Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S J Krinzman"'
Autor:
James A. Listman, George T. De Sanctis, Manuela Cernadas, Lester Kobzik, David L. Perkins, David C. Christiani, Hitoshi Kikutani, Patricia W. Finn, Carolyn E. Donovan, S J Krinzman, David A. Mark
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 20:1-8
CD23, a receptor for immunoglobulin E, is expressed at increased levels in asthmatic and atopic individuals and has been associated with disorders characterized by chronic inflammation. Using an established murine model, we employed several complemen
Autor:
G. T. De Sanctis, Lester Kobzik, S J Krinzman, Mohamed H. Sayegh, Carolyn E. Donovan, David L. Perkins, D A Mark, Peter S. Linsley, James A. Lederer, Patricia W. Finn
Publikováno v:
International Immunology. 10:1647-1655
We examined the roles of CD80 (B7-1) and CD86 (B7-2) in a model of allergic pulmonary inflammation and airway hyper-responsiveness (AHR) by selectively inhibiting either CD80 or CD86. Inhibition of co-stimulation by either CD80 or CD86 affected multi
Autor:
David L. Perkins, Maria Luz Lara-Marquez, David C. Christiani, Elliot Israel, James A. Listman, Hongzhen He, S J Krinzman, Aaron Deykin, Patricia W. Finn
Publikováno v:
Journal of Allergy and Clinical Immunology. 101:699-708
T helper cells are a heterogeneous group of cells that have phenotypic and functional differences. Activated T helper cells have been found in peripheral blood after allergen challenge of subjects with atopic asthma, but the phenotypes of specific T
Autor:
Yi Wang, David A. Mark, James A. Listman, David C. Christiani, David L. Perkins, Patricia W. Finn, Carolyn E. Donovan, Manuela Cernadas, S J Krinzman, I Katona, K Nassr, Lester Kobzik, G. T. De Sanctis
Publikováno v:
Journal of Clinical Investigation. 98:2693-2699
Activation of naive T cells requires at least two signals. In addition to the well characterized interaction of the T cell antigen receptor with the antigen/MHC expressed on an antigen-presenting cell, T cell activation also requires costimulation by
Autor:
David L. Perkins, S J Krinzman, David C. Christiani, Patricia W. Finn, G. T. De Sanctis, Lester Kobzik, Manuela Cernadas, James A. Listman
Publikováno v:
The American journal of physiology. 271(3 Pt 1)
To determine the mechanisms by which inhaled antigens produce pulmonary inflammation and bronchial hyperreactivity, we have developed a murine model of asthma. BALB/c mice are sensitized and challenged with ovalbumin (OVA). Compared with mice treated