Výsledky vyhledávání - "S J Silverman"

Nikkomycin Z is a specific inhibitor of Saccharomyces cerevisiae chitin synthase isozyme Chs3 in vitro and in vivo

Autor: Donald R. Kirsch, Joann P. Gaughran, Margaret H. Lai, S. J. Silverman

Publikováno v: Journal of Bacteriology. 176:5857-5860

Nikkomycin Z inhibits chitin synthase in vitro but does not exhibit antifungal activity against many pathogens. Assays of chitin synthase isozymes and growth assays with isozyme mutants were used to demonstrate that nikkomycin Z is a selective inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d47e85516c6c75ecdcf092852acfb8e
https://doi.org/10.1128/jb.176.18.5857-5860.1994

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ChemInform Abstract: Carbohydrates as Structural Constituents of Yeast Cell Wall and Septum

Autor: Enrico Cabib, Blair Bowers, J. A. Shaw, Hee-Myung Park, S. Das Gupta, P. C. Mol, J. T. Mullins, S. J. Silverman

Publikováno v: ChemInform. 22

The cell walls and septa of fungi a re useful models for morphogenesis and potential targets for anti fungal agents. In the yeast, Saccharomvces cerevisiae, the main structural components of the primary septum and of the cell wall are chitin and ,¶(

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb76ca44c92182114bea7499b8d4b0f5
https://doi.org/10.1002/chin.199139327

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The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle

Autor: A Durán, Enrico Cabib, María Henar Valdivieso, Blair Bowers, J. A. Shaw, S J Silverman, P. C. Mol

Publikováno v: Scopus-Elsevier
The Journal of Cell Biology

The morphology of three Saccharomyces cerevisiae strains, all lacking chitin synthase 1 (Chs1) and two of them deficient in either Chs3 (calR1 mutation) or Chs2 was observed by light and electron microscopy. Cells deficient in Chs2 showed clumpy grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fce45cda2055cc483fe52b5da10249
https://doi.org/10.1083/jcb.114.1.111

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Carbohydrates as structural constituents of yeast cell wall and septum

Autor: Hee-Myung Park, J. A. Shaw, Blair Bowers, P. C. Mol, S. J. Silverman, S. Das Gupta, Enrico Cabib, J. T. Mullins

Publikováno v: Pure and Applied Chemistry. 63:483-489

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32f77f0fa48032b0f0ac1c780acd8100
https://doi.org/10.1351/pac199163040483

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Cell wall active antifungal compounds produced by the marine fungus Hypoxylon oceanicum LL-15G256. III. Biological properties of 15G256 gamma

Autor: Guido Albert, Margaret H. Lai, Patricia A. Bradford, Annerose Rehnig, Van Cotter, Ewald Sieverding, Albaugh David A, James Donald Froyd, S. J. Silverman, Joann P. Gaughran, Donald R. Kirsch

Publikováno v: The Journal of antibiotics. 51(3)

15G256 gamma is a cyclic lipopeptide antifungal agent discovered in a mechanism of action screen for cell wall acting antifungal agents. The compound shows moderate activity in both greenhouse tests against plant disease caused by pathogenic fungi an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c9ad127b2e7570daba3bba33462fa9
https://pubmed.ncbi.nlm.nih.gov/9589067

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Multiple copies of PBS2, MHP1 or LRE1 produce glucanase resistance and other cell wall effects in Saccharomyces cerevisiae

Autor: M H, Lai, S J, Silverman, J P, Gaughran, D R, Kirsch

Publikováno v: Yeast (Chichester, England). 13(3)

Five sequences were isolated by selection for multiple copy plasmids that conferred resistance to laminarinase, an enzyme that specifically degrades cell wall beta(1-3) glucan linkages. Strains carrying three of these plasmids showed alterations in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2428ce76f9a485a06aada7a77e7b337
https://pubmed.ncbi.nlm.nih.gov/9090049

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Chitin Synthetases 1 and 2 from Yeast, Two Isoenzymes with Different Functions

Autor: E. Cabib, S. J. Silverman, J. A. Shaw

Publikováno v: Fungal Cell Wall and Immune Response ISBN: 9783642760761

Chitin, a linear polymer of β(1–4)-linked N-acetylglucosamine, is a major structural component of the cell wall and septum in many fungi. In Saccharomyces cerevisiae, its localization is restricted to a specific area, a circumstance that facilitat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9bd38db752598494101b1ea879bf4e9
https://doi.org/10.1007/978-3-642-76074-7_4

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Regulation of HIS4-lacZ fusions in Saccharomyces cerevisiae

Autor: David Botstein, S J Silverman, Mark D. Rose, Gerald R. Fink

Publikováno v: Scopus-Elsevier

The beginning of the Saccharomyces cerevisiae HIS4 gene has been fused to the structural gene for Escherichia coli beta-galactosidase. This construction, which contains HIS4 DNA from -732 to +30 relative to the translation initiation codon, has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de127a2192dbe3cc42d0b2c9bf159bb
https://doi.org/10.1128/mcb.2.10.1212

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