Zobrazeno 1 - 10
of 15
pro vyhledávání: '"S J Hedley"'
Autor:
Martin Heaton, David J. Gawkrodger, C Layton, S J Hedley, Sheila Mac Neil, R. A. Dawson, Kaushik H. Chakrabarty
Publikováno v:
Pigment Cell Research. 15:49-56
Human melanocytes in monolayer culture are extremely dependent on a wide range of soluble signals for their proliferation and melanogenesis. The advent of three-dimensional models of reconstructed skin allows one to ask questions of how these cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424dc702eb1c6fb3fba5a6fc9fa28fd8
https://doi.org/10.1034/j.1600-0749.2002.00067.x
https://doi.org/10.1034/j.1600-0749.2002.00067.x
Autor:
E. Freedlander, L. Smith-Thomas, S J Hedley, J. Phillips, R. A. Dawson, C.M. Caddy, David J. Gawkrodger, S. Mac Neil
Publikováno v:
Pigment Cell Research. 14:116-125
A pilot study for grafting of patients with vitiligo using cultured epithelial autografts containing melanocytes gave disappointing clinical results, with pigmentation achieved in only one out of five patients. Irrespective of the fate of melanocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10755a1fb6a043bcfd4e969f47929448
https://doi.org/10.1034/j.1600-0749.2001.140207.x
https://doi.org/10.1034/j.1600-0749.2001.140207.x
Autor:
Ghanem Elias Ghanem, R Morandini, David J. Gawkrodger, S J Hedley, AK Murray, Karen Sisley, S. Mac Neil
Publikováno v:
Melanoma Research. 10:323-330
This study was undertaken to investigate whether alpha-melanocyte stimulating hormone (alphaMSH) influences the interaction of melanoma cells with T-lymphocytes in the light of previous work from our laboratories showing that alphaMSH can reduce tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0341eb3dd7fb81b03cad0aaeb2cdab
https://doi.org/10.1097/00008390-200008000-00003
https://doi.org/10.1097/00008390-200008000-00003
Autor:
P Eves, Ghanem Elias Ghanem, R. A. Dawson, S. Mac Neil, C Layton, S J Hedley, Martin Wagner, R Morandini
Publikováno v:
British Journal of Dermatology. 142:210-222
The purpose of this study was to compare the invasive properties of normal human cutaneous melanocytes and of a cutaneous melanoma cell line (HBL) in a three-dimensional model of reconstructed human skin. Specifically, we asked to what extent the pig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1237e2dbc55cdbef950337957b8690b
https://doi.org/10.1046/j.1365-2133.2000.03287.x
https://doi.org/10.1046/j.1365-2133.2000.03287.x
Publikováno v:
Scopus-Elsevier
The aim of this study was to investigate whether the presence of pigment affects the sensitivity of pigmented cells of the eye, retinal pigment epithelium (RPE) and choroidal melanocytes (CMs) to the cytotoxic effects of xenobiotic drugs. Two approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9fa14e3f4c7e7e5851a094f25780df
https://doi.org/10.1111/j.1600-0749.1999.tb00504.x
https://doi.org/10.1111/j.1600-0749.1999.tb00504.x
Publikováno v:
Journal of Cellular Physiology. 175:276-282
Alpha-MSH, a proopiomelanocortin (POMC)-derived peptide, is known to be produced in the pituitary, the skin, and melanoma tumors and to possess many biological effects, mainly on melanocyte pigmentation and growth. Moreover, the melanocyte expresses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7635c4889a24762321b8da302fb4ac39
https://doi.org/10.1002/(sici)1097-4652(199806)175:3<276::aid-jcp5>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199806)175:3<276::aid-jcp5>3.0.co
Publikováno v:
Pigment Cell Research. 10:54-59
Cutaneous and ocular melanocytes are routinely cultured in complex mitogen-rich media. The physiological regulation of melanocyte proliferation and differentiation is not yet fully defined and this study summarises several separate lines of evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbb8c770605498fde6d79453b0437fd
https://doi.org/10.1111/j.1600-0749.1997.tb00466.x
https://doi.org/10.1111/j.1600-0749.1997.tb00466.x
Publikováno v:
British Journal of Dermatology. 135:888-897
Several studies have indicated that extracellular matrix (ECM) proteins can influence melanocyte behaviour in vitro. However, the choice of medium is known to have a profound effect on melanocyte behaviour and it is currently difficult to ascribe whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008bb9453e936beeeab7ff4fef267ac9
https://doi.org/10.1046/j.1365-2133.1996.d01-1091.x
https://doi.org/10.1046/j.1365-2133.1996.d01-1091.x
Autor:
Joanne T. Douglas, David T. Curiel, Dominik Escher, Nikolay Korokhov, S Hohn, Joel N. Glasgow, Alcide Barberis, Adrian Auf Der Maur, S J Hedley
Publikováno v:
Gene therapy. 13(1)
Adenovirus (Ad) vectors are of utility for many therapeutic applications. Strategies have been developed to alter adenoviral tropism to achieve a cell-specific gene delivery capacity employing fiber modifications allowing genetic incorporation of tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac8f306477825409b3b27252a35b9c1
https://pubmed.ncbi.nlm.nih.gov/16107860
https://pubmed.ncbi.nlm.nih.gov/16107860
Publikováno v:
The British journal of dermatology. 139(6)
The aetiology of vitiligo remains unclear. An autoimmune involvement has been suggested and, in this study, we examine whether melanocytes cultured from unaffected regions of the skin of vitiligo patients are more susceptible to immune attack by inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df9fed93a05ea024ede615cf80acb339
https://pubmed.ncbi.nlm.nih.gov/9990357
https://pubmed.ncbi.nlm.nih.gov/9990357