Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S K van den Hengel"'
Autor:
Taco Gilles Uil, Carla S Verissimo, Rob C. Hoeben, Steve J. Cramer, J de Vrij, S K van den Hengel, Jort Vellinga, Iris J. C. Dautzenberg, Maria K. Magnusson, Danijela Koppers-Lalic, Leif Lindholm
Publikováno v:
Gene Therapy, 19(9), 899-906
Human adenoviruses have a great potential as anticancer agents. One strategy to improve their tumor-cell specificity and anti-tumor efficacy is to include tumor-specific targeting ligands in the viral capsid. This can be achieved by fusion of polypep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68d31c7c694ef050ebfbdd92e160b2d
https://doi.org/10.1038/gt.2011.162
https://doi.org/10.1038/gt.2011.162
Autor:
Iris J. C. Dautzenberg, S K van den Hengel, Onno Kranenburg, Rob C. Hoeben, D J M van den Wollenberg, Steve J. Cramer
Publikováno v:
Gene Therapy. 15:1567-1578
Human Orthoreovirus Type 3 Dearing is not pathogenic to humans and has been evaluated clinically as an oncolytic agent. Its transduction efficiency and the tumor cell selectivity may be enhanced by incorporating ligands for alternative receptors. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3937153a1dcb5f173126a40f8d0800d6
https://doi.org/10.1038/gt.2008.118
https://doi.org/10.1038/gt.2008.118
Autor:
S K van den Hengel, Jort Vellinga, Rob C. Hoeben, Taco Gilles Uil, Emmanuel J. H. J. Wiertz, Ralph A. Willemsen, Steve J. Cramer, Marieke C. Verweij, Danijela Koppers-Lalic, J de Vrij
Publikováno v:
Gene Therapy, 15(13), 978-989. Nature Publishing Group
Adenovirus vectors have great potential in cancer gene therapy. Targeting of cancer-testis (CT) antigens, which are specifically presented at the surface of tumor cells by human leukocyte antigen (HLA) class I molecules, is an attractive option. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7b61f99dd5cc602d7f524283ca83b3
https://doi.org/10.1038/gt.2008.26
https://doi.org/10.1038/gt.2008.26
Autor:
W Ros, A D Lipińska, Iris J. C. Dautzenberg, S K van den Hengel, D J M van den Wollenberg, Rob C. Hoeben
Publikováno v:
Gene Therapy, 22(3), 267-279
The capacity to modify the reovirus genome facilitates generation of new therapeutic reoviruses. We describe a method for generating replication-competent reoviruses carrying a heterologous transgene. The strategy is based on the expanded-tropism reo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a8e147a0a434cf148815e72df8f83b
https://hdl.handle.net/1887/105668
https://hdl.handle.net/1887/105668
Autor:
D J M van den Wollenberg, Iris J. C. Dautzenberg, Montserrat Bárcena, Rob C. Hoeben, S K van den Hengel, Abraham J. Koster, Ronald W. A. L. Limpens
Publikováno v:
Gene Therapy, 21(6), 609-617
In the canonical pathway, infection of cells by the wild-type mammalian orthoreovirus Type 3 Dearing (T3D) is dependent on the interaction of the viral spike protein σ1 with the high-affinity cellular receptor junction adhesion molecule-A (JAM-A). W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4366db61ebe2f5c0bbd8c1cb5164f885
https://doi.org/10.1038/gt.2014.34
https://doi.org/10.1038/gt.2014.34