Výsledky vyhledávání - "S K, Koester"

APO2.7 defines a shared apoptotic-necrotic pathway in a breast tumor hypoxia model

Autor: S K, Koester, S F, Schlossman, C, Zhang, S J, Decker, W E, Bolton

Publikováno v: Cytometry. 33(3)

A breast tumor hypoxia model used to simulate conditions which may exist within an enlarging tumor was examined using documented methods for identifying mechanisms of cell death and compared to the mitochondrial membrane-specific APO2.7 antigen expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24e506d03c2a9fc4c8b9d05b216479e5
https://pubmed.ncbi.nlm.nih.gov/9822343

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Monitoring early cellular responses in apoptosis is aided by the mitochondrial membrane protein-specific monoclonal antibody APO2.7

Autor: S K, Koester, P, Roth, W R, Mikulka, S F, Schlossman, C, Zhang, W E, Bolton

Publikováno v: Cytometry. 29(4)

A recently described mitochondrial membrane protein-specific monoclonal antibody, APO2.7, was examined for monitoring early apoptotic responses in anti-CD95 (7C11)-induced Jurkat cells. Jurkat cells were harvested at 1.5, 3, 4.5, 6, 12, and 18 h afte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::edb2660c92744746eb721beca23ece75
https://pubmed.ncbi.nlm.nih.gov/9415413

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Discrimination of late apoptotic/necrotic cells (type III) by flow cytometry in solid tumors

Autor: M C, O'Brien, S F, Healy, S R, Raney, J M, Hurst, B, Avner, A, Hanly, C, Mies, J W, Freeman, C, Snow, S K, Koester, W E, Bolton

Publikováno v: Cytometry. 28(1)

A method is described for the discrimination of Type III, late apoptotic, and necrotic cells, to improve the accuracy of proliferation and ploidy determinations of breast tumors. We selected an immunological probe, antitubulin antibody, and a DNA spe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bb4b48ac6893bf12dd756b8ae8b2ea75
https://pubmed.ncbi.nlm.nih.gov/9136759

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Toremifene enhances cell cycle block and growth inhibition by vinblastine in multidrug resistant human breast cancer cells

Autor: W J, Baker, J U, Maenpaa, G T, Wurz, S K, Koester, R C, Seymour, V D, Emshoff, V J, Wiebe, M W, DeGregorio

Publikováno v: Oncology research. 5(6-7)

The clinical study of compounds that modulate multidrug resistance has been hindered by both the toxicities of these agents and the inability to monitor their effectiveness at the level of the tumor cell. Previously, toremifene has been shown to be w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::97933ef278e4735431fc52111e1ce079
https://pubmed.ncbi.nlm.nih.gov/8123940

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A breast cancer clone selected by tamoxifen has increased growth rate and reduced sensitivity to doxorubicin

Autor: J U, Maenpaa, G T, Wurz, W J, Baker, V J, Wiebe, V D, Emshoff, S K, Koester, R C, Seymour, R E, Koehler, M W, DeGregorio

Publikováno v: Oncology research. 5(12)

The in vivo growth rate and the chemosensitivity patterns of a cell clone selected by tamoxifen from the estrogen receptor-negative human breast cancer cell line MDA-MB-231 was studied in the nude mouse model and with flow cytometry. To investigate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9c44e8903a200d55b30a411c69e877e
https://pubmed.ncbi.nlm.nih.gov/8086667

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Treatment-induced changes in sensitivity in a multiclonal human tumor mixture model in vitro

Autor: S C, Barranco, C M, Townsend, V K, Jenkins, S K, Koester, B Y, Ho, K J, Reumont

Publikováno v: Cancer research. 48(10)

An in vitro model has been devised so that mixtures of human tumor cells can be grown together for studies related to drug-induced or -selected changes in sensitivity. In the studies reported here, two human astrocytoma clones, one sensitive and one

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4dab5db467a964d70d7ed92e3063e697
https://pubmed.ncbi.nlm.nih.gov/3359435

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