Zobrazeno 1 - 10
of 20
pro vyhledávání: '"S J, Ullrich"'
Publikováno v:
Journal of Biological Chemistry. 267:23484-23488
Two peptides (PEP1, 26 residues, and PEP2, 22 residues) were synthesized with amino acid sequences identical to two of the long segments of polypeptide chain rich in alanine, proline, and charged amino acids that link the lipoyl domains together in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18a8656dfd944d91059c21dc952bec7
https://doi.org/10.1016/s0021-9258(18)35864-2
https://doi.org/10.1016/s0021-9258(18)35864-2
Publikováno v:
Proceedings of the National Academy of Sciences. 89:9210-9214
Conditional expression of wild-type (wt) p53 protein in a glioblastoma tumor cell line has been shown to be growth inhibitory. We have now more precisely localized the position in the cell cycle where growth arrest occurs. We show that growth arrest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a0fc27c8b95f81ec31826bdce764ad
https://doi.org/10.1073/pnas.89.19.9210
https://doi.org/10.1073/pnas.89.19.9210
Autor:
Heather A. Wakelee, S. J. Ullrich, Anthony W. Tolcher, Monica M. Mita, N. L. Fox, Amita Patnaik, George A. Fisher, R. Miceli, Branimir I. Sikic
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 21(2)
Background: Lexatumumab (HGS-ETR2) is a fully human agonistic mAb to the tumor necrosis factor-related apoptosis-inducing ligand receptor 2 that activates the extrinsic apoptosis pathway and has potent preclinical antitumor activity. Materials and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1479d3b0437f4077bf33bfc6f65b109
https://pubmed.ncbi.nlm.nih.gov/19633048
https://pubmed.ncbi.nlm.nih.gov/19633048
Autor:
Y, Shi, S J, Ullrich, J, Zhang, K, Connolly, K J, Grzegorzewski, M C, Barber, W, Wang, K, Wathen, V, Hodge, C L, Fisher, H, Olsen, S M, Ruben, I, Knyazev, Y H, Cho, V, Kao, K A, Wilkinson, J A, Carrell, R, Ebner
Publikováno v:
The Journal of biological chemistry. 275(25)
As part of a large scale effort to discover novel secreted proteins, a cDNA encoding a novel cytokine was identified. Alignments of the sequence of the new protein, designated IL-17B, suggest it to be a homolog of the recently described T cell-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e326793e59a2cf342b60708de060786
https://pubmed.ncbi.nlm.nih.gov/10749887
https://pubmed.ncbi.nlm.nih.gov/10749887
Publikováno v:
Nature genetics. 9(1)
Structural mutations in the p53 gene are seen in virtually every form of human cancer. To determine whether such mutations are important for initiating tumorigenesis, we have been studying hepatocellular carcinoma, in which most cases are associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0505c493cdb964a1e9ee9c63af72cb
https://pubmed.ncbi.nlm.nih.gov/7704023
https://pubmed.ncbi.nlm.nih.gov/7704023
Publikováno v:
Seminars in cancer biology. 5(1)
The development of human cancer is a complex process which has been difficult to define in vivo. The use of animal models of human cancer may prove useful in elucidating the mechanisms associated with malignant transformation. Transgenic mice with ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8e0a0f0f02508fa05bc484a1de46f90
https://pubmed.ncbi.nlm.nih.gov/8186389
https://pubmed.ncbi.nlm.nih.gov/8186389
Publikováno v:
Oncogene. 8(5)
A method for the isolation of tyrosine kinases substrates was developed. The method takes advantage of immuno-affinity purification of an entire set of proteins phosphorylated by tyrosine kinases, followed by generation of antisera against the purifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88087852558d273206380652444be0ce
https://pubmed.ncbi.nlm.nih.gov/8479753
https://pubmed.ncbi.nlm.nih.gov/8479753
Publikováno v:
Breast cancer research and treatment. 26(1)
To determine, if, as previously observed with rodent uterus, the 90 kilodalton heat shock protein (HSP-90) might be under estrogenic regulation in human mammary tumors, we analyzed its relationship with estrogen and progesterone receptors. A positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db99163c4eb53eebc7fae8ed7479c6d
https://pubmed.ncbi.nlm.nih.gov/8400328
https://pubmed.ncbi.nlm.nih.gov/8400328
Publikováno v:
The Journal of biological chemistry. 267(33)
Two peptides (PEP1, 26 residues, and PEP2, 22 residues) were synthesized with amino acid sequences identical to two of the long segments of polypeptide chain rich in alanine, proline, and charged amino acids that link the lipoyl domains together in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09c4313da482f2f81a8f8340ed35392d
https://pubmed.ncbi.nlm.nih.gov/1429691
https://pubmed.ncbi.nlm.nih.gov/1429691
Publikováno v:
Molecular and cellular biology. 12(11)
Human DNA-PK is a nuclear, serine/threonine protein kinase that, when activated by DNA, phosphorylates several DNA-binding substrates, including the tumor suppressor protein p53. To identify which p53 residues are phosphorylated, we examined DNA-PK's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ac4a90a4fcc91b2c741b12c5bb8a78
https://pubmed.ncbi.nlm.nih.gov/1406679
https://pubmed.ncbi.nlm.nih.gov/1406679