Zobrazeno 1 - 10
of 30
pro vyhledávání: '"S J, Suchard"'
Publikováno v:
The Journal of Immunology. 159:5568-5575
Although many of the receptors mediating neutrophil (polymorphonuclear leukocyte (PMN)) adhesion to extracellular matrix (ECM) proteins have been identified, the signal transduction pathways leading to cell spreading are not clearly defined. Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::035c42a525dfa3f2242ef0447bca188e
https://doi.org/10.4049/jimmunol.159.11.5568
https://doi.org/10.4049/jimmunol.159.11.5568
Publikováno v:
The Journal of Immunology. 158:4961-4967
In FMLP-activated polymorphonuclear leukocytes (PMNs) challenged with IgG-opsonized erythrocytes (EIgG), the termination of phagocytosis correlates with an accumulation of ceramide, a product of sphingolipid metabolism. Furthermore, the exogenous add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::654f22de3c6450a6d6e98f1db11e1771
https://doi.org/10.4049/jimmunol.158.10.4961
https://doi.org/10.4049/jimmunol.158.10.4961
Publikováno v:
The Journal of Immunology. 152:877-888
Thrombospondin (TSP), a multifunctional homotrimeric glycoprotein of approximately 450,000 M(r), is a component of the extracellular matrix that mediates the adhesive interactions of several different cell types including hematopoietic progenitor cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d058b223b893eb06205bf7b4e1e48b7d
https://doi.org/10.4049/jimmunol.152.2.877
https://doi.org/10.4049/jimmunol.152.2.877
Autor:
P J Mansfield, S J Suchard
Publikováno v:
The Journal of Immunology. 150:1959-1970
Differentiation of the human promyelocytic leukemia cell line HL-60 to polymorphonuclear leukocyte (PMN)-like cells with DMSO provides an important model for studying the acquisition of PMN functional responses that accompany differentiation. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4355732822675304d9620e5f7602165
https://doi.org/10.4049/jimmunol.150.5.1959
https://doi.org/10.4049/jimmunol.150.5.1959
Publikováno v:
The Journal of Immunology. 149:2172-2178
Chemoattractant-induced activation of human polymorphonuclear leukocytes involves receptor coupling to guanine nucleotide binding proteins (G-proteins). Treatment of polymorphonuclear leukocytes with pertussis toxin, which ADP-ribosylates neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f6347f3cfd0a694e7f5a06a62a848aa
https://doi.org/10.4049/jimmunol.149.6.2172
https://doi.org/10.4049/jimmunol.149.6.2172
Publikováno v:
Biochemical Journal. 284:513-520
The extracellular matrix (ECM) protein thrombospondin (TSP) binds specifically to polymorphonuclear leucocyte (PMN) surface receptors and promotes cell adhesion and motility. TSP receptor expression increases 30-fold after activation with the synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6551a65ca12e0c180276776847c89f60
https://doi.org/10.1042/bj2840513
https://doi.org/10.1042/bj2840513
Publikováno v:
The Journal of Immunology. 147:651-659
Thrombospondin (TSP), a 450-kDa extracellular matrix protein secreted by platelets may be instrumental in triggering polymorphonuclear leukocyte (PMN) activation and mediating PMN-endothelial cell interactions. TSP alone had no effect on O-2 generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::449b2b4efd4b41ffe8cb0bea7541701e
https://doi.org/10.4049/jimmunol.147.2.651
https://doi.org/10.4049/jimmunol.147.2.651
Publikováno v:
The Journal of Immunology. 146:3945-3952
Thrombospondin (TSP), a 450-kDa trimeric glycoprotein secreted by platelets and endothelial cells at sites of tissue injury or inflammation, may play an important role in polymorphonuclear leukocyte (PMN) adherence to blood vessel walls before diaped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e69950afc521a3e6540992e13dbea149
https://doi.org/10.4049/jimmunol.146.11.3945
https://doi.org/10.4049/jimmunol.146.11.3945
Publikováno v:
The Journal of Immunology. 144:3936-3945
We have identified two major proteins in human neutrophils that are phosphorylated in vitro by protein kinase C (PKC) as lipocortins III and a fragment of a lipocortin-like 68-kDa protein. In electroporated cells, the 68-kDa protein was phosphorylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd380d135aa1d3ff9dbb9afa9e565b40
https://doi.org/10.4049/jimmunol.144.10.3936
https://doi.org/10.4049/jimmunol.144.10.3936
Publikováno v:
Blood. 91(12)
The sphingomyelin cycle, which plays an important role in regulation of cell growth, differentiation, and apoptosis, involves the formation of ceramide by the action of a membrane-associated, Mg2+-dependent, neutral sphingomyelinase and/or a lysosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a34880508f918b3b407f578e1ba38c8c
https://pubmed.ncbi.nlm.nih.gov/9616175
https://pubmed.ncbi.nlm.nih.gov/9616175