Inoculation route-dependent Lassa virus dissemination and shedding dynamics in the natural reservoir – Mastomys natalensis

Autor: D. M. Wozniak, S. A. Riesle-Sbarbaro, N. Kirchoff, K. Hansen-Kant, A. Wahlbrink, A. Stern, A. Lander, K. Hartmann, S. Krasemann, A. Kurth, J. Prescott

Publikováno v: Emerging Microbes and Infections, Vol 10, Iss 1, Pp 2313-2325 (2021)

Lassa virus (LASV), a Risk Group-4 zoonotic haemorrhagic fever virus, affects sub-Saharan African countries. Lassa fever, caused by LASV, results in thousands of annual deaths. Although decades have elapsed since the identification of the Natal multi

Externí odkaz: https://doaj.org/article/0ff16b2e47e54e118abc44d583c49197

The neuroprotective function of exosomal-PrP C in Alzheimer's disease

Autor: Hartmann, Alexander, C Muth, S Krasemann, D Svergun, S Da Vela, C Betzel, M Glatzel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd3954d005c2053ff5d585ef4cffa029

Mpox outbreak-tecovirimat resistance, management approaches, and challenges in HIV-endemic regions.

Autor: Bapolisi WA; Center for Tropical Diseases and Global Health, Faculty of Medicine, Catholic University of Bukavu, 02 Bukavu, Democratic Republic of the Congo., Krasemann S; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Wayengera M; Department of Immunisable diseases, Uganda Virus Research Institute, Kampala, Uganda., Kirenga B; Department of Research and Innovation, Makerere University Lung Institute, Kampala, Uganda; Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda., Bahizire E; Center for Tropical Diseases and Global Health, Faculty of Medicine, Catholic University of Bukavu, 02 Bukavu, Democratic Republic of the Congo; Department of Nutrition and Health, Centre de Recherche en Sciences Naturelles de Lwiro, Bukavu, Democratic Republic of the Congo., Malembaka EB; Center for Tropical Diseases and Global Health, Faculty of Medicine, Catholic University of Bukavu, 02 Bukavu, Democratic Republic of the Congo; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Heath, Baltimore, MD, USA., Siewe Fodjo JN; Global Health Institute, University of Antwerp, Antwerp, Belgium., Colebunders R; Global Health Institute, University of Antwerp, Antwerp, Belgium; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK., Katoto PD; Center for Tropical Diseases and Global Health, Faculty of Medicine, Catholic University of Bukavu, 02 Bukavu, Democratic Republic of the Congo; Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa; Cochrane South Africa, South African Medical Research Council, Cape Town, South Africa. Electronic address: katoto.chimusa@ucbukavu.ac.cd.

Publikováno v: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Nov; Vol. 24 (11), pp. e672-e673. Date of Electronic Publication: 2024 Sep 10.

Severe mpox in an immunocompromised patient complicated by deep tissue infection: A case report.

Autor: Pfefferle S; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Schweizer M; Morphology and Electron Microscopy Core Facility, Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany., Hartmann K; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.; Core Facility for (Mouse) Pathology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Berger J; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Nörz D; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Emmerich P; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Straße 74, 20359, Hamburg, Germany., von Possel R; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Straße 74, 20359, Hamburg, Germany., Giersch K; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Pflüger LS; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Bernreuther C; Institute of Pathology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Glatzel M; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Krasemann S; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.; Core Facility for (Mouse) Pathology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Brehm TT; Division of Infectious Diseases, I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, 20246, Hamburg, Germany., Schulze Zur Wisch J; Division of Infectious Diseases, I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, 20246, Hamburg, Germany., Fischer N; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Schmiedel S; Division of Infectious Diseases, I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany., Aepfelbacher M; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Lütgehetmann M; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.

Publikováno v: Heliyon [Heliyon] 2024 Oct 04; Vol. 10 (19), pp. e38873. Date of Electronic Publication: 2024 Oct 04 (Print Publication: 2024).

Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases.

Autor: Song F; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Kovac V; Centre for Immunology and Development, Blood Transfusion Centre of Slovenia (BTCS), Ljubljana, Slovenia., Mohammadi B; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Littau JL; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Scharfenberg F; Institute of Biochemistry, University of Kiel, Kiel, Germany., Matamoros Angles A; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Vanni I; Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità, Rome, Italy., Shafiq M; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Orge L; National Institute for Agricultural and Veterinary Research (INIAV), Oeiras, Portugal.; Animal and Veterinary Research Centre (CECAV), University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal., Galliciotti G; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Djakkani S; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Linsenmeier L; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Černilec M; Centre for Immunology and Development, Blood Transfusion Centre of Slovenia (BTCS), Ljubljana, Slovenia., Hartman K; Centre for Immunology and Development, Blood Transfusion Centre of Slovenia (BTCS), Ljubljana, Slovenia., Jung S; Department of Biochemistry of Neurodegenerative Diseases, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Tatzelt J; Department of Biochemistry of Neurodegenerative Diseases, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany.; Cluster of Excellence RESOLV, Ruhr University Bochum, Bochum, Germany., Neumann JE; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.; Center for Molecular Neurobiology Hamburg (ZMNH), UKE, Hamburg, Germany., Damme M; Institute of Biochemistry, University of Kiel, Kiel, Germany., Tschirner SK; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine and Health, Klinikum rechts der Isar, Technical University Munich, 81675, Munich, Germany., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine and Health, Klinikum rechts der Isar, Technical University Munich, 81675, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Ricklefs FL; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Sauvigny T; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Schmitz M; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany., Zerr I; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany., Puig B; Department of Neurology, Experimental Research in Stroke and Inflammation (ERSI), UKE, Hamburg, Germany., Tolosa E; Department of Immunology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Ferrer I; Department of Pathology and Experimental Therapeutics, University of Barcelona, IDIBELL, Hospitalet de Llobregat, Spain., Magnus T; Department of Neurology, Experimental Research in Stroke and Inflammation (ERSI), UKE, Hamburg, Germany., Rupnik MS; Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria., Sepulveda-Falla D; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Matschke J; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Šmid LM; LNPR, Institute of Pathophysiology and Prion Laboratory, Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Bresjanac M; LNPR, Institute of Pathophysiology and Prion Laboratory, Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Andreoletti O; UMR INRAE ENVT 1225, Interactions Hôtes-Agents Pathogènes, École Nationale Vétérinaire de Toulouse, Toulouse, France., Krasemann S; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Foliaki ST; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, Hamilton, MT, USA., Nonno R; Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità, Rome, Italy., Becker-Pauly C; Institute of Biochemistry, University of Kiel, Kiel, Germany., Monzo C; Institute for Regenerative Medicine and Biotherapies (IRMB), Neural Stem Cell, MSC and Neurodegenerative Diseases, INSERM, Montpellier, France., Crozet C; Institute for Regenerative Medicine and Biotherapies (IRMB), Neural Stem Cell, MSC and Neurodegenerative Diseases, INSERM, Montpellier, France., Haigh CL; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, Hamilton, MT, USA., Glatzel M; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Curin Serbec V; Centre for Immunology and Development, Blood Transfusion Centre of Slovenia (BTCS), Ljubljana, Slovenia. vladka.curin@ztm.si., Altmeppen HC; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany. h.altmeppen@uke.de.

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2024 Jul 09; Vol. 148 (1), pp. 2. Date of Electronic Publication: 2024 Jul 09.