Zobrazeno 1 - 10
of 27
pro vyhledávání: '"S K Durum"'
Publikováno v:
European Urology. 39:478-483
Immunochemotherapy (ICT) with interleukin-2 (IL-2) and interferon-alpha (IFNalpha) with a secondary effector (5-fluorouracil, 5 FU) is the only promising treatment for advanced renal cell carcinoma (RCC). With IFNalpha, besides the activation mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d87ba20331acdafebafbb4ca1aaefdb
https://doi.org/10.1159/000052489
https://doi.org/10.1159/000052489
Publikováno v:
Proceedings of the National Academy of Sciences. 90:7054-7058
Interleukin 1 (IL-1) induces pleiotropic effects in many cell types during inflammation and immunity. We have recently shown how the IL-1 signal is transmitted to the nucleus: In T cells and in pituitary cells, IL-1 induced genes via activation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befe29c84c14a71521dcd29d7052c29e
https://doi.org/10.1073/pnas.90.15.7054
https://doi.org/10.1073/pnas.90.15.7054
Publikováno v:
The Journal of Immunology. 149:3851-3857
Growth hormone (GH) and other neuroendocrine mediators have been implicated previously in T cell development. We therefore examined thymic development in DW/J dwarf mice. DW/J mice lack acidophilic anterior pituitary cells and consequently are totall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7d59f4a4a3b5972bd42e30e0f6082ef
https://doi.org/10.4049/jimmunol.149.12.3851
https://doi.org/10.4049/jimmunol.149.12.3851
Publikováno v:
The Journal of Immunology. 149:1304-1310
Macrophages are activated by a variety of microbial and cytokine stimuli. One feature of activation is the induction of class II Ag (Ia) on the cell surface. To understand the intracellular events that occur during activation, we investigated various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::499ca5c945edc96beab73ec25533c54e
https://doi.org/10.4049/jimmunol.149.4.1304
https://doi.org/10.4049/jimmunol.149.4.1304
Publikováno v:
The Journal of Immunology. 148:3799-3805
DW/J dwarf mice lack acidophilic anterior pituitary cells and are deficient in growth hormone and other neuroendocrine mediators. These mice were examined to determine the effects of these deficiencies on hematopoietic and immune system development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d2c294e6b6fc081cb1e6c9fead1163e
https://doi.org/10.4049/jimmunol.148.12.3799
https://doi.org/10.4049/jimmunol.148.12.3799
Publikováno v:
The Journal of Immunology. 146:2262-2271
The sequence of activation signals that stimulate proliferation, differentiation, and selection of mature T cell subsets from immature, dull-CD5+/CD4-, CD8- double negative (bCD5), (dCD5/DN) thymocytes are still unclear. However, it is likely that cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc2dc7f18a9b1c283e74d6b9193cb627
https://doi.org/10.4049/jimmunol.146.7.2262
https://doi.org/10.4049/jimmunol.146.7.2262
Publikováno v:
The Journal of Immunology. 146:1509-1515
IL-1 alpha regulation of ornithine decarboxylase (ODC) was examined in T cells because IL-1 is a costimulus for T cell proliferation and ODC is a critical enzyme in the metabolic events associated with cellular proliferation. In the present study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee2754542be1623ac13d453777c113f1
https://doi.org/10.4049/jimmunol.146.5.1509
https://doi.org/10.4049/jimmunol.146.5.1509
Publikováno v:
The Journal of Immunology. 145:4108-4114
IL-1 is a co-stimulus for T cell proliferation along with TCR cross-linking agents or lectins. Here we demonstrate that IL-1 alpha, in the absence of a TCR stimulus, induces active TGF-beta production by non-proliferating T cells. Thus, in addition t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58837d9f590eea3cdb6f1b0bbbb3de73
https://doi.org/10.4049/jimmunol.145.12.4108
https://doi.org/10.4049/jimmunol.145.12.4108
Publikováno v:
The Journal of Immunology. 144:2572-2581
Fixation of APC with 1-ethyl-3-(3-dimethylamino-propyl)carbodiimide (ECDI) eliminates their ability to stimulate proliferation of alloreactive T cells or the D10 T cell clone, although a partial response, IL-4 production, was measured. However, if AP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::725b0efdcbab49a69b3f240a4b31b762
https://doi.org/10.4049/jimmunol.144.7.2572
https://doi.org/10.4049/jimmunol.144.7.2572
Publikováno v:
The Journal of Immunology. 144:1777-1782
An intracellular action for IFN-gamma was detected by using microinjection technology. Human IFN-gamma (huIFN-gamma) does not ordinarily act on murine cells because it fails to bind to murine cell surface receptors. However, when huIFN-gamma was micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608f5200c8f4e83c04d9afd8156330ee
https://doi.org/10.4049/jimmunol.144.5.1777
https://doi.org/10.4049/jimmunol.144.5.1777