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Akademický článek

Multi-Residue Analysis of Thyreostats in Animal Muscle Tissues by Hydrophilic Interaction Liquid Chromatography Tandem Mass Spectrometry: A Thorough Chromatographic Study

Autor: Anastasia S. Kritikou, Marilena E. Dasenaki, Niki C. Maragou, Marios G. Kostakis, Nikolaos S. Thomaidis

Publikováno v: Separations, Vol 11, Iss 9, p 269 (2024)

Τhyreostats (TSs) are veterinary drugs used in livestock farming for fattening. Their administration is banned in the European Union since 1981, and their monitoring for food quality and safety control requires sensitive and confirmatory methods. Th

Externí odkaz: https://doaj.org/article/643e8b0804244b089c6562b2a17b21ac

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Akademický článek

Ultrasound-Assisted Extraction of Total Phenolic Compounds and Antioxidant Activity Evaluation from Oregano (Origanum vulgare ssp. hirtum) Using Response Surface Methodology and Identification of Specific Phenolic Compounds with HPLC-PDA and Q-TOF-MS/MS

Autor: Afroditi Michalaki, Haralabos C. Karantonis, Anastasia S. Kritikou, Nikolaos S. Thomaidis, Marilena E. Dasenaki

Publikováno v: Molecules, Vol 28, Iss 5, p 2033 (2023)

Oregano is native to the Mediterranean region and it has been reported to contain several phenolic compounds particularly flavonoids that have been related with multiple bioactivities towards certain diseases. Oregano is cultivated in the island of L

Externí odkaz: https://doaj.org/article/330f3a237aec414a8d6096bfbf14788f

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Akademický článek

Ultrasound-Assisted Extraction of Specific Phenolic Compounds from Petroselinum crispum Leaves Using Response Surface Methodology and HPLC-PDA and Q-TOF-MS/MS Identification

Autor: Afroditi Michalaki, Haralabos C. Karantonis, Anastasia S. Kritikou, Nikolaos S. Thomaidis, Marilena E. Dasenaki

Publikováno v: Applied Sciences, Vol 13, Iss 2, p 798 (2023)

Petroselinum crispum is native to the Mediterranean region and has been reported to contain several phenolic compounds in addition to the highest quantity of apigenin among several natural raw materials. The aim of the present study was to establish

Externí odkaz: https://doaj.org/article/fe75cbcabb55417d9c88dab1c3b6f4e9

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Akademický článek

The 'Crosstalk' between Microbiota and Metabolomic Profile of Kefalograviera Cheese after the Innovative Feeding Strategy of Dairy Sheep by Omega-3 Fatty Acids

Autor: Athina Tzora, Aikaterini Nelli, Anastasia S. Kritikou, Danai Katsarou, Ilias Giannenas, Ilias Lagkouvardos, Nikolaos S. Thomaidis, Ioannis Skoufos

Publikováno v: Foods, Vol 11, Iss 20, p 3164 (2022)

The purpose of this study was to examine the effects of two different feeding systems, a control or a flaxseed and lupin diet (experimental), for a sheep flock, on the microbiota and metabolome of Kefalograviera cheese samples produced by their milk.

Externí odkaz: https://doaj.org/article/5ca965374b1d4f17a336393ee663383e

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Akademický článek

β-Glucosidase and β-Galactosidase-Mediated Transglycosylation of Steviol Glycosides Utilizing Industrial Byproducts

Autor: Anastasia Zerva, Koar Chorozian, Anastasia S. Kritikou, Nikolaos S. Thomaidis, Evangelos Topakas

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)

Stevia rebaudiana Bertoni is a plant cultivated worldwide due to its use as a sweetener. The sweet taste of stevia is attributed to its numerous steviol glycosides, however, their use is still limited, due to their bitter aftertaste. The transglycosy

Externí odkaz: https://doaj.org/article/29d255f7455346daaff41257fb216383

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Akademický článek

Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells

Autor: Joanna S. Kritikou, Mariana M.S. Oliveira, Julien Record, Mezida B. Saeed, Saket M. Nigam, Minghui He, Marton Keszei, Arnika K. Wagner, Hanna Brauner, Anton Sendel, Saikiran K. Sedimbi, Stamatina Rentouli, David P. Lane, Scott B. Snapper, Klas Kärre, Peter Vandenberghe, Jordan S. Orange, Lisa S. Westerberg

Publikováno v: JCI Insight, Vol 6, Iss 6 (2021)

X-linked neutropenia (XLN) is caused by gain-of-function mutations in the actin regulator Wiskott-Aldrich Syndrome protein (WASp). XLN patients have reduced numbers of cytotoxic cells in peripheral blood; however, their capacity to kill tumor cells r

Externí odkaz: https://doaj.org/article/c629a13a387342b6b4e5b5c45a493ae0

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Akademický článek

An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma

Publikováno v: Haematologica, Vol 105, Iss 5 (2020)

Megakaryoblastic leukemia 1 (MKL1) is a coactivator of serum response factor and together they regulate transcription of actin cytoskeleton genes. MKL1 is associated with hematologic malignancies and immunodeficiency, but its role in B cells is unexp

Externí odkaz: https://doaj.org/article/d0de30ab92fb41d9b2253b0c0a309db4

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Akademický článek

Nuclear Wiskott–Aldrich syndrome protein co-regulates T cell factor 1-mediated transcription in T cells

Autor: Nikolai V. Kuznetsov, Bader Almuzzaini, Joanna S. Kritikou, Marisa A. P. Baptista, Mariana M. S. Oliveira, Marton Keszei, Scott B. Snapper, Piergiorgio Percipalle, Lisa S. Westerberg

Publikováno v: Genome Medicine, Vol 9, Iss 1, Pp 1-18 (2017)

Abstract Background The Wiskott–Aldrich syndrome protein (WASp) family of actin-nucleating factors are present in the cytoplasm and in the nucleus. The role of nuclear WASp for T cell development remains incompletely defined. Methods We performed W

Externí odkaz: https://doaj.org/article/0361830f057d4d0aa6483dff822ab402

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