Zobrazeno 1 - 10
of 13
pro vyhledávání: '"S J, Szilvassy"'
Publikováno v:
Proceedings of the National Academy of Sciences. 89:1968-1972
Marrow cells from male mice pretreated with 5-fluorouracil were infected with helper-free neomycin-resistant (neor) recombinant retrovirus and then used to initiate long-term cultures (LTC) on irradiated adherent marrow feeder layers. Four weeks late
Publikováno v:
Proceedings of the National Academy of Sciences. 87:8736-8740
Although hematopoiesis is known to originate in a population of very primitive cells with both lymphopoietic and myelopoietic potential, a procedure for enumerating such cells has to date not been available. We now describe a quantitative assay for l
Publikováno v:
Blood. 76:1071-1076
A large number of biologic, technological, and clinical studies await the development of procedures that will allow totipotent hematopoietic stem cells to be expanded in vitro. Previous work has suggested that hematopoiesis can be reconstituted using
Publikováno v:
Blood. 76:1071-1076
A large number of biologic, technological, and clinical studies await the development of procedures that will allow totipotent hematopoietic stem cells to be expanded in vitro. Previous work has suggested that hematopoiesis can be reconstituted using
Publikováno v:
Blood. 95(9)
Loss of long-term hematopoietic stem cell function in vitro is associated with cell cycle progression. To determine whether cytokine-induced proliferation also limits the rate of short-term engraftment and potential clinical utility of ex vivo expand
Publikováno v:
Blood. 93(5)
Hematopoietic reconstitution of ablated recipients requires that intravenously (IV) transplanted stem and progenitor cells "home" to organs that support their proliferation and differentiation. To examine the possible relationship between homing prop
Publikováno v:
Blood. 88(9)
The ability of an infusion of ex vivo expanded hematopoietic cells to ameliorate cytopenia following transplantation of hematopoietic stem cells (HSCs) is controversial. To address this issue, we measured the recovery of circulating leukocytes, eryth
Autor:
S J, Szilvassy, K P, Weller, W, Lin, A K, Sharma, A S, Ho, A, Tsukamoto, R, Hoffman, K R, Leiby, D P, Gearing
Publikováno v:
Blood. 87(11)
Attempts to maintain or expand primitive hematopoietic stem cells in vitro without the concomitant loss of their differentiative and proliferative potential in vivo have largely been unsuccessful. To investigate this problem, we compared the ability
Autor:
S J, Szilvassy, R, Hoffman
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 1(1)
Autor:
C J, Eaves, H J, Sutherland, C, Udomsakdi, P M, Lansdorp, S J, Szilvassy, C C, Fraser, R K, Humphries, M J, Barnett, G L, Phillips, A C, Eaves
Publikováno v:
Blood cells. 18(2)
A quantitative assay for a primitive human hematopoietic cell has been developed. The cell identified has been assigned the operational designation of long-term culture (LTC)-initiating cell based on its ability when cultured on supportive fibroblast