Výsledky vyhledávání

Prognostic Factors in Children With Extragonadal Malignant Germ Cell Tumors: A Pediatric Intergroup Study

Autor: Wendy B. London, Fred Rescorla, Richard B. Womer, Marcio H. Malogolowkin, A. Lindsay Frazier, Neyssa Marina, Thomas A. Olson, B. Cushing, Robert P. Castleberry, S J Lauer

Publikováno v: Journal of Clinical Oncology. 24:2544-2548

Purpose To investigate prognostic factors for pediatric extragonadal malignant germ cell tumors (PEMGCT). Materials and Methods Between 1990 and 1996, patients with stage I through IV PEMGCT were eligible for a trial of cisplatin dose intensity. We r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651a3b817cdcc7650027288c81d742d8
https://doi.org/10.1200/jco.2005.04.1251

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Treatment of Children and Adolescents With Stage II Testicular and Stages I and II Ovarian Malignant Germ Cell Tumors: A Pediatric Intergroup Study—Pediatric Oncology Group 9048 and Children's Cancer Group 8891

Autor: Mary M. Davis, Roger Giller, B. Cushing, John W. Cullen, Neyssa Marina, Thomas A. Olson, Deborah F. Billmire, Paul Rogers, Wendy B. London, Frederick J. Rescorla, S J Lauer

Publikováno v: Journal of Clinical Oncology. 22:3563-3569

Purpose To determine whether children with localized gonadal malignant germ cell tumors (MGCT) stage II testicular and stages I and II ovarian treated with four cycles of standard-dose cisplatin combined with etoposide and low-dose bleomycin (PEB) ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2850c85ba7a528ca6ffde0bd47f5ad80
https://doi.org/10.1200/jco.2004.01.006

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Genetic Analysis of Childhood Endodermal Sinus Tumors by Comparative Genomic Hybridization

Autor: Jie Hu, Robert P. Castleberry, Elizabeth J. Perlman, S J Lauer, Deborah Ho, Barbara Cushing

Publikováno v: Journal of Pediatric Hematology/Oncology. 22:100-105

Childhood endodermal sinus tumors (CEST) are a distinct category of germ cell tumors that involve the testis and extragonadal sites of young children. Recurrent deletions of 1p and 6q have been reported by classic cytogenetic analysis of a small numb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b3523da3d001a1c9c8815b6123db8b
https://doi.org/10.1097/00043426-200003000-00003

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Improved Survival of Children With Isolated CNS Relapse of Acute Lymphoblastic Leukemia: A Pediatric Oncology Group Study

Autor: A K, Ritchey, B H, Pollock, S J, Lauer, Y, Andejeski, J, Barredo, G R, Buchanan

Publikováno v: Journal of Clinical Oncology. 17:3745-3752

PURPOSE: Isolated meningeal relapse in children with acute lymphoblastic leukemia (ALL) usually has been followed by bone marrow relapse and limited survival. The purpose of this study was to prevent marrow relapse by administering intensive therapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9e243fe026eb5750c6599aaee06857
https://doi.org/10.1200/jco.1999.17.12.3745

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Intermediate-dose intravenous methotrexate with intravenous mercaptopurine is superior to repetitive low-dose oral methotrexate with intravenous mercaptopurine for children with lower-risk B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group phase III trial

Autor: Naomi J. Winick, Donald H. Mahoney, Bruce M. Camitta, J J Shuster, R Nitschke, S J Lauer, C P Steuber

Publikováno v: Journal of Clinical Oncology. 16:246-254

PURPOSE To determine whether early intensification with 12 courses of intravenous methotrexate and intravenous mercaptopurine (IVMTX/IVMP) is superior to 12 courses of repetitive, low-dose oral MTX with I.V. MP (LDMTX/IVMP) for prevention of relapse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1000d39290c026a00f42c77d82301ece
https://doi.org/10.1200/jco.1998.16.1.246

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Prognostic Significance of Fluorescence Intensity of Surface Marker Expression in Childhood B-Precursor Acute Lymphoblastic Leukemia. A Pediatric Oncology Group Study

Autor: Donald H. Mahoney, D. Jeanette Pullen, Bruce M. Camitta, S J Lauer, Jonathan J. Shuster, Michael J. Nash, Michael J. Borowitz, A. Thomas Look, Andrew J. Carroll

Publikováno v: Blood. 89:3960-3966

This report describes the prognostic significance of the intensity of surface membrane antigen expression in a series of 1,231 children older than 1 year with newly diagnosed B-precursor acute lymphoblastic leukemia (ALL) treated on Pediatric Oncolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9d9b8e38b9a6421e5860fbd4e38a8ab
https://doi.org/10.1182/blood.v89.11.3960

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Repetitive low dose oral methotrexate and intravenous mercaptopurine treatment for patients with lower risk B—lineage acute lymphoblastic leukemia. A pediatric oncology group pilot study

Autor: C. P. Steuber, Donald H. Mahoney, Jonathan J. Shuster, D. J. Ganick, C. J. Civin, S J Lauer, Bruce M. Camitta, B. G. Leventhal, B. A. Kamen

Publikováno v: Cancer. 75:2623-2631

Background. This trial evaluated the toxicity and preliminary efficacy of a repeated oral low dose (LD) methotrexate schedule with intravenous mercaptopurine infusions as intensification therapy for children with lower risk B-lineage acute lymphoblas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ec8a587c77a2ecd81d3eae7678443f4
https://doi.org/10.1002/1097-0142(19950515)75:10<2623::aid-cncr2820751033>3.0.co

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Intensive intravenous methotrexate and mercaptopurine treatment of higher-risk non-T, non-B acute lymphocytic leukemia: A Pediatric Oncology Group study

Autor: L Munoz, Curt I. Civin, Stuart E. Adair, Bennett L. Leventhal, Douglas Strother, Bruce M. Camitta, Jonathan J. Shuster, P Steuber, S J Lauer, Donald H. Mahoney

Publikováno v: Journal of Clinical Oncology. 12:1383-1389

PURPOSE To determine the potential efficacy and toxicity of intravenous (i.v.) methotrexate (MTX) and mercaptopurine (MP) as postremission intensification treatment for children with B-lineage acute lymphoblastic leukemia (ALL) at higher risk to rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03839133c0b4fca5289b8c9789d8ae1d
https://doi.org/10.1200/jco.1994.12.7.1383

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Enhanced binding and uptake of remnant lipoproteins by hepatic lipase-secreting hepatoma cells in culture

Autor: Zhong-Sheng Ji, John M. Taylor, Robert W. Mahley, André Bensadoun, S J Lauer, Sergio Fazio

Publikováno v: Journal of Biological Chemistry. 269:13429-13436

Rat hepatoma McA-RH7777 cells transfected with a human hepatic lipase (HL) cDNA synthesized and secreted 50-80 ng of human HL/mg of cell protein at 4 h, approximately 50% of which was bound to cell-surface heparan sulfate proteoglycans (HSPG). The ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1fbce20e174b874fa9867042f9a0362
https://doi.org/10.1016/s0021-9258(17)36850-3

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Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E

Autor: Jaijing Wang, S J Lauer, Karl H. Weisgraber, H. V. De Silva, W S Simonet, Robert W. Mahley, J M Taylor

Publikováno v: Journal of Biological Chemistry. 269:2324-2335

Overexpression of human apolipoprotein (apo) C-III in the plasma of transgenic mice results in hypertriglyceridemia, with up to a 20-fold elevation in plasma triglyceride. Nearly all of the triglyceride accumulates in the d < 1.006 g/ml lipoprotein f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17c286e0d843630ce72dcc8c76c4e710
https://doi.org/10.1016/s0021-9258(17)42171-5

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