Zobrazeno 1 - 10
of 12
pro vyhledávání: '"S Javad, Rasouli"'
Autor:
Deepika Dogra, Suchit Ahuja, Hyun-Taek Kim, S. Javad Rasouli, Didier Y. R. Stainier, Sven Reischauer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Zebrafish can regenerate damaged myocardial tissue but it is unclear how this is regulated. Here, the authors show that two TGF-β family members, Mstnb and Inhbaa, have opposite effects in regeneration, with mstnb overexpression or inhbaa loss-of-fu
Externí odkaz:
https://doaj.org/article/fc12044a70574a67a382a1e8e1be1850
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Cardiac trabeculae (which are sponge-like muscular structures) form mostly as a result of cardiomyocyte (CM) delamination in zebrafish. Here, the authors identify Nrg2a in zebrafish as a key regulator of trabeculation, and atrial and non-contractile
Externí odkaz:
https://doaj.org/article/311ce37c5db44cac88ab4718b4dabeb3
Autor:
Hyouk-Bum Kwon, Shengpeng Wang, Christian S. M. Helker, S. Javad Rasouli, Hans-Martin Maischein, Stefan Offermanns, Wiebke Herzog, Didier Y. R. Stainier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Endothelial cells align in the direction of flow in response to shear stress. Here the authors describe a zebrafish model for visualization of endothelial polarization and demonstrate that endothelial cell alignment depends on blood flow and Apelin s
Externí odkaz:
https://doaj.org/article/eac965749fac40fca0169a882620ff6c
Autor:
Pourya Sarvari, Srinivas Allanki, Oliver A. Stone, Johannes Graumann, Didier Y.R. Stainier, S. Javad Rasouli, Anna M. Sokol
Publikováno v:
Developmental biology. 480
Cardiac trabeculae are muscular ridge-like structures within the ventricular wall that are crucial for cardiac function. In zebrafish, these structures first form primarily through the delamination of compact wall cardiomyocytes (CMs). Although defec
Autor:
Hiroyuki Nakajima, Naoki Mochizuki, Vanesa Jiménez-Amilburu, David W. Staudt, S. Javad Rasouli, Ayano Chiba, Didier Y.R. Stainier
Publikováno v:
Cell Reports. 17:2687-2699
Despite great strides in understanding cardiac trabeculation, many mechanistic aspects remain unclear. To elucidate how cardiomyocyte shape changes are regulated during this process, we engineered transgenes to label their apical and basolateral memb
Autor:
Wiebke Herzog, Didier Y.R. Stainier, Hans-Martin Maischein, Stefan Offermanns, S. Javad Rasouli, Shengpeng Wang, Christian S. M. Helker, Hyouk-Bum Kwon
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications
Nature Communications
Endothelial cells (ECs) respond to shear stress by aligning in the direction of flow. However, how ECs respond to flow in complex in vivo environments is less clear. Here we describe an endothelial-specific transgenic zebrafish line, whereby the Golg
Autor:
Naoki Mochizuki, Radhan Ramadass, Hiroyuki Nakajima, Ayano Chiba, Sven Reischauer, S. Javad Rasouli, Deepika Dogra, Didier Y.R. Stainier, Felix Gunawan, Veronica Uribe
Cardiomyocyte proliferation is crucial for cardiac growth, patterning and regeneration; however, few studies have investigated the behavior of dividing cardiomyocytes in vivo. Here, we use time-lapse imaging of beating hearts in combination with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e68ce9cccb2da6d9e4dfbf984499986
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/52458
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/52458
Autor:
Didier Y.R. Stainier, Sven Reischauer, Deepika Dogra, Hyun-Taek Kim, S. Javad Rasouli, Suchit Ahuja
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Zebrafish regenerate damaged myocardial tissue very effectively. Hence, insights into the molecular networks underlying zebrafish heart regeneration might help develop alternative strategies to restore human cardiac performance. While TGF-β signalin
Autor:
Maryam Rafipour, Marie Saghaeian Jazi, Tayebeh Minaei, S. Mahmoud A. Najafi, Sara Ansari, Sara Salmanian, Maryam Rezaei Arjomand, Leily Kashkooli, S. Javad Rasouli, Hamideh Shahheydari
Publikováno v:
Biochemical and Biophysical Research Communications. 395:577-582
Recent studies have shown that heterotrimeric G proteins are involved in the regulation of the canonical Wnt/beta-Catenin pathway. However, the mechanism(s) behind this involvement is (are) poorly understood. Our previous results have shown that acti
Autor:
S. Javad Rasouli, Didier Y.R. Stainier
Publikováno v:
Mechanisms of Development. 145:S6