Zobrazeno 1 - 10
of 26
pro vyhledávání: '"S K Chapes"'
Publikováno v:
Journal of Applied Physiology. 78:968-975
Antiorthostatically suspended mice had suppressed macrophage development in both unloaded and loaded bones, indicating a systemic effect. Bone marrow cells from those mice secreted less macrophage colony-stimulating factor (M-CSF) and interleukin-6 (
Publikováno v:
The Journal of Immunology. 145:1505-1511
We have investigated the relative immunostimulatory activities of S-chemotype LPS and R-chemotype LPS preparations on C3H/HeJ peritoneal macrophages in vitro. As assessed by either secretion of TNF-alpha or IL-1, some of the R-chemotype LPS manifest
Autor:
S K, Chapes
Publikováno v:
Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology. 11(2)
Sprague-Dawley rats were subjected to three 8-to-10 day space flights on the Space Shuttle. Housed in NASA's Animal Enclosure Modules, rats were flown to test the hypotheses that therapy with pegylated interleukin-2 or insulin-like growth factor-1 wo
Autor:
Patricia W, Stewart, S K, Chapes
Publikováno v:
Comparative medicine. 53(1)
Genetics plays a substantial role in host resistance in many host-parasite interactions. We examined the prevalence of naturally acquired infection with Syphacia obvelata in a number of mouse strains housed in a non-barrier facility. These mice, whic
Publikováno v:
Biomedical sciences instrumentation. 38
We investigated the effect of major histocompatibility complex class II (MHC II) knockout on the development of the mouse peripheral skeleton. These C2D mice had less skeletal development at 8, 12 and 16 weeks of age compared to wild-type C57BL/6J (B
Publikováno v:
Journal of leukocyte biology. 69(3)
MHCII, Tlr4, and Nramp1 genes are each independently important in pulmonary immunity. To determine the effect of these genes on host resistance, mice carrying various combinations of functional alleles for these three genes were experimentally challe
Autor:
S R, Monday, G M, Vath, W A, Ferens, C, Deobald, J V, Rago, P J, Gahr, D D, Monie, J J, Iandolo, S K, Chapes, W C, Davis, D H, Ohlendorf, P M, Schlievert, G A, Bohach
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(8)
Certain strains of Staphylococcus aureus express one or both of two related, but immunologically distinct, exfoliative toxins (ETA and ETB). These toxins induce the symptoms associated with staphylococcal scalded skin syndrome. Both ETs have been sho
Publikováno v:
Investigative ophthalmologyvisual science. 38(6)
Keratan sulfate proteoglycans (KSPGs) of the cornea exhibit a characteristic change in glycosylation resulting from stromal inflammation and scarring. To examine potential roles for these molecules in the pathobiology of the cornea, the authors inves
Publikováno v:
Transactions of the Kansas Academy of Science. Kansas Academy of Science. 96(1-2)
This manuscript briefly reviews ground-based and flight experiments, discusses how those experiments complement each other, and details how those experiments lead us to speculate about the gravity-sensitive nature of protein kinase C.
Publikováno v:
Regional immunology. 4(4)
Pulmonary intravascular macrophages (PIMs) are lung macrophages found apposed to the endothelium of pulmonary capillaries. In many species, they are responsible for the clearance of blood-borne particulates and pathogens; however, little else is know