Zobrazeno 1 - 10
of 156
pro vyhledávání: '"S Jill James"'
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 3, p e1005385 (2017)
The number of diagnosed cases of Autism Spectrum Disorders (ASD) has increased dramatically over the last four decades; however, there is still considerable debate regarding the underlying pathophysiology of ASD. This lack of biological knowledge res
Externí odkaz:
https://doaj.org/article/9590a7632ce841b78b0b8e2052249df2
Autor:
Svitlana Shpyleva, Samuil Ivanovsky, Aline de Conti, Stepan Melnyk, Volodymyr Tryndyak, Frederick A Beland, S Jill James, Igor P Pogribny
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113712 (2014)
The molecular pathogenesis of autism is complex and involves numerous genomic, epigenomic, proteomic, metabolic, and physiological alterations. Elucidating and understanding the molecular processes underlying the pathogenesis of autism is critical fo
Externí odkaz:
https://doaj.org/article/116c99930f954bb0a757f79588f11f4e
Autor:
Shannon Rose, Richard E Frye, John Slattery, Rebecca Wynne, Marie Tippett, Oleksandra Pavliv, Stepan Melnyk, S Jill James
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85436 (2014)
There is increasing recognition that mitochondrial dysfunction is associated with the autism spectrum disorders. However, little attention has been given to the etiology of mitochondrial dysfunction or how mitochondrial abnormalities might interact w
Externí odkaz:
https://doaj.org/article/265b65bc38d140dfbced1f60cdeaf3c3
Autor:
Meghan E. Carey, Apollo Kivumbi, Juliette Rando, A. Clementina Mesaros, Stepan Melnyk, S. Jill James, Lisa A. Croen, Heather Volk, Kristen Lyall
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 38, Iss , Pp 100775- (2024)
Oxidative stress during pregnancy has been a mechanistic pathway implicated in autism development, yet few studies have examined this association directly. Here, we examined the association of prenatal levels of 8-iso-PGF2α, a widely used measure of
Externí odkaz:
https://doaj.org/article/c3157fa1ffc14a089bed014ab6fc5183
Autor:
Andrew W. Zimmerman, Kanwaljit Singh, Susan L. Connors, Hua Liu, Anita A. Panjwani, Li-Ching Lee, Eileen Diggins, Ann Foley, Stepan Melnyk, Indrapal N. Singh, S. Jill James, Richard E. Frye, Jed W. Fahey
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-22 (2021)
Abstract Background Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder (ASD) through its effects on several metabolic and immunologic pathways. Previous clinical trials of oral SF demonstrate
Externí odkaz:
https://doaj.org/article/cfdd1aa8a2284064ac4e1899d7e775ee
Autor:
Kathryn Hollowood-Jones, James B. Adams, Devon M. Coleman, Sivapriya Ramamoorthy, Stepan Melnyk, S. Jill James, Bryan K. Woodruff, Elena L. Pollard, Christine L. Snozek, Uwe Kruger, Joshua Chuah, Juergen Hahn
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-19 (2020)
Abstract Background Previous research studies have demonstrated abnormalities in the metabolism of mothers of young children with autism. Methods Metabolic analysis was performed on blood samples from 30 mothers of young children with Autism Spectrum
Externí odkaz:
https://doaj.org/article/b309cd990d8d4a15868b467d49e745fc
Autor:
Andrew W. Zimmerman, Kanwaljit Singh, Susan L. Connors, Hua Liu, Anita A. Panjwani, Li‑Ching Lee, Eileen Diggins, Ann Foley, Stepan Melnyk, Indrapal N. Singh, S. Jill James, Richard E. Frye, Jed W. Fahey
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/4a6d45ef886a477085c6bce5bff063f9
Autor:
Meghan E. Carey, Juliette Rando, Stepan Melnyk, S Jill James, Nathaniel Snyder, Carolyn Salafia, Lisa A. Croen, M Daniele Fallin, Irva Hertz-Picciotto, Heather Volk, Craig Newschaffer, Kristen Lyall
Publikováno v:
Journal of Autism and Developmental Disorders.
We examined associations between prenatal oxidative stress (OS) and child autism-related outcomes. Women with an autistic child were followed through a subsequent pregnancy and that younger sibling's childhood. Associations between glutathione (GSH),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a406418243da8068fe9ded2f969fb6
https://doi.org/10.1007/s10803-022-05625-9
https://doi.org/10.1007/s10803-022-05625-9
Autor:
Marie A. Caudill, S. Jill James, Charles E. Mordaunt, Ralph Green, Olga V. Malysheva, Janine M. LaSalle, Blythe Durbin-Johnson, Yihui Zhu, Rebecca J. Schmidt, M. Daniele Fallin, Stepan Melnyk, Irva Hertz-Picciotto, Joshua W. Miller
Publikováno v:
Autism Research
The prenatal period is a critical window for the development of autism spectrum disorder (ASD). The relationship between prenatal nutrients and gestational gene expression in mothers of children later diagnosed with ASD or non-typical development (No
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68bb50d37a6e2aa77e62e5fb920d6bc6
https://doi.org/10.1002/aur.2428
https://doi.org/10.1002/aur.2428
Autor:
Manish Arora, Janet Cakir, Marie Tippett, Sirish C. Bennuri, Raymond F. Palmer, Christine Austin, Stepan Melnyk, Paul Curtin, Shannon Rose, Leanna Delhey, S. Jill James, Richard E. Frye
Publikováno v:
Molecular Psychiatry
We investigate the role of the mitochondrion, an organelle highly sensitive to environmental agents, in the influence of prenatal air pollution exposure on neurodevelopment and behavior in 96 children with autism spectrum disorder (ASD) [45 with neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2616bd09bc18c69b9d422f371990692e
http://europepmc.org/articles/PMC8159748
http://europepmc.org/articles/PMC8159748