Zobrazeno 1 - 8
of 8
pro vyhledávání: '"S L, DeMeester"'
Autor:
Yuyu Qiu, S. L. Demeester, J. P. Cobb, Timothy G. Buchman, Irene E. Karl, Richard S. Hotchkiss, K. Dunnigan
Publikováno v:
Critical Care Medicine. 26:1500-1509
OBJECTIVES To determine a mechanism by which nitric oxide alters induction of stress-induced endothelial cell apoptosis in vitro. Apoptosis is a form of cellular suicide that has been implicated in the pathogenesis of multiple organ dysfunction syndr
Autor:
Kevin W. Tinsley, Timothy G. Buchman, Irene E. Karl, Dale F. Osborne, S. L. Demeester, Richard S. Hotchkiss, J. Perren Cobb
Publikováno v:
Surgery. 124:362-371
Background: Apoptosis, a mechanism of cell death prominent in critical illnesses including disseminated inflammation and multiorgan dysfunction syndrome, is characterized by morphologic changes including cell shrinkage, condensation of organelles, bl
Autor:
J. P. Cobb, S. L. Demeester, K. Dunnigan, Timothy G. Buchman, Irene E. Karl, Richard S. Hotchkiss, Yuyu Qiu
Publikováno v:
Shock. 10:1-6
Transcription factor NF-kappaB is an important regulator of the cellular response to diverse stresses. Pyrrolidine dithiocarbamate (PDTC), an inhibitor of NF-kappaB activity, was used to determine the role of this transcription factor in our model of
Autor:
Ammini K. Jacob, Paul E. Swanson, Masako Hiramatsu, S. L. Demeester, J. Perren Cobb, Timothy G. Buchman, Irene E. Karl, Richard S. Hotchkiss
Publikováno v:
Surgery. 122:243-254
Background. Iron participates in diverse pathologic processes by way of the Fenton reaction, which catalyzes the formation of reactive oxygen species (ROS). To test the hypothesis that this reaction accelerates apoptosis, we used human umbilical vein
Autor:
S L, DeMeester, J P, Cobb, R S, Hotchkiss, D F, Osborne, I E, Karl, K W, Tinsley, T G, Buchman
Publikováno v:
Surgery. 124(2)
Apoptosis, a mechanism of cell death prominent in critical illnesses including disseminated inflammation and multiorgan dysfunction syndrome, is characterized by morphologic changes including cell shrinkage, condensation of organelles, blebbing, and
Autor:
S. L. Demeester, Ammini K. Jacob, J. Perren Cobb, Keith Dunnigan, Richard S. Hotchkiss, Yuyu Qiu, Timothy G. Buchman, Irene E. Karl
Publikováno v:
Archives of Surgery. 132:1283
Objective: To determine whether prior heat shock would attenuate endothelial cell apoptosis and whether any effect of preemptive heat shock is mediated through a nuclear factor kappa B and inhibitor kappa B α mechanism. Design: A randomized, control
Publikováno v:
Shock. 7:117
Publikováno v:
Shock. 5:72