawa, M. Murakami, S. Kasagi, A. Savitskaya, H. Yamada, R. Oura, S. Nunomura, R. Roesler, K. A. Gelderman, N. Mukaida, H. S. Park, S. Pawelzik, A. Jash, E. Tanaka, T. Tsujimura, S. Saijo, P. Wu, K. Hashimoto, H. Uga, M. Gregorian, T. Okazawa, T. Hayashi, W. Wang, F. Cunha, H. Inoko, S. Kakuta, Y. Matsuzaka, E. R. Elliott, S. Nagai, Y. Nakano
Publikováno v:
International Immunology.
Autor:
S. L. Hazen, M.-L. Brennan
Publikováno v:
Amino acids. 25(3-4)
Substantial evidence suggests that oxidative events contribute to the pathogenesis of atherosclerotic heart disease. For example, animal model data and numerous in vitro studies point to specific pathways as participants in disease initiation and pro
Autor:
M, Arlandson, T, Decker, V A, Roongta, L, Bonilla, K H, Mayo, J C, MacPherson, S L, Hazen, A, Slungaard
Publikováno v:
The Journal of biological chemistry. 276(1)
Although the pseudohalide thiocyanate (SCN(-)) is the preferred substrate for eosinophil peroxidase (EPO) in fluids of physiologic halide composition, the product(s) of this reaction have not been directly identified, and mechanisms underlying their
Publikováno v:
The Journal of biological chemistry. 274(37)
Publikováno v:
The Journal of biological chemistry. 274(36)
Eosinophil peroxidase (EPO) has been implicated in promoting oxidative tissue injury in conditions ranging from asthma and other allergic inflammatory disorders to cancer and parasitic/helminthic infections. Studies thus far on this unique peroxidase
Autor:
J W, Heinecke, F F, Hsu, J R, Crowley, S L, Hazen, C, Leeuwenburgh, D M, Mueller, J E, Rasmussen, J, Turk
Publikováno v:
Methods in enzymology. 300
Publikováno v:
Methods in enzymology. 300
Publikováno v:
The Journal of biological chemistry. 273(9)
We have recently demonstrated that neutrophils oxidize nearly all of the amino acids commonly found in plasma to a corresponding family of aldehydes in high yield. The reaction is mediated by hypochlorous acid (HOCl), the major oxidant generated by t
Publikováno v:
Free radical biologymedicine. 23(6)
Oxidative modification of proteins has been implicated in a variety of processes ranging from atherosclerosis to aging. Identifying the underlying oxidation pathways has proven difficult, however, due to the lack of specific markers for distinct oxid