Zobrazeno 1 - 10
of 149
pro vyhledávání: '"S J Burakoff"'
Publikováno v:
The Journal of Immunology. 157:110-116
Crk is a Src homology 2 (SH2)/Src homology 3 (SH3)-containing adapter protein that has been implicated in intracellular signaling in fibroblasts and PC12 pheochromocytoma cells. Crk has been shown to bind to a tyrosine-phosphorylated protein of 116 k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e70f74a36581e013b9515ded4566b8b
https://doi.org/10.4049/jimmunol.157.1.110
https://doi.org/10.4049/jimmunol.157.1.110
Publikováno v:
The Journal of Immunology. 156:4535-4538
Thymocytes develop into mature functional T cells in the inductive environment of the thymus where thymocyte-stromal cell interactions and cytokines provide survival and differentiation signals as cues for thymocyte maturation. Disruption of the thym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d090eb530f68b2ed4949708cd5c3484b
https://doi.org/10.4049/jimmunol.156.12.4535
https://doi.org/10.4049/jimmunol.156.12.4535
Publikováno v:
The Journal of Immunology. 154:3213-3221
Thymocytes mature in response to the cues from the thymic micro-environment, which regulate stage-specific gene expression during development. We find that several proteins that bind the kappa B sequence in vitro are constitutively activated in fresh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01922832ec82c1f0128f57023e1c13d9
https://doi.org/10.4049/jimmunol.154.7.3213
https://doi.org/10.4049/jimmunol.154.7.3213
Publikováno v:
The Journal of Immunology. 148:2159-2162
By fluorescence resonance energy transfer, we have previously demonstrated that upon anti-CD3 mAb-mediated activation of a murine T cell hybridoma expressing human CD4, CD4 moves into close association with the TCR/CD3 complex. It was shown that this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2305800786b3c0e6ea8915965bdc4c7
https://doi.org/10.4049/jimmunol.148.7.2159
https://doi.org/10.4049/jimmunol.148.7.2159
Publikováno v:
The Journal of Immunology. 147:428-431
CD4 functions to enhance T cell activation by increasing intercellular adhesion and/or by transduction of an intracellular signal. To study the role of human CD4 in T cell activation we have used a murine T cell hybridoma, By 155.16, which produces I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30c1fcab9c2176a8a90618b479aa41ac
https://doi.org/10.4049/jimmunol.147.2.428
https://doi.org/10.4049/jimmunol.147.2.428
Publikováno v:
The Journal of Immunology. 146:1130-1133
The injection of mature T cells into a tolerant or immunocompromised allogeneic host animal produces a graft versus host response (GVHR) that can result in splenomegaly, immunosuppression and death of the host animal. We demonstrate here that lymphoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53a43696a81f66ce4d4b03e5bd80e94c
https://doi.org/10.4049/jimmunol.146.4.1130
https://doi.org/10.4049/jimmunol.146.4.1130
Publikováno v:
The Journal of Immunology. 144:2925-2930
Expression of CD2 on developing and mature murine B cells was examined by using an antipeptide antiserum (L50). Most Ig-bearing splenic B cells were found to express CD2. Anti-CD5 and anti-B220 mAb divided the peritoneal B cells into two populations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3edd7ea2d429ee710e5c84dea4337b
https://doi.org/10.4049/jimmunol.144.8.2925
https://doi.org/10.4049/jimmunol.144.8.2925
Publikováno v:
The Journal of Immunology. 144:526-531
A possible component of the immune dysfunction associated with infection by HIV is the inhibition of CD4 function resulting from the avid binding of soluble HIV envelope glycoprotein (gp120) to cell surface CD4. We assessed CD4 function by measuring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f81c0a746d01d8f9ea80f58d617a842
https://doi.org/10.4049/jimmunol.144.2.526
https://doi.org/10.4049/jimmunol.144.2.526
Publikováno v:
Transplantation. 70(1)
The Fas/Fas ligand (FasL) pathway plays an important role in a number of apoptotic processes that could be important for the development of graft-versus-host disease (GVHD) after bone marrow transplantation (BMT), such as cytolysis of target cells by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ef265aa916a895496c91c215b4acd70
https://pubmed.ncbi.nlm.nih.gov/10919598
https://pubmed.ncbi.nlm.nih.gov/10919598
Publikováno v:
The Journal of biological chemistry. 275(1)
STAT5, a member of the signal transducers and activators of transcription (STATs), is important in modulating T cell functions through interleukin-2 (IL-2) receptors. Like other STAT proteins, STAT5 undergoes a rapid activation and inactivation cycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3dae851a3ea6a02119ab3c6d247fc2b2
https://pubmed.ncbi.nlm.nih.gov/10617656
https://pubmed.ncbi.nlm.nih.gov/10617656