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The local lymph node assay: Results of a final inter-laboratory validation under field conditions

Autor: M. C. Robbins, C. D. Evans, A. E. Sarll, S. J. Waite, K. Miller, Ian Kimber, E.W. Scholes, P. T. C. Harrison, D. A. Basketter

Publikováno v: Journal of Applied Toxicology. 12:217-222

The local lymph node assay (LLNA) assesses the sensitizing activity of chemicals by measurement of primary lymphocyte proliferation in lymph nodes draining the site of application. In this final inter-laboratory study the consistency of LLNA results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f84371f24bc11241cd641a07f399089
https://doi.org/10.1002/jat.2550120312

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Interlaboratory Evaluation of the Local Lymph Node Assay with 25 Chemicals and Comparison with Guinea Pig Test Data

Autor: Ian Kimber, P. T. C. Harrison, M. C. Robbins, K. Miller, P.A. Botham, J. Hilton, S. J. Waite, David A. Basketter, E.W. Scholes

Publikováno v: Toxicology Methods. 1:30-43

Summary: The murine local lymph node assay (LLNA) has been developed as an alternative method for the identification of skin sensitizing chemicals. Measurement is made of the proliferation of lymphocytes within lymph nodes draining the site of exposu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3547445b0625e9441820ac637863e04f
https://doi.org/10.3109/15376519109036523

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Absence of 22q11 deletions in 211 patients with developmental delay analysed using PCR

Autor: J C K Barber, S J Waite, N S Thomas

The 22q11 deletion syndrome has been described by the acronym “CATCH 22” (Cardiac defects, Abnormal facies, Thymic hypoplasia, Cleft palate, and Hypocalcaemia resulting from 22q11 deletions).1 Previous studies have indicated that other features s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7639b0120d3cb46f240a88ab3d0c042
https://europepmc.org/articles/PMC1735094/

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Akademický článek

The local lymph node assay: results of a final inter-laboratory validation under field conditions

Autor: Evans, C. D., Harrison, P. T. C., Robbins, M. C., Sarll, A. E., Scholes, E. W., Waite, S. J. Evans, K. Miller, M. C. Robbins, P. T. C. Harrison, and S. J. Waite, Kimber, I., Miller, K., Basketter, D. A.

Publikováno v: Journal of Applied Toxicology; Jun1992, Vol. 12 Issue 3, p217, 0p

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