Zobrazeno 1 - 10
of 40
pro vyhledávání: '"S K Moestrup"'
Autor:
L. R. Rega, V. Janssens, J. H. Graversen, S. K. Moestrup, S. Cairoli, B. M. Goffredo, N. Nevo, G. E. Courtoy, F. Jouret, C. Antignac, F. Emma, C. E. Pierreux, P. J. Courtoy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Megalin/LRP2 is a major receptor supporting apical endocytosis in kidney proximal tubular cells. We have previously reported that kidney-specific perinatal ablation of the megalin gene in cystinotic mice, a model of nephropathic cystinosis,
Externí odkaz:
https://doaj.org/article/fe411d3fc3094a429459fbda156c7a31
Autor:
A. M. Kivelä, J. Huusko, E. Gurzeler, A. Laine, M. H. Dijkstra, G. Dragneva, C. B. F. Andersen, S. K. Moestrup, S. Ylä-Herttuala
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Adenoviruses are very efficient vectors for delivering therapeutic genes in preclinical and clinical trials. However, randomized controlled human trials have often been lacking clear clinically relevant results. We hypothesized that high lip
Externí odkaz:
https://doaj.org/article/13eec640ea744d0e8b268a995fb998d0
Autor:
Nanna MacAulay, Takwa S. Aroankins, Joachim Slengerik-Hansen, Vivek Bhalla, Mette Assentoft, Robert A. Fenton, S K Moestrup, Hanne B. Moeller
Publikováno v:
Moeller, H B, Slengerik-Hansen, J, Aroankins, T, Assentoft, M, MacAulay, N, Moestrup, S K, Bhalla, V & Fenton, R A 2016, ' Regulation of the Water Channel Aquaporin-2 via 14-3-3θ and-ζ ', Journal of Biological Chemistry, vol. 291, no. 5, pp. 2469-84 . https://doi.org/10.1074/jbc.M115.691121
Moeller, H B, Slengerik-Hansen, J, Aroankins, T, Assentoft, M, MacAulay, N, Moestrup, S K, Bhalla, V & Fenton, R A 2016, ' Regulation of the Water Channel Aquaporin-2 via 14-3-3θ and-ζ ', Journal of Biological Chemistry, vol. 291, no. 5, pp. 2469-2484 . https://doi.org/10.1074/jbc.M115.691121
Moeller, H B, Slengerik-Hansen, J, Aroankins, T, Assentoft, M, MacAulay, N, Moestrup, S K, Bhalla, V & Fenton, R A 2016, ' Regulation of the Water Channel Aquaporin-2 via 14-3-3θ and-ζ ', Journal of Biological Chemistry, vol. 291, no. 5, pp. 2469-2484 . https://doi.org/10.1074/jbc.M115.691121
The 14-3-3 family of proteins are multifunctional proteins that interact with many of their cellular targets in a phosphorylation-dependent manner. Here, we determined that 14-3-3 proteins interact with phosphorylated forms of the water channel aquap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d97451ee82cbc7d73fd58ce4f0a416
https://pure.au.dk/portal/da/publications/regulation-of-the-water-channel-aquaporin2-via-1433-and-(670ee6f0-d3fc-421d-97c3-35544c61d9d6).html
https://pure.au.dk/portal/da/publications/regulation-of-the-water-channel-aquaporin2-via-1433-and-(670ee6f0-d3fc-421d-97c3-35544c61d9d6).html
Autor:
Maria Aminoff, Lasse Jenner, Jo Ellen Carter, S K Moestrup, Pierre J. Verroust, Cheryl K. Johnson, Harald Broch, Ralf Krahe, Mohamed A. Abdelaal, Robert B. Chadwick, Ralph Gräsbeck, Albert de la Chapelle
Publikováno v:
Nature Genetics. 21:309-313
Megaloblastic anaemia 1 (MGA1, OMIM 261100) is a rare, autosomal recessive disorder characterized by juvenile megaloblastic anaemia, as well as neurological symptoms that may be the only manifestations. At the cellular level, MGA1 is characterized by
Autor:
E. I. Christensen, Jörg-Robert Leheste, I Schousboe, Christian Jacobsen, S K Moestrup, Thomas E. Willnow
Publikováno v:
Journal of Clinical Investigation. 102:902-909
Screening of serum by using a surface plasmon resonance analysis assay identified beta2-glycoprotein-I/apolipoprotein H as a plasma component binding to the renal epithelial endocytic receptor megalin. A calcium-dependent megalin-mediated beta2-glyco
Publikováno v:
Annals of the New York Academy of Sciences. 737:202-211
Autor:
Hans Christian Thøgersen, Peter A. Andreasen, Michael Etzerodt, Anders Nykjaer, Lars Sottrup-Jensen, Thor Las Holtet, H. H. Rasmussen, Jørgen Gliemann, S K Moestrup
Publikováno v:
Moestrup, S K, Holtet, T L, Etzerodt, M, Thøgersen, H C, Nykjær, A, Andreasen, P, Rasmussen, H H, Sottrup-Jensen, L & Gliemann, J 1993, ' Alpha 2-macroglobulin-proteinase complexes, plasminogen activator inhibitor type-1-plasminogen activator complexes, and receptor-associated protein bind to a region of the alpha(2)-Macroglobulin receptor containing a cluster of eight complement-type repeats ', Journal of Biological Chemistry, vol. 268, no. 18, pp. 13691-13696 .
A region containing sites for ligand binding was localized in the 4525-amino acid residue alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (alpha 2MR/LRP) by ligand- and immunoblotting of proteinase and CNBr digests of
Autor:
Bjarne Kuno Møller, Michael Etzerodt, Poul Henning Jensen, S K Moestrup, Peter A. Andreasen, Anders Nykjaer, Thor Las Holtet, Mette Munch, Hans Christian Thøgersen, Claus Munck Petersen
Publikováno v:
Journal of Biological Chemistry. 267:14543-14546
Complexes between 125I-labeled urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1) bound to purified alpha 2-macroglobulin (alpha 2M) receptor (alpha 2MR)/low density lipoprotein receptor-related protein (LRP
Autor:
Jørgen Gliemann, S K Moestrup
Publikováno v:
Journal of Biological Chemistry. 266:14011-14017
The molecular basis for binding of alpha-macroglobulin-proteinase complexes to the human two-chain 500/85-kDa (alpha/beta) alpha 2-macroglobulin (alpha 2M) receptor (alpha 2MR)/low density lipoprotein receptor-related protein was analyzed. Ligand blo
Autor:
S K Moestrup, Hans Christian Thøgersen, Jørgen Gliemann, Lars Sottrup-Jensen, Thor Las Holtet, Michael Etzerodt, Kåre Lehmann Nielsen
Publikováno v:
Annals of the New York Academy of Sciences. 737:480-482