Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S L, Carrithers"'
Autor:
Michael T. Barber, Scott A. Waldman, Scott D. Goldstein, Sanjoy Biswas, P. K. Park, S. L. Carrithers, Scott J. Parkinson
Publikováno v:
Proceedings of the National Academy of Sciences. 93:14827-14832
Guanylyl cyclase C (GCC) has been detected only in intestinal mucosa and colon carcinoma cells of placental mammals. However, this receptor has been identified in several tissues in marsupials, and its expression has been suggested in tissues other t
Autor:
Allan M. Lefer, Patricia M. Pooler, Sean V. Ryan, Carsten Skurk, Scott A. Waldman, Charles Nuss, S. L. Carrithers, Charles S. Owen, Scott J. Parkinson
Publikováno v:
The Journal of Clinical Pharmacology. 36:365-373
Amifostine, a chemo- and radioprotective agent developed as adjunctive therapy for malignancies, induces hypotension after approximately 20% of patient administrations. This study examines the molecular mechanisms underlying hypotension induced by am
Autor:
Scott A. Waldman, Scott D. Goldstein, Raymond W. Urbanski, S. L. Carrithers, Scott J. Parkinson, Pauline K. Park
Publikováno v:
Diseases of the Colon & Rectum. 39:171-181
PURPOSE: Receptors forEscherichia coliheat-stable toxin (ST) are selectively expressed in membranes of intestinal mucosa cells and colon carcinoma cellsin vitro,suggesting their use as a marker for colorectal tumorsin vivo.The present studies examine
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1245:29-36
Internalization of Escherichia coli heat-stable enterotoxin (ST) mediated by guanylyl cyclase C was examined in T84 human colon carcinoma cells. Surface-associated, receptor-bound ST was quantitatively separated from intracellular ligand employing ac
Autor:
Pauline Park, Scott J. Parkinson, Scott M. Goldstein, Donald C. Robertson, S. L. Carrithers, Scott A. Waldman
Publikováno v:
Gastroenterology. 107:1653-1661
Background/Aims: Escherichia coli heat-stable enterotoxins (ST) are small peptides of 18 or 19 amino acids that bind to specific cell surface receptors located on the intestinal brush border and activate guanylate cyclase, resulting in an increase in
Publikováno v:
Journal of Biological Chemistry. 269:22683-22690
Opposing adenine nucleotide-dependent pathways regulating guanylyl cyclase C (GC-C) in rat intestinal membranes have been identified and characterized. ATP analogues substituted in the 2-position were potent inhibitors of basal and Escherichia coli h
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(10)
Formyl peptide receptor activation of three mitogen-activated protein kinase (MAPK) cascades, extracellular signal-regulated kinases (ERKs), N-terminal kinases (JNKs), and p38 MAPK was examined in differentiated HL-60 granulocytes. FMLP stimulated a
Publikováno v:
The Journal of biological chemistry. 269(36)
Opposing adenine nucleotide-dependent pathways regulating guanylyl cyclase C (GC-C) in rat intestinal membranes have been identified and characterized. ATP analogues substituted in the 2-position were potent inhibitors of basal and Escherichia coli h
Autor:
Jerald L. Hoffman, S. L. Carrithers
Publikováno v:
Biochemical pharmacology. 48(5)
Thioether methyltransferase (S-adenosyl-l-methionine: thioether S-methyltransferase; EC 2.1.1.96) catalyzes the methylation of X in compound of the type R-X-R′(X = S, Se, Te), yielding a methyl onium ion. Previous results using mice have demonstrat
Autor:
R. Urbanski, Scott A. Waldman, P. K. Park, S. L. Carrithers, Scott J. Parkinson, Scott M. Goldstein
Publikováno v:
Clinical Pharmacology & Therapeutics. 59:187-187