Zobrazeno 1 - 10
of 75
pro vyhledávání: '"S K Dower"'
Publikováno v:
Cytokine & Growth Factor Reviews. 15:97-102
Advances in high throughput sequencing technologies have led to an explosion of sequence information available for today's researchers. Efforts in the emerging next phase of the genomic era are focusing on the assignment of function to genes uncovere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4178952d8d2bbe46331c39439fb7fc36
https://doi.org/10.1016/j.cytogfr.2004.02.002
https://doi.org/10.1016/j.cytogfr.2004.02.002
Autor:
J G Giri, J Wells, S K Dower, C E McCall, R N Guzman, J Slack, T A Bird, K Shanebeck, K H Grabstein, J E Sims
Publikováno v:
The Journal of Immunology. 153:5802-5809
Two types of cellular IL-1Rs have been characterized and cloned from both human and murine sources. The type II IL-1R has a very short cytoplasmic domain and does not seem to participate in IL-1 signaling. We demonstrate that type II IL-1Rs are relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152e718ee5a733425125233e6b832c4c
https://doi.org/10.4049/jimmunol.153.12.5802
https://doi.org/10.4049/jimmunol.153.12.5802
Publikováno v:
The Journal of Immunology. 153:4766-4774
These studies have examined the binding of the three IL-1 ligands, IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist (IL-1 ra), to soluble forms of types I and II IL-1Rs (sIL-1RI and sIL-1RII). This interaction was measured in direct binding experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6e6e7c52d04685bf062e8a49730000c
https://doi.org/10.4049/jimmunol.153.10.4766
https://doi.org/10.4049/jimmunol.153.10.4766
Autor:
S Nagoya, P D Greenberg, C Yee, K E Weisser, H Sugawara, M B Widmer, J Slack, S K Dower, S D Lupton, R W Overell
Publikováno v:
The Journal of Immunology. 153:1527-1535
Although the proliferation of CD8+ CTL typically requires cytokine support provided by helper T cells, a subset of naturally occurring CD8+ CTL are capable of proliferating independently of T cell help. Such helper-independent CTL have previously bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac547dc6fa8ef81dfc72b5f3b7e1f543
https://doi.org/10.4049/jimmunol.153.4.1527
https://doi.org/10.4049/jimmunol.153.4.1527
Autor:
L L Gill, Gerold Schuler, F Koch, Andreas O. Eggert, C Heufler, Nikolaus Romani, S K Dower, Eckhart Kämpgen, S Gillis
Publikováno v:
The Journal of Experimental Medicine
Dendritic cells form a system of antigen presenting cells that are specialized to stimulate T lymphocytes, including quiescent T cells. The lineage of dendritic cells is not fully characterized, although prior studies have shown that growth and diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c8f4a1a9d72072487c6e8922948828
https://doi.org/10.1084/jem.179.6.1767
https://doi.org/10.1084/jem.179.6.1767
Autor:
K Poindexter, David Cosman, R Jerzy, V Lum, Kronheim S, Hopp Tp, S K Dower, Amanda L. Lewis, S Gillis, R. B. Gayle
Publikováno v:
Journal of Biological Chemistry. 268:22105-22111
Saturation mutagenesis of the mature human interleukin-1 alpha (IL-1 alpha) gene has been performed. Following expression in Escherichia coli, the biological and receptor binding activities of the mutant proteins were examined. Most of the molecule c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40ab2a0c4d441230bf11a67cd4c7f7d
https://doi.org/10.1016/s0021-9258(20)80654-1
https://doi.org/10.1016/s0021-9258(20)80654-1
Publikováno v:
Journal of Biological Chemistry. 268:2513-2524
Interleukin (IL)-1 refers to a group of three polypeptide hormones with a wide range of cellular targets. Two types of IL-1 receptor have been identified and characterized by cDNA cloning. Both human type I and type II IL-1 receptors contain extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::804f236c94f6423fe5ee95cf9309ce08
https://doi.org/10.1016/s0021-9258(18)53806-0
https://doi.org/10.1016/s0021-9258(18)53806-0
Autor:
Carol Hopkins Sibley, S K Dower, J E Sims, Kathryn E. Meier, Karol Bomsztyk, Mary A. Valentine, Jerzy Ostrowski
Publikováno v:
Journal of Biological Chemistry. 266:12722-12733
The immunoglobulin kappa light chain enhancer, kappa B, is an important cis-acting transcriptional element. kappa B binds a number of proteins including the members of the ubiquitous NF-kappa B family of transcription factors. Agarose beads coupled t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7b2485bb25d8a6b6381eb637c0f04f6
https://doi.org/10.1016/s0021-9258(18)98959-3
https://doi.org/10.1016/s0021-9258(18)98959-3
Publikováno v:
Scopus-Elsevier
Primary human monocytes and the human monocytic cell line THP-1 were induced to express receptors for interleukin-1 alpha (IL-1 alpha) and IL-1 beta. Treatment of primary monocytes with dexamethasone resulted in a 10-fold increase in receptor number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8ce53a489beda49b30c883a026bd72
https://doi.org/10.1016/s0021-9258(18)45733-x
https://doi.org/10.1016/s0021-9258(18)45733-x
Publikováno v:
Journal of Biological Chemistry. 265:9943-9951
IL-1 alpha and IL-1 beta although distantly related at the primary sequence level, bind to the same Mr 80,000 IL-1 receptor on various cell types. Several lines of evidence indicate, however, that the IL-1 receptor on B cells and T cells differ. By b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404da1389f48fb50b194a297a5abb95c
https://doi.org/10.1016/s0021-9258(19)38762-9
https://doi.org/10.1016/s0021-9258(19)38762-9