Zobrazeno 1 - 10
of 765
pro vyhledávání: '"S Kirkpatrick"'
Publikováno v:
California Agriculture, Vol 74, Iss 3 (2020)
Monterey pine (Pinus radiata) is a species of limited distribution, with three native populations in California. In 1986, a disease known as pitch canker, caused by the fungus Fusarium circinatum, was identified as the cause of extensive mortality in
Externí odkaz:
https://doaj.org/article/30d4928605964091aee9ba82f0cbcd23
Publikováno v:
California Agriculture, Vol 66, Iss 1 (2012)
Fusarium wilt of lettuce, caused by the soilborne fungus Fusarium oxysporum f. sp. lactucae, affects all major lettuce production areas in California and Arizona. In trials at UC Davis, we found that lettuce cultivars differ significantly in suscepti
Externí odkaz:
https://doaj.org/article/41f5ffd4ad994f3fa87cedded263b871
Publikováno v:
California Agriculture, Vol 64, Iss 1 (2010)
Since 1994, more than 480 genotypes from the UC strawberry breeding program have been screened for resistance to Verticillium dahliae Kleb., an important soil pathogen of strawberry. Genotypes for parents of subsequent generations have been chosen us
Externí odkaz:
https://doaj.org/article/6797508b28ab45bfbd5a5e0207914140
Autor:
Christopher W. Davies, Simon E. Vidal, Lilian Phu, Jawahar Sudhamsu, Trent B. Hinkle, Scott Chan Rosenberg, Frances-Rose Schumacher, Yi Jimmy Zeng, Carsten Schwerdtfeger, Andrew S. Peterson, Jennie R. Lill, Christopher M. Rose, Andrey S. Shaw, Ingrid E. Wertz, Donald S. Kirkpatrick, James T. Koerber
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
UBE2W catalyzes the ubiquitination of protein N-termini but its substrate spectrum is largely unknown. Here, the authors discover mAbs selective for peptides derived from N-terminally ubiquitinated proteins, solve the structure of a peptide-bound mAb
Externí odkaz:
https://doaj.org/article/cbfb2674260f4b51a1c495c83e07dcb5
Autor:
Kimberly Stark, Tatiana Goncharov, Eugene Varfolomeev, Luke Xie, Hai Ngu, Ivan Peng, Keith R. Anderson, Erik Verschueren, Meena Choi, Donald S. Kirkpatrick, Amy Easton, Joshua D. Webster, Brent S. McKenzie, Domagoj Vucic, Baris Bingol
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Abstract RIP1 kinase-mediated inflammatory and cell death pathways have been implicated in the pathology of acute and chronic disorders of the nervous system. Here, we describe a novel animal model of RIP1 kinase deficiency, generated by knock-in of
Externí odkaz:
https://doaj.org/article/c403fe72c3fe41429f8c35b23860a00f
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021)
Abstract Background To report the occurrence of tophaceous gout in the cervical spine and to review the literature on spinal gout. Case presentation This report details the occurrence of a large and clinically significant finding of tophaceous gout i
Externí odkaz:
https://doaj.org/article/16013739626741ad8f84cb600ab97758
Autor:
Avinashnarayan Venkatanarayan, Jason Liang, Ivana Yen, Frances Shanahan, Benjamin Haley, Lilian Phu, Erik Verschueren, Trent B. Hinkle, David Kan, Ehud Segal, Jason E. Long, Tony Lima, Nicholas P.D. Liau, Jawahar Sudhamsu, Jason Li, Christiaan Klijn, Robert Piskol, Melissa R. Junttila, Andrey S. Shaw, Mark Merchant, Matthew T. Chang, Donald S. Kirkpatrick, Shiva Malek
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110351- (2022)
Summary: KRAS, which is mutated in ∼30% of all cancers, activates the RAF-MEK-ERK signaling cascade. CRAF is required for growth of KRAS mutant lung tumors, but the requirement for CRAF kinase activity is unknown. Here, we show that subsets of KRAS
Externí odkaz:
https://doaj.org/article/fa5d3d0fa6ab4799a1b8b428959ad8e4
Autor:
Kelvin F. Cho, Taylur P. Ma, Christopher M. Rose, Donald S. Kirkpatrick, Kebing Yu, Robert A. Blake
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Quantitative profiling of small molecule-protein binding in cells can aid basic biochemical research and drug discovery. Here, the authors develop the Heat Shock Protein Inhibition Protein Stability Assay (HIPStA) as a high-throughput method to asses
Externí odkaz:
https://doaj.org/article/d8e4230757ef4fa5aa0391581b106a4b
Publikováno v:
Obesity Science & Practice, Vol 5, Iss 5, Pp 468-478 (2019)
Summary Objective This retrospective study aimed to evaluate the impact of anti‐obesity medication (AOM) initiation, usage and duration on weight loss in a 72‐week precision obesity programme. The type of AOM, diet and exercise plan was chosen ba
Externí odkaz:
https://doaj.org/article/6c065d8d94f446e886fa644c61e32edb
Autor:
Arundhati Sengupta-Ghosh, Sara L. Dominguez, Luke Xie, Kai H. Barck, Zhiyu Jiang, Timothy Earr, Jose Imperio, Lilian Phu, Hanna G. Budayeva, Donald S. Kirkpatrick, Hao Cai, Jeffrey Eastham-Anderson, Hai Ngu, Oded Foreman, Maj Hedehus, Michael Reichelt, Isidro Hotzel, Yonglei Shang, Richard A.D. Carano, Gai Ayalon, Amy Easton
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 340-352 (2019)
Amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting motor neurons, is characterized by rapid decline of motor function and ultimately respiratory failure. As motor neuron death occurs late in the disease, therapeutics that prev
Externí odkaz:
https://doaj.org/article/cd3e464eb6fd4c10b7ea4c66731e7e28