Zobrazeno 1 - 4
of 4
pro vyhledávání: '"S J Mihalik"'
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 11, Pp 2288-2295 (1996)
In Refsum disease, disorders of peroxisome biogenesis, and rhizomelic chondrodysplasia punctata, pathological accumulation of phytanic acid results from impaired alpha-oxidation of this branched-chain fatty acid. Previous studies from this laboratory
Externí odkaz:
https://doaj.org/article/d15cdb6523e54719b732992f2e945aec
Publikováno v:
The Biochemical journal.
L-Pipecolic acid oxidase activity is deficient in patients with peroxisome biogenesis disorders (PBDs). Because its role, if any, in these disorders is unknown, we cloned the associated human gene and expressed its protein product. The cDNA was clone
Publikováno v:
The EMBO journal. 15(13)
Fluorescent peroxisomal probes were developed by fusing green fluorescent protein (GFP) to the matrix peroxisomal targeting signals PTS1 and PTS2, as well as to an integral peroxisomal membrane protein (IPMP). These proteins were used to identify and
Autor:
S J, Mihalik, W J, Rhead
Publikováno v:
The Journal of biological chemistry. 264(5)
L-Pipecolic acid oxidation was studied in the rabbit and cynomolgus monkey. Tissue homogenates from both species incubated with L-[2,3,4,5,6-3H]pipecolic acid produced a single radioactive product identified as alpha-aminoadipic acid. In the rabbit,