Zobrazeno 1 - 10
of 101
pro vyhledávání: '"S J Klebanoff"'
Publikováno v:
Journal of Lipid Research, Vol 29, Iss 10, Pp 1379-1385 (1988)
Human monocyte-derived macrophages secrete lipoprotein lipase (LPL) in culture. The regulation of human macrophage LPL production is poorly understood. Since bacterial lipopolysaccharide (LPS) alters production of several macrophage secretory product
Externí odkaz:
https://doaj.org/article/85b0db4c7e92478094873097a11a2e7a
Publikováno v:
The Journal of Immunology. 155:2175-2184
The phosphotyrosine phosphatase CD45 is expressed on the surface of all leukocytes and is known to play a critical role in the regulation of both T and B cell function. In contrast, relatively little information exists regarding the role of CD45 in t
Autor:
F Kazazi, S J Klebanoff
Publikováno v:
Journal of Clinical Microbiology. 33:2054-2057
Human immunodeficiency virus type 1 (HIV-1) is rapidly inactivated by exposure to a naturally occurring antimicrobial system consisting of peroxidase, H2O2, and a halide. Among the potential sources of H2O2 is the amine oxidase system in which mono-,
Autor:
S J, Klebanoff, S, Olszowski, W C, Van Voorhis, J A, Ledbetter, A M, Waltersdorph, K G, Schlechte
Publikováno v:
Blood. 80:225-234
Human polymorphonuclear leukocytes (PMN) preincubated overnight with 100 U/mL gamma-interferon (IFN-gamma) had an increased metabolic response, as measured by iodination and/or superoxide production, to stimulation by tumor necrosis factor (TNF), gra
Autor:
H Rosen, S J Klebanoff
Publikováno v:
Novartis Foundation Symposia ISBN: 9780470715413
Ciba Foundation Symposium 65-Oxygen Free Radicals and Tissue Damage
Ciba Foundation Symposium 65-Oxygen Free Radicals and Tissue Damage
Myeloperoxidase (MPO), H2O2 and a halide form a powerful antimicrobial system effective against bacteria, fungi, viruses and mammalian cells. After phagocytosis, MPO is released into the phagosome from adjacent granules where it interacts with H2O2 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a2fc9b454233dc1508861caadf4dc17
https://doi.org/10.1002/9780470715413.ch15
https://doi.org/10.1002/9780470715413.ch15
Publikováno v:
Biochemical Journal. 272:51-57
The susceptibility of rat mast-cell heparin to oxidative degradation was examined. Heparin as a component of intact mast-cell granules (MCG) was degraded following ingestion by normal human neutrophils. In contrast, neutrophils from patients with chr
Autor:
W C Liles, S J Klebanoff
Publikováno v:
The Journal of Immunology. 155:3289-3291
Publikováno v:
Journal of leukocyte biology. 70(1)
Modulins represent microbial products that stimulate cytokine production in host cells. The modulins responsible for gram-positive sepsis remain poorly understood. Staphylococci release a factor (or factors) that activates nuclear factor-kappa B and
Publikováno v:
Journal of medical primatology. 29(1)
Myeloperoxidase (MPO) is an enzyme in neutrophils and monocytes which reacts with H2O2 and chloride to kill microbes after phagocytosis. Instillation of MPO into the vagina may augment vaginal defenses against sexually transmitted diseases, since the