Zobrazeno 1 - 10
of 17
pro vyhledávání: '"S J, Winder"'
Autor:
G, Mathew, A, Mitchell, J M, Down, L A, Jacobs, F C, Hamdy, C, Eaton, D J, Rosario, S S, Cross, S J, Winder
Publikováno v:
Scientific Reports
Dystroglycan is frequently lost in adenocarcinoma, but the mechanisms and consequences are poorly understood. We report an analysis of β-dystroglycan in prostate cancer in human tissue samples and in LNCaP cells in vitro. There is progressive loss o
Autor:
S. J. Winder
Publikováno v:
Biochemical Society Transactions. 24:497-501
Publikováno v:
The Prostate. 73(4)
Dystroglycan is a ubiquitously expressed cell adhesion molecule frequently found to be altered or reduced in adenocarcinomas, however the mechanisms or consequences of dystroglycan loss have not been studied extensively.We examined the consequence of
Publikováno v:
Journal of Endocrinology. 136:297-304
Sucrose density centrifugation was used to prepare a partially purified membrane fraction from the mammary glands of non-pregnant, pregnant and lactating sheep. The binding of125 I-labelled insulin-like growth factor-I (IGF-I) was dependent on membra
Autor:
S S, Cross, J, Lippitt, A, Mitchell, F, Hollingsbury, S P, Balasubramanian, M W R, Reed, C, Eaton, J W, Catto, F, Hamdy, S J, Winder
Publikováno v:
Histopathology. 53(5)
Dystroglycan is an important structural and signalling protein that is expressed in most human cells. alpha-Dystroglycan has been investigated and found to be reduced in human cancers, but there is only one published study on the expression of beta-d
Autor:
M J F, Broderick, S J, Winder
Publikováno v:
Advances in protein chemistry. 70
Spectrin family proteins represent an important group of actin-bundling and membrane-anchoring proteins found in diverse structures from yeast to man. Arising from a common ancestral alpha-actinin gene through duplications and rearrangements, the fam
Publikováno v:
Journal of biomolecular NMR. 19(2)
Publikováno v:
The Biochemical journal. 337
Monoclonal antibody (mAb) binding sites in the N-terminal actin-binding domain of utrophin have been identified using phage-displayed peptide libraries, and the mAbs have been used to probe functional regions of utrophin involved in actin binding. mA
Autor:
S J, Winder
Publikováno v:
Journal of muscle research and cell motility. 18(6)
Recent studies with transgenic animals have considerably advanced our knowledge of the roles of dystrophin and utrophin in both muscle and non-muscle tissues. Rigorous analyses of the roles of the various mdx mutations in mice, as well as the use of