Zobrazeno 1 - 10
of 35
pro vyhledávání: '"S K, Karsanova"'
Autor:
V V, Yasnetsov, E G, Tsublova, Vic V, Yasnetsov, S Ya, Skachilova, S K, Karsanova, Yu V, Ivanov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 79(2)
It was established that a new 3-hydroxypyridine (3-HP) derivative, 2-ethyl-6-methyl-3-hydroxypyridine L-aspartate (3-HP), in small doses (1 and 5 mg/kg) increased physical performance in treadmill and swimming tests on rats. The new substance showed
Autor:
V V, Yasnetsov, E G, Tsublova, Vik V, Yasnetsov, S Ya, Skachilova, S K, Karsanova, N A, Chelnaya
Publikováno v:
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 49(6)
In experiments with rats, a new 3-hydroxypyridine (3-HP) derivative--2-ethyl-6-methyl-3-hydroxypyridine L-asparaginate (30 mg/kg)--exhibited a strong vestibuloprotective effect which was better than of promethazine (50 mg/kg), a well-known vestibulop
Publikováno v:
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 49(5)
Experiments with mice showed that in a multitude of acute hypoxia models (normobaric hypoxic hypoxia with hypercapnia, hypobaric, hemic and histotaxic) the antihypoxic action of a single intra-abdominal dose of melatonin surpasses greatly amtisol, th
Publikováno v:
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 49(1)
The results of experimental clinical testing of the antinaupathia action of as new compounds, so motion sickness medications (promethazine, ikaron-1 etc.) are presented. Russian medication mexidol, a derivative of 3-hydroxypyridine (3-HP) demonstrate
Publikováno v:
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 48(6)
In experiments with cats, air-assisted microinjections of mexidol and melatonin had a direct effect on 71-81% Purkinje cells inducing the inhibitory response 4.2-6.3 times more often than exiting. In case of concurrent action of MK-801 (a specific no
Autor:
Iasnetsov, A A, Ozerov, V G, Motin, Vik V, Iasnetsov, S K, Karsanova, Iu V, Ivanov, N A, Chel'naia
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 77(10)
It is established that the new compound, 9-[2-(4-isopropylphenoxy)ethyl]adenine (9-IPE-adenine) in a dose of 10 mg/kg per day produces neuroprotective effect in rats with brain ischemia model. 9-IPE-adenine decreased the neurologic deficiency 1.2 tim
Publikováno v:
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 48(2)
Experiments with rats showed that melatonin (2.5 mg/kg) produces a distinct vestibular protective effect excelling promethazine (50 mg/kg) as a reference agent, and also antidepressant agomelatine (5 mg/kg) as another melatoninergic agent. Lusindol,
Publikováno v:
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 47(2)
Pneumomicroinjection of vestibuloprotector ikaron-1 (Russia) in specific neurons of the medial vestibular nucleus (MVN) was studied in cats immobilized by muscle relaxants using microelectrode devices. The original preparation had a direct effect on
Autor:
Vic V, Iasnetsov, E P, Prosvirova, V G, Motin, S K, Karsanova, N A, Chel'naia, V V, Iasnetsov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 76(4)
It was established that mexidol (100 mg/kg, i.v.) in contrast to cytoflavin (1 ml/kg, i.v.) and reamberin (100 mg/kg, i.v.) produced analgesic effect in rabbits by raising pain threshold under electric stimulation of dental pulp. Mexidol (200 mg/kg,
Publikováno v:
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 46(6)
Experiments with mice showed that, unlike reamberin (100 mg/kg), mexidol (100 mg/kg) and cytoflavin (1 ml/kg) act as antihypoxants in pressure and hermetic chambers but not in case of acute hemic and histotoxic hypoxia. Amtisol succinate (100 mg/kg),